自磷酸化

自磷酸化

當配體-受體結合時,受體胞外結構域構象變化導致相鄰的單跨膜受體二聚化,以利於受體間的交互磷酸化,即自磷酸化

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含義:
1. it carried phosphate groups attached covalently to one or more of its amino acid side chains
2. it served as a substrate for phosphorylation by a protein kinase
同時可以提供磷酸集團,和作為蛋白質激酶磷酸化的底物