彭貴青

1997.09 - 2001.06，華中農業大學，獸醫專業畢業，學士學位

2001.09 - 2004.06，華中農業大學，預防獸醫學畢業，碩士學位

2004.09 - 2007.06，武漢大學，微生物學專業畢業，理學博士學位

2007.11-2008.10，中國科學院武漢病毒學研究所助理研究員

2009.01-2012.07，美國明尼蘇達大學藥學院博士后

2012.08-至今，華中農業大學“楚天學者特聘教授”（2012），博士生導師，農業微生物學國家重點實驗室固定人員

2022年1月，國務院學位委員會、教育部、人力資源社會保障部印發了《關於全國金融等30個專業學位研究生教育指導委員會換屆的通知》，公布了30個專業學位研究生教育指導委員會新一屆委員名單。動物科學技術學院、動物醫學院彭貴青教授當選全國獸醫專業學位研究生教育指導委員會委員

湖北省晶體學會理事，Journal of Virology、Virology、JGV等雜誌審稿人。

從事分子病毒學及蛋白質結構生物學研究，研究方向包括重要病原體入侵及其與宿主相互作用的分子機理；病原體耐葯分子機理；新型抗病毒藥物和診斷方法的開發與研製。

《動物病毒學》、《細胞生物學C》、《預防獸醫學進展》等。

長期專註於冠狀病毒研究，圍繞該病毒入侵、複製的分子機制，取得一系列具有國際影響的創新性研究成果。先後解析冠狀病毒(MHV、BcoV)刺突蛋白結構、病毒受體(CEACAM1b、PAPN)的結構，以及刺突蛋白與受體複合物（MHV刺突蛋白與受體CEACAM複合物、SARS-CoV刺突蛋白與受體ACE2複合物）的結構；首次發現冠狀病毒刺突蛋白具有凝集素樣結構，闡明了冠狀病毒識別糖受體的分子機理；並且揭示了冠狀病毒與受體共進化的機制。首次解析了動脈炎病毒科PRRSV核酸內切酶NSP11的結構，發現了與冠狀病毒核酸內切酶完全不同的聚合方式，闡明了核酸內切酶參與病毒複製的新機制。承擔有國家自然科學基金、中組部拔尖人才基金、973子課題等科研項目。

近五年，以第一作者或通訊作者在PNAS、Journal of Biological Chemistry、Journal of Virology、Virology等發表SCI論文10篇。

中文論文

[1]彭貴青,李慧,劉一楠.鹽酸考尼伐坦在製備治療貓傳染性腹膜炎藥物中的用途[P].湖北省：CN109364083B,2020-08-18.

[2]劉一楠,陳奕熹,汪剛,毛軍福,彭貴青.貓傳染性腹膜炎診斷研究進展[J].中國動物傳染病學報,,:1-10.

[3]彭貴青,劉紫微.一種由GC376與GS-441524組成的貓冠狀病毒抑製劑組合物[P].湖北省：CN110215456A,2019-09-10.

[4]彭貴青,李慧,劉一楠.鹽酸考尼伐坦在製備治療貓傳染性腹膜炎藥物中的用途[P].湖北省：CN109364083A,2019-02-22.

[5]崔旻,柴本傑,彭貴青,傅振芳,楊宏.一種檢測犬副流感病毒抗體的間接ELISA試劑盒[P].湖北：CN106248937A,2016-12-21.

[6]張歡,肖文婕,曾哲,朱心宇,董楠,彭貴青.豬δ冠狀病毒Nsp5的體外表達及其蛋白酶活性分析[J].中國動物傳染病學報,2016,24(06):6-11.

[7]韋琴,彭貴青,金梅林,朱裕東,周紅波,郭紅燕,陳煥春.雞α干擾素基因的克隆、原核表達及抗病毒效果研究[J].生物工程學報,2006,(05):737-743.

[8]彭貴青,陳煥春,錢平.梅山豬β干擾素基因的克隆、原核表達及生物活性[J].中國獸醫學報,2005,(01):40-42.

