劉曉慶

2003年在山東師範大學化學化工與材料科學學院取得學士學位,2009年初從中國科學院長春應用化學研究所、電分析化學國家重點實驗室獲得博士學位, 獲中科院劉永齡獎學金特別獎。2009至2015年先後在丹麥奧胡斯大學化學系、交叉學科納米中心以及以色列耶路撒冷希伯來大學化學研究所、納米科學與技術中心做博士后研究工作。2015年加入武漢大學化學與分子科學學院，任教授、博導，入選國家青年（2015）。

感測界面、生物分析、功能化納米/生物材料、納米生物技術與納米藥物。包括核酸結構的組裝、調控及應用；納米感測體系的構築與性能研究；功能化生物材料的構建及應用等。相關成果發表在J. Am. Chem. Soc., Angew. Chem. Int. Ed. (VIP論文), ACS Nano, Nano Lett., Adv. Mater., Anal. Chem., Acc. Chem. Res.等國際知名期刊，其中有8篇入選ESI高引用文章，授權專利5項。

歡迎具有化學、生物或材料背景的本科生、研究生和博士后加入我們研究小組。

1.Fuan Wang†, Xiaoqing Liu†, Itamar Willner*, DNA Switches: From Principles to Applications. Angew. Chem. Int. Ed. 2015, 54, 1098-1129. (†Equal Contribution)

2.Xiaoqing Liu, Chun-Hua Lu, Itamar Willner*, Switchable Reconfiguration of Nucleic Acid Nanostructures by Stimuli-Responsive DNA Machines. Acc. Chem. Res. 2014, 47, 1673–1680.

3.Lianzhe Hu†, Xiaoqing Liu†, Alessandro Cecconello, Itamar Willner*, Dual Switchable CRET-Induced Luminescence of CdSe/ZnS Quantum Dots (QDs) by the Hemin/G-Quadruplex-Bridged Aggregation and Deaggregation of Two-Sized QDs. Nano Lett. 2014, 14, 6030-6035. (†Equal Contribution)

4.Fuan Wang, Chun-Hua Lu, Xiaoqing Liu, Lina Freage, Itamar Willner*, Amplified and Multiplexed Detection of DNA Using the Dendritic Rolling Circle Amplified Synthesis of DNAzyme Reporter Units. Anal. Chem. 2014, 86, 1614–1621.

5.Chun-Hua Lu, Xiu-Juan Qi, Xiaoqing Liu, Simcha Shimron, Huang-Hao Yang, Itamar Willner*, Autonomous Control of Interfacial Electron Transfer and the Activation of DNA Machines by an Oscillatory pH System. Nano Lett. 2013, 13, 4920–4924.

6.Xiaoqing Liu, Fuan Wang, Ruth Aizen, Omer Yehezkeli, Itamar Willner*, Graphene Oxide/Nucleic Acid-Stabilized Silver Nanoclusters: Functional Hybrid Materials for Optical Aptamer Sensing and Multiplexed Analysis of Pathogenic DNAs. J. Am. Chem. Soc. 2013, 135, 11832–11839.

7.Fuan Wang, Xiaoqing Liu, Chun-Hua Lu, Itamar Willner*, Cysteine-Mediated Aggregation of Au Nanoparticles: The Development of a H2O2 Sensor and Oxidase-Based Biosensors. ACS Nano, 2013, 7, 7278–7286.

8.Gilad Pelossof, Ran Tel-Vered, Xiaoqing Liu, Itamar Willner*, Switchable Mechanical DNA “Arms” Operating on Nucleic Acid Scaffolds Associated with Electrodes or Semiconductor Quantum Dots. Nanoscale, 2013, 5, 8977–8981.

9.Xiaoqing Liu, Fuan Wang, Angelica Niazov-Elkan, Weiwei Guo, Itamar Willner*, Probing Biocatalytic Transformations with Luminescent DNA/Ag Nanoclusters. Nano Lett. 2013, 13, 309–314.

