杭海英

1982年四川大學生化專業本科畢業，1986年中科院動物所獲碩士學位，1994年美國科羅拉多州立大學放射衛生系獲博士學位。1994年－1997年在美國哥倫比亞大學放射研究中心做博士后研究。1997年－2004年 在美國哥倫比亞大學放射研究中心從事研究工作，擔任助理教授，主要研究DNA修復、細胞周期調控及與癌發生的關係。研究方向為分子腫瘤學。

2015年

Chen C, Li N, Zhao Y*, Hang H*. Coupling Recombinase-mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells

Li N, An L, Hang H*. Increased Sensitivity of DNA Damage Response-Deficient Cells to Stimulated Microgravity-Induced DNA Lesions

Zhang Z, Cai Z, Li K, Fang Y, An L, Hu Z*, Wang S*, Hang H*. The Effect of lonizing Radiation on mRNA Levels of the DNA Damage Response Genes Rad9, Rad1 and Hus1 in Various Mouse Tissues

2014年

劉春春，趙雲，杭海英. 流式細胞術揭示出枯草芽孢桿菌多態異質性. 生物化學與生物物理進展

Yue H, Zhao Y, Hang H*. Improvement of engineered microbial production of alkanes through a dual-reporter screening system. 生物物理學報

2013年

Yang X, Sun S, Wang HF, Hang H*. Comparison of autotransporter and ice nucleation protein as carrier proteins for antibody display on the cell surface of Escherichia coli

Li T, Wang Z, Zhao Y, He W, An L, Liu S, Liu Y, Wang H, Hang H*. Checkpoint protein Rad9 plays an important role in nucleotide excision repair

2012年

Chen S , Qiu J, Chen C, Liu C, Liu Y, An L, Jia J, Tang J, Wu L, Hang H*. Affinity maturation of anti-TNF-α scFv with somatic hypermutation in non-B cells

Zhao Y, He W, Liu WF, Liu CC, Feng LK, Sun L, Yan YB, Hang HY*. Two distinct states of Escherichia coli cells that overexpress the recombinant heterogeneous β-galactosidase

2011年

Wang Y, An L, Jiang Y, Hang H*. Effects of Simulated Microgravity on Embryonic Stem Cells

Zhang C, Liu Y, Hu Z, An L, He Y, Hang H*. Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses

He W, Ma X, Yang X, Zhao Y, Qiu J, Hang H*. A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage

2010年

An L, Wang Y, Liu Y, Yang X, Liu C, Hu Z, He W, Song W and Hang H*. Rad9 is required for B cell proliferation and immunoglobulin class switch recombination

Qiu J, Jung ST, Georgiou G, Hang HY*. Enrichment of Escherichia coli Spheroplasts Displaying scFv Antibodies specific for antigens expressed on the human cell surface

Cui P, Lin Q, Xin C, Han L, An L, Wang Y, Hu Z, Ding F, Zhang L, Hu S*, Hang H*, Yu J*. Hydroxyurea-induced Global Transcriptional Suppression in Mouse ES Cells

Han L, Hu Z, Liu Y, Wang X, Hopkins KM, Lieberman HB, Hang H*

2009年

Xu M, Bai L, Gong Y, Xie W, Hang H*, Jiang T. Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex

Cui Z, Chen X, Lu B, Park SK, Xu T, Xie Z, Xue P, Hou J, Hang H, Yates JR 3rd, Yang F. Preliminary quantitative profile of differential protein expression between rat L6 myoblasts and myotubes by stable isotope labeling with amino acids in cell culture

2008年

He W, Zhao Y, Zhang C, An L, Hu Z, Liu Y, Han L, Bi L, Xie Z, Xue P, Yang F, Hang H*. Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1

Zhang C, Zhang CX, He Y and Hang H*. Phosphorylation Sites on Tyr28 and the C-terminus of Rad9 are Required for Inhibition of Premature Chromosomal Condensation Across the Entire S Phase