[9]彭貴青,陳煥春,錢平,李祥敏,洪琦,顧貧.口蹄疫病毒VP1基因C末端串連表達及其抗體ELISA方法的初步建立[J].畜牧獸醫學報,2004,(06):670-674.

[10]彭貴青.口蹄疫病毒VP1基因C末端及豬α/β干擾素在大腸桿菌中的表達研究[D].華中農業大學,2004.

[11]劉夢元,吳斌,劉建傑,彭貴青,劉國平,陳煥春.規模化豬場大腸桿菌的耐藥性監測及血清流行病學調查[J].中國獸醫學報,2004,(01):16-18.

[12]彭貴青,陳煥春,錢平.口蹄疫診斷技術研究進展[J].動物醫學進展,2003,(06):29-31.

[13]彭貴青,陳煥春,錢平.梅山豬β干擾素的克隆、原核表達及生物活性研究[A].中國畜牧獸醫學會家畜傳染病學分會.中國畜牧獸醫學會家畜傳染病學分會成立20周年慶典暨第十次學術研討會論文集（上）[C].中國畜牧獸醫學會家畜傳染病學分會:中國畜牧獸醫學會,2003:238-240.

[14]彭貴青,陳煥春,錢平.口蹄疫診斷方法最新研究進展[A].中國畜牧獸醫學會家畜傳染病學分會.中國畜牧獸醫學會家畜傳染病學分會成立20周年慶典暨第十次學術研討會論文集（上）[C].中國畜牧獸醫學會家畜傳染病學分會:中國畜牧獸醫學會,2003:530-532.

[15]彭貴青,吳斌,劉夢元.仔豬致病性大腸桿菌分離鑒定及葯敏試驗[A].中國畜牧獸醫學會家畜傳染病學分會.豬的重要傳染病防治研究新成果——中國畜牧獸醫學會家畜傳染病學分會第五屆理事會第二次全體會議暨防檢疫專業委員會第7次學術交流會論文集[C].中國畜牧獸醫學會家畜傳染病學分會:中國畜牧獸醫學會,2002:299-304.

[16]彭貴青,吳斌,劉夢元.仔豬致病性大腸桿菌分離鑒定及葯敏試驗[J].養殖與飼料,2002,(05):29-31.

英文論文

[1]Structure of the Multiple Functional Domains from Coronavirus Nonstructural Protein 3.[J]. Li Mengxia,Ye Gang,Si Yu,Shen Zhou,Liu Zhu,Shi Yuejun,Xiao Shaobo,Fu Zhen F,Peng Guiqing. Emerging microbes & infections.

[2]A novel function of African Swine Fever Virus pE66L in inhibition of host translation by the PKR/eIF2α pathway.[J]. Shen Zhou,Chen Chen,Yang Yilin,Xie Zhenhua,Ao Qingying,Lv Lu,Zhang Shoufeng,Chen Huanchun,Hu Rongliang,Chen Hongjun,Peng Guiqing. Journal of virology.

[3]Coinfection of porcine deltacoronavirus and porcine epidemic diarrhea virus altered viral tropism in gastrointestinal tract in a piglet model[J]. Jiao Zhe,Liang Jixiang,Yang Yilin,Li Yang,Yan Zhishan,Hu Guangli,Gu Changqin,Hu Xueying,Cheng Guofu,Peng Guiqing,Zhang Wanpo. Virology. 2021(prepublish)

[4]The trypsin-enhanced infection of porcine epidemic diarrhea virus is determined by the S2 subunit of the spike glycoprotein.[J]. Tan Yubei,Sun Limeng,Wang Gang,Shi Yuejun,Dong Wanyu,Fu Yanan,Fu Zhen,Chen Huanchun,Peng Guiqing. Journal of virology.