10.Xiaoqing Liu, Angelica Niazov-Elkan, Fuan Wang, Itamar Willner*, Switching Photonic and Electrochemical Functions of a DNAzyme by DNA Machines. Nano Lett. 2013, 13, 219–225.

11.Fuan Wang, Xiaoqing Liu, Itamar Willner*, Integration of Photoswitchable Proteins, Photosynthetic Reaction Centers and Semiconductor/Biomolecule Hybrids with Electrode Supports for Optobioelectronic Applications. Adv. Mater. 2013, 25, 349–377.

12.Xiaoqing Liu, Ruth Aizen, Ronit Freeman, Omer Yehezkeli, Itamar Willner*, Multiplexed Aptasensors and Amplified DNA Sensors Using Functionalized Graphene Oxide: Application for Logic Gate Operations. ACS Nano 2012, 6, 3553–3563.

13.Xiaoqing Liu, Freeman Ronit, Itamar Willner*, Amplified Fluorescence Aptamer-Based Sensors Using Exonuclease III for the Regeneration of the Analyte. Chem. Eur. J. 2012, 18, 2207–2211.

14.Zhanxia Zhang, Etery Sharon, Ronit Freeman, Xiaoqing Liu, Itamar Willner*, Fluorescence Detection of DNA, Adenosine-5''''''''''''''''''''''''''''''''-Triphosphate and Telomerase Activity by Zn(II)-Protoporphyrin IX/G-Quadruplex as Label. Anal. Chem. 2012, 84, 4789–4797.

15.Ronit Freeman†, Xiaoqing Liu†, Itamar Willner*, Chemiluminescent and Chemiluminescence Resonance Energy Transfer (CRET) Detection of DNA, Metal Ions, and Aptamer-Substrate Complexes Using Hemin/G-Quadruplexes and CdSe/ZnS Quantum Dots. J. Am. Chem. Soc. 2011, 133, 11597–11604. (†Equal Contribution)

16.Xiaoqing Liu, Ronit Freeman, Eyal Golub, Itamar Willner*, Chemiluminescence and Chemiluminescence Resonance Energy Transfer (CRET) Aptamer Sensors Using Catalytic Hemin/G-Quadruplexes. ACS Nano 2011, 5, 7648–7655. DOI:

17.Ronit Freeman, Xiaoqing Liu, Itamar Willner*, Amplified Multiplexed Analysis of DNA by the Exonuclease III-Catalyzed Regeneration of the Target DNA in the Presence of Functionalized Semiconductor Quantum Dots. Nano Lett. 2011, 11, 4456–4461.

18.Gilad Pelossof, Ran Tel-Vered, Xiaoqing Liu, Itamar Willner*, Amplified Surface Plasmon Resonance-Based DNA Biosensors, Aptasensors, and Hg2+ Sensors Using Hemin/G-Quadruplexes and Au Nanoparticles. Chem. Eur. J. 2011, 17, 8904–8912.

19.Xiaoqing Liu, Fuan Wang, Yuling Wang, Shuyun Zhu, Guobao Xu*, Functionalized Single-Walled Carbon Nanohorns for Electrochemical Biosensing. Biosens. Bioelectron. 2010, 25, 2194-2199.

20.Xiaoqing Liu, Fuan Wang, Shuang Han, Lihong Shi, Guobao Xu*, Self-Assembly of gold Nanoparticles/Electroactive Polyelectrolyte Multilayer Films for Tunable Electrocatalysis. Electroanalysis 2010, 22, 963-969.

21.Fuan Wang, Xiaoqing Liu, Gaiping Li, Dan Li, Shaojun Dong*, Selective Electrodissolution of Inorganic Ions/DNA Multilayer Film for Tunable DNA Release. J. Mater. Chem. 2009, 19, 286–291.

22.Wenxin Niu, Shanliang Zheng, Dawei Wang, Xiaoqing Liu, Haijuan Li, Shuang Han, Jiuan Chen, Zhiyong Tang*, Guobao Xu*, Selective Synthesis of Single-Crystalline Rhombic Dodecahedral, Octahedral, and Cubic Gold Nanocrystals. J. Am. Chem. Soc. 2009, 131, 697–703.