Hu Z, Liu Y, Zhang C, Zhao Y, He W, Han L, Yang L, Hopkins KM, Yang X, Lieberman HB, Hang H*. Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development

Guo Z, Chavez V, Singh P, Finger LD, Hang H, Hegde ML, Shen B. Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways

Wang S, Tang M, Pei B, Xiao X, Wang J, Hang H, Wu L. Cadmium-induced germline apoptosis in Caenorhabditis elegans: the roles of HUS1, p53, and MAPK signaling pathways

Pei B, Wang S, Guo X, Wang J, Yang G, Hang H, Wu L. Arsenite-induced germline apoptosis through a MAPK-dependent, p53-independent pathway in Caenorhabditis elegans

Yuan C, Jiao L, Yang L, Ying W, Hu Z, Liu J, Cui F, Li L, Qian L, Teng Y, Hang H, Qian X, Yang X. The up-regulation of 14-3-3 proteins in Smad4 deficient epidermis and hair follicles at catagen

2007年

Ning Tang, Gangjun Du, Nan Wang, Chunchun Liu, Haiying Hang*, Wei Liang*. Improving Penetration in Tumors with Nano-assemblies of Phospholipids and Doxorubicin

2006年

劉春春 杭海英*. 生物大分子相互作用檢測技術新進展———三色熒光級聯熒光共振能量轉移技術. 生物化學與生物物理進展

蘇華　杭海英*. 生理條件下的S期檢查點. 生物化學與生物物理進展

2004年

Hopkins KM, Auerbach W, Wang XY, Hande MP, Hang H, Wolgemuth DJ, Joyner AL, Lieberman HB. Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality

Hopkins KM, Wang X, Berlin A, Hang H, Thaker HM, Lieberman HB. Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue

Hang H* and Fox MH. Analysis of the mammalian cell cycle by flow cytometry. In Cell Cycl

2002年

Hang H*, Zhang Y, Dunbrack RL, Jr, Wang C, and Lieberman HB. Identification and Characterization of a Paralogue of Human Cell Cycle Checkpoint Gene HUS1

2000年

Komatsu K, Wharton W, Hang H, Wu C, Singh S, Lieberman HB, Pledger WJ, Wang HG. PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition

H. Hang, and H.B. Lieberman. Physical interactions among human checkpoint proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression

Komatsu K, Miyashita T, Hang H, Hopkins KM, Zheng W, Cuddeback S, Yamada M, Lieberman HB, Wang HG. Human homologue of S. pombe rad9 interacts with BCL-2/BCL-x L and promotes apoptosis

H. Hang, Rauth S.J., Hopkins K.M., Lieberman H.B. Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control

1998年

H. Hang, S.J. Rauth, K.M. Hopkins, S.K. Davey. and H.B. Lieberman, Molecular cloning and tissue-specific expression of a murine orthologue of the Schizosaccharomyces pombe rad9 checkpoint control gene

1996年

H. Hang and M.H. Fox. Levels of 70-kDa heat shock protein through the cell cycle in several mammalian cell lines

H. Hang, DN. Hager, L. Goriparthi, KM. Hopkins, H. Shih and HB. Lieberman. Schizosaccharomyces pombe rad23 is allelic with swi10, a mating-type switching/ radioresistance gene that shares sequence homology with human and mouse ERCC1

1995年

H. Hang, L. He and M.H. Fox. Cell cycle variation of hsp70 levels in HeLa cells at 37o C and after a heat shock

H. Hang, L. He and M.H. Fox. Expression of hsp70 induced in CHO cells by 45.0o C hyperthermia is cell cycle associated and DNA synthesis dependent

1994年以前

H. Hang and M.H. Fox. Low pH suppresses synthesis of heat-shock proteins and thermotolerance, Radiation Research

E.D. Wieder, H. Hang and M.H. Fox. The measurement of intracellular pH using flow cytometry with carboxy-SNARF-1

H. Hang, B. Feng, Z. Zhang. Studies on relationship between Na,K-ATPase activity and sperm capacitation in Guinea pig, Science in China (series B)