[5]Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes[J]. Song Xiyong,Shi Yuejun,Ding Wei,Niu Tongxin,Sun Limeng,Tan Yubei,Chen Yong,Shi Jiale,Xiong Qiqi,Huang Xiaojun,Xiao Shaobo,Zhu Yanping,Cheng Chongyun,Fu Zhen F.,Liu Zhi Jie,Peng Guiqing. Nature Communications. 2021(1)

[6]The structural basis of African swine fever virus core shell protein p15 binding to DNA[J]. Guo Fenglin,Shi Yuejun,Yang Mengfang,Guo Yilin,Shen Zhou,Li Mengxia,Chen Yixi,Liang Rui,Yang Yilin,Chen Huanchun,Peng Guiqing. The FASEB Journal. 2021(3)

[7]The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract.[J]. Shi Yuejun,Shuai Lei,Wen Zhiyuan,Wang Chong,Yan Yuanyuan,Jiao Zhe,Guo Fenglin,Fu Zhen F,Chen Huanchun,Bu Zhigao,Peng Guiqing. Emerging microbes & infections. 2021(1)

[8]Establishment of Full-length cDNA Clones and an Efficient Oral Infection Model for Feline Coronavirus in Cats.[J]. Wang Gang,Hu Guangli,Liang Rui,Shi Jiale,Qiu Xiuxiu,Yang Yiling,Jiao Zhe,Chen Yixi,Shen Zhou,Li Mengxia,Shi Yuejun,Mao Junfu,Peng Guiqing. Journal of virology.

[9]Genome-scale CRISPR screen identifies TMEM41B as a multi-function host factor required for coronavirus replication.[J]. Sun Limeng,Zhao Changzhi,Fu Zhen,Fu Yanan,Su Zhelin,Li Yangyang,Zhou Yuan,Tan Yubei,Li Jingjin,Xiang Yixin,Nie Xiongwei,Zhang Jinfu,Liu Fei,Zhao Shuhong,Xie Shengsong,Guiqing Peng. PLoS pathogens. 2021(12)

[10]Identification of a novel neutralizing epitope on the N-terminal domain of the HCoV-229E spike protein.[J]. Shi Jiale,Shi Yuejun,Xiu Ruixue,Wang Gang,Liang Rui,Jiao Yuzhou,Shen Zhou,Zhu Chengliang,Peng Guiqing. Journal of virology.

[11]Two Inhibitors Against the 3C-Like Proteases of Swine Coronavirus and Feline Coronavirus.[J]. Zhou Mengxin,Han Yutong,Li Mengxia,Ye Gang,Peng Guiqing. Virologica Sinica. 2021(6)

[12]Glycine 29 Is Critical for Conformational Changes of the Spike Glycoprotein of Mouse Hepatitis Virus A59 Triggered by either Receptor Binding or High pH[J]. Dan Mi,Xiuyuan Ou,Pei Li,Guiqing Peng,Yan Liu,Ruixuan Guo,Zhixia Mu,Fang Li,Kathryn Holmes,Zhaohui Qian. Journal of Virology. 2019(20)

[13]Susceptibility of porcine IPI-2I intestinal epithelial cells to infection with swine enteric coronaviruses[J]. Xunlei Wang,Liurong Fang,Shudan Liu,Wenting Ke,Dang Wang,Guiqing Peng,Shaobo Xiao. Veterinary Microbiology.

[14]Porcine deltacoronavirus nsp15 antagonizes interferon-β production independently of its endoribonuclease activity[J]. Xiaorong Liu,Puxian Fang,Liurong Fang,Yingying Hong,Xinyu Zhu,Dang Wang,Guiqing Peng,Shaobo Xiao. Molecular Immunology. 2019(C)

[15]The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in Piglets[J]. Gang Wang,Rui Liang,Ziwei Liu,Zhou Shen,Jiale Shi,Yuejun Shi,Feng Deng,Shaobo Xiao,Zhen F. Fu,Guiqing Peng. Viruses. 2019(4)

[16]Two critical N-terminal epitopes of the nucleocapsid protein contribute to the cross-reactivity between porcine epidemic diarrhea virus and porcine transmissible gastroenteritis virus.[J]. Xie Wenting,Ao Chaojie,Yang Yilin,Liu Yinan,Liang Rui,Zeng Zhe,Ye Gang,Xiao Shaobo,Fu Zhen F,Dong Wanyu,Peng Guiqing. The Journal of general virology. 2019(2)