23.Xiaoqing Liu, Lihong Shi, Wenxin Niu, Haijuan Li, Guobao Xu*, Amperometric Glucose Biosensor Based on Single-Walled Carbon Nanohorns. Biosens. Bioelectron. 2008, 23, 1887–1890.

24.Xiaoqing Liu, Wenxin Niu, Haijuan Li, Shuang Han, Lihong Shi, Guobao Xu*, Glucose Biosensor Based on Gold Nanoparticle-Catalyzed Luminol Electrochemiluminescence on a Three-Dimensional Sol-Gel Network. Electrochem. Commun. 2008, 10, 1250–1253.

25.Fuan Wang, Jianlong Wang, Xiaoqing Liu, Shaojun Dong*, Nanoparticle-amplified Surface Plasmon Resonance Study of Protein Conformational Change at Interface. Talanta 2008, 77, 628–634.

26.Xiaoqing Liu, Lihong Shi, Wenxin Niu, Haijuan Li, Guobao Xu*, Environmentally Friendly and Highly Sensitive Ruthenium(II) Tris(2,2''''''''''''''''''''''''''''''''-bipyridyl) Electrochemiluminescent System Using 2-(dibutylamino)ethanol as Co-Reactant. Angew. Chem. Int. Ed. 2007, 46, 421–424.

27.Xiaoqing Liu, Lihong Shi, Haijuan Li, Wenxin Niu, Guobao Xu*, Tris(2,2''''''''''''''''''''''''''''''''-bipyridyl)ruthenium(II) Electrochemiluminescent Detection of Coreactants Containing Aromatic Diol Group by the Interaction Between Diol and Borate Anion. Electrochem. Commun. 2007, 9, 2666–2670.

28.Jing Li, Minghua Huang, Xiaoqing Liu, Hui Wei, Yuanhong Xu, Guobao Xu, Erkang Wang*, Enhanced Electrochemiluminescence Sensor from Tris(2,2''''''''''''''''''''''''''''''''-Bipyridyl)Ruthenium(II) Incorporated into MCM-41 and an Ionic Liquid-Based Carbon Paste Electrode. Analyst 2007, 132, 687–691. DOI: 10.1039/B701842H

29.Lihong Shi, Xiaoqing Liu, Haijuan Li, Wenxin Niu, Guobao Xu*, Application of Ceramic Carbon Materials for Solid-Phase Extraction of Organic Compounds. Anal. Chem. 2006, 78, 1345–1348.

30.Lihong Shi, Xiaoqing Liu, Haijuan Li, Guobao Xu*, Electrochemiluminescent Detection Based on Solid-Phase Extraction at Tris(2,2''''''''''''''''''''''''''''''''-Bipyridyl)Ruthenium(II)-Modified Ceramic Carbon Electrode. Anal. Chem. 2006, 78, 7330–7334.

專利：

1.發明人：徐國寶，劉曉慶，史立紅，專利名稱：環境友好的高靈敏電化學發光檢測方法，專利號：200510016848.4，公開號：CN1696666，授權公告日：2010.01.27

2.發明人：徐國寶，史立紅，劉曉慶，牛文新，專利名稱：三聯吡啶釕電化學發光測定血漿鈣的方法，專利號：200510017231.4，公開號：CN1773259，授權公告日：2009.05.20

3.發明人：徐國寶, 史立紅，劉曉慶，李海娟，專利名稱：溶膠－凝膠法製備的碳陶瓷材料的應用，專利號：200510017012.6，公開號：CN1736581，授權公告日：2007.10.10

4.發明人：徐國寶，史立紅，劉曉慶，專利名稱：Nafion－碳陶瓷複合材料電化學發光感測器的製備方法，專利號：CN200510016770.6，公開號：CN1693285，授權公告日：2007.05.09

5.發明人：李景虹，王美佳，劉曉慶，專利名稱：脫氧核糖核酸電化學納米感測器的製備方法，專利號：03127158.8，公開號：CN1525163，授權公告日：2005.08.17