[17]Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-β production by impairing dsRNA and PACT binding to RIG-I.[J]. Jun Chen,Puxian Fang,Mohan Wang,Qi Peng,Jie Ren,Dang Wang,Guiqing Peng,Liurong Fang,Shaobo Xiao,Zhen Ding. Virus genes. 2019(4)

[18]A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence.[J]. Shen Zhou,Wang Gang,Yang Yiling,Shi Jiale,Fang Liurong,Li Fang,Xiao Shaobo,Fu Zhen F,Peng Guiqing. The Journal of biological chemistry. 2019(37)

[19]Crystal structures of Babesia microti lactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis.[J]. Yu Long,Shen Zhou,Liu Qin,Zhan Xueyan,Luo Xiaoyin,An Xiaomeng,Sun Yali,Li Muxiao,Wang Sen,Nie Zheng,Ao Yangsiqi,Zhao Yangnan,Peng Guiqing,Mamoun Choukri Ben,He Lan,Zhao Junlong. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019(12)

[20]Porcine Deltacoronavirus Accessory Protein NS6 Antagonizes Interferon Beta Production by Interfering with the Binding of RIG-I/MDA5 to Double-Stranded RNA[J]. Puxian Fang,Liurong Fang,Jie Ren,Yingying Hong,Xiaorong Liu,Yunyang Zhao,Dang Wang,Guiqing Peng,Shaobo Xiao. Journal of Virology. 2018(15)

[21]Crystal Structure of the Dimerized N Terminus of Porcine Circovirus Type 2 Replicase Protein Reveals a Novel Antiviral Interface[J]. Gao Luo,Xiongfei Zhu,Yang Lv,Bomin Lv,Jin’e Fang,Shengbo Cao,Huanchun Chen,Guiqing Peng,Yunfeng Song. Journal of Virology. 2018(18)

[22]Dimerization of Coronavirus nsp9 with Diverse Modes Enhances Its Nucleic Acid Binding Affinity[J]. Zhe Zeng,Feng Deng,Ke Shi,Gang Ye,Gang Wang,Liurong Fang,Shaobo Xiao,Zhenfang Fu,Guiqing Peng. Journal of Virology. 2018(17)

[23]Identification of two antiviral inhibitors targeting 3C-like serine/3C-like protease of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus[J]. Yuejun Shi,Yingying Lei,Gang Ye,Limeng Sun,Liurong Fang,Shaobo Xiao,Zhen F. Fu,Ping Yin,Yunfeng Song,Guiqing Peng. Veterinary Microbiology.

[24]Contribution of porcine aminopeptidase N to porcine deltacoronavirus infection.[J]. Zhu Xinyu,Liu Shudan,Wang Xunlei,Luo Zhaochen,Shi Yuejun,Wang Dang,Peng Guiqing,Chen Huanchun,Fang Liurong,Xiao Shaobo. Emerging microbes & infections. 2018(1)

[25]Insight into the evolution of nidovirus endoribonuclease based on the finding that nsp15 from porcine Deltacoronavirus functions as a dimer.[J]. Zheng Anjun,Shi Yuejun,Shen Zhou,Wang Gang,Shi Jiale,Xiong Qiqi,Fang Liurong,Xiao Shaobo,Fu Zhen F,Peng Guiqing. The Journal of biological chemistry. 2018(31)

[26]Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2[J]. Xinyu Zhu,Dang Wang,Junwei Zhou,Ting Pan,Jiyao Chen,Yuting Yang,Mengting Lv,Xu Ye,Guiqing Peng,Liurong Fang,Shaobo Xiao. Journal of Virology. 2017(10)

[27]Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1[J]. Shen Zhou,Ye Gang,Deng Feng,Wang Gang,Cui Min,Fang Liurong,Xiao Shaobo,Fu Zhen F.,Peng Guiqing. Journal of Virology. 2017(5)

[28]Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor.[J]. Peng Guiqing,Yang Yang,Pasquarella Joseph R,Xu Liqing,Qian Zhaohui,Holmes Kathryn V,Li Fang. The Journal of biological chemistry. 2017(6)

[29]Identification and Comparison of Receptor Binding Characteristics of the Spike Protein of Two Porcine Epidemic Diarrhea Virus Strains[J]. Feng Deng,Gang Ye,Qianqian Liu,Muhammad Tariq Navid,Xiaoli Zhong,Youwen Li,Chunyun Wan,Shaobo Xiao,Qigai He,Zhen F. Fu,Guiqing Peng. Viruses. 2016(3)

[30]Structural basis for the dimerization and substrate recognition specificity of porcine epidemic diarrhea virus 3C-like protease[J]. Gang Ye,Feng Deng,Zhou Shen,Rui Luo,Ling Zhao,Shaobo Xiao,Zhen F. Fu,Guiqing Peng. Virology.

[31]Rabies virus phosphoprotein interacts with ribosomal protein L9 and affects rabies virus replication[J]. Youwen Li,Wanyu Dong,Yuejun Shi,Feng Deng,Xi Chen,Chunyun Wan,Ming Zhou,Ling Zhao,Zhen F. Fu,Guiqing Peng. Virology.

[32]Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation.[J]. Sui Baokun,Huang Junhua,Jha Babal K,Yin Ping,Zhou Ming,Fu Zhen F,Silverman Robert H,Weiss Susan R,Peng Guiqing,Zhao Ling. The Journal of general virology. 2016(4)

[33]A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of Porcine Reproductive and Respiratory Syndrome Virus nsp11.[J]. Shi Yuejun,Li Youwen,Lei Yingying,Ye Gang,Shen Zhou,Sun Limeng,Luo Rui,Wang Dang,Fu Zhen F,Xiao Shaobo,Peng Guiqing. Journal of virology. 2016(9)

[34]Comparison of lentiviruses pseudotyped with S proteins from coronaviruses and cell tropisms of porcine coronaviruses.[J]. Wang Jingjing,Deng Feng,Ye Gang,Dong Wanyu,Zheng Anjun,He Qigai,Peng Guiqing. Virologica Sinica. 2016(1)

[35]Porcine Epidemic Diarrhea Virus 3C-Like Protease Regulates Its Interferon Antagonism by Cleaving NEMO.[J]. Wang Dang,Fang Liurong,Shi Yanling,Zhang Huan,Gao Li,Peng Guiqing,Chen Huanchun,Li Kui,Xiao Shaobo. Journal of virology. 2016(4)

[36]Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus.[J]. Fang Jin’e,Li Huan,Kong Dexin,Cao Shengbo,Peng Guiqing,Zhou Rui,Chen Huanchun,Song Yunfeng. Scientific reports. 2016(11)

[37]Glycoprotein E2 of classical swine fever virus expressed by baculovirus induces the protective immune responses in rabbits[J]. Huawei Zhang,Xiangmin Li,Guiqing Peng,Chenkai Tang,Shixuan Zhu,Suhong Qian,Jinfang Xu,Ping Qian. Vaccine. 2014(49)

[38]Methods for detecting ATP hydrolysis and nucleic acid unwinding of Japanese encephalitis virus NS3 helicase[J]. Jin’e Fang,Huan Li,Guiqing Peng,Shengbo Cao,F. Fu Zhen,Huanchun Chen,Yunfeng Song. Journal of Virological Methods. 2013(1-2)

[39]Identification of three antiviral inhibitors against Japanese encephalitis virus from library of pharmacologically active compounds 1280.[J]. Fang Jin’e,Sun Leqiang,Peng Guiqing,Xu Jia,Zhou Rui,Cao Shengbo,Chen Huanchun,Song Yunfeng. PloS one. 2013(11)

[40]Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376[J]. Gang Ye,Xiaowei Wang,Xiaohan Tong,Yuejun Shi,Zhen F. Fu,Guiqing Peng. Viruses. 2020(2)

[41]Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion[J]. Zhou Shen,Yiling Yang,Siqi Yang,Guangxu Zhang,Shaobo Xiao,Zhen F. Fu,Guiqing Peng. Viruses. 2020(8)

[42]Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.[J]. Shang Jian,Wan Yushun,Liu Chang,Yount Boyd,Gully Kendra,Yang Yang,Auerbach Ashley,Peng Guiqing,Baric Ralph,Li Fang. PLoS pathogens. 2020(3)

[43]Lysine 164 is critical for SARS-CoV-2 Nsp1 inhibition of host gene expression[J]. Shen Zhou,Zhang Guangxu,Yang Yilin,Li Mengxia,Yang Siqi,Peng Guiqing. Journal of General Virology.

[44]Rapid manipulation of the porcine epidemic diarrhea virus genome by CRISPR/Cas9 technology[J]. Qi Peng,Liurong Fang,Zhen Ding,Dang Wang,Guiqing Peng,Shaobo Xiao. Journal of Virological Methods. 2020(C)

[45]Receptor tyrosine kinase inhibitors block proliferation of TGEV mainly through p38 mitogen-activated protein kinase pathways[J]. Wanyu Dong,Wenting Xie,Yunbo Liu,Baokun Sui,Hao Zhang,Liran Liu,Yubei Tan,Xiaohan Tong,Zhen F. Fu,Ping Yin,Liurong Fang,Guiqing Peng. Antiviral Research. 2020(C)

[46]Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development.[J]. Liang Rui,Wang Gang,Zhang Ding,Ye Gang,Li Mengxia,Shi Yuejun,Shi Jiale,Chen Huanchun,Peng Guiqing. The Journal of biological chemistry.

[47]Structural Characterization of the Helicase Nsp10 Encoded by Porcine Reproductive and Respiratory Syndrome Virus[J]. Yuejun Shi,Xiaohan Tong,Gang Ye,Ruixue Xiu,Lisha Li,Limeng Sun,Jiale Shi,Mengxia Li,Yunfeng Song,Chengpeng Fan,Ke Shi,Zhen F. Fu,Shaobo Xiao,Guiqing Peng. Journal of Virology. 2020(15)

[48]Shen Z, Ye G, Deng F, Wang G, Cui M, Fang L, Xiao S, Fu ZF, Peng G*.Structural basis for the inhibition of host gene expression by porcine epidemic diarrhea virus nsp1. J Virol.（in press）

[49]Shi Y, Lei Y, Ye G, Sun L, Fang L, Xiao S, Fu ZF, Yin P, Song Y*, Peng G*. Identification of Two Antiviral Inhibitors Targeting 3C-like Serine/3C-like Protease of Porcine Reproductive and Respiratory Syndrome Virus and Porcine Epidemic Diarrhea Virus. Veterinary Microbiology. Volume 213, January 2018, Pages 114–122

[50]Zeng Z, Li TT, Jin X, Peng FH, Song NH, Peng GQ*, Ge XY*. Coexistence of multiple genotypes of porcine epidemic diarrhea virus with novel mutant S genes in the Hubei Province of China in 2016. Virol Sin. 2017 Aug;32(4):298-306.

[51]Zhu X, Wang D, Zhou J, Pan T, Chen J, Yang Y, Lv M, Ye X, Peng G, Fang L, Xiao S. Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2. J Virol. 2017 Apr 28;91(10). pii: e00003-17.

[52]Peng G, Yang Y, Pasquarella JR, Xu L, Qian Z, Holmes KV, Li F.Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor. J Biol Chem. 2017 Feb 10;292(6):2174-2181.

[53]Fang J, Li H, Kong D, Cao S, Peng G, Zhou R, Chen H, Song Y.Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus. Sci Rep. 2016 Sep 29;6:34550.

[54]Ye G, Deng F, Shen Z, Luo R, Zhao L, Xiao S, Fu ZF, Peng G*. Structural basis for the dimerization and substrate recognition specificity of porcine epidemic diarrhea virus 3C-like protease. Virology. 2016 Jul;494:225-35.

[55]Shi Y, Li Y, Lei Y, Ye G, Shen Z, Sun L, Luo R, Wang D, Fu ZF, Xiao S, Peng G*. A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of PRRSV nsp11. J Virol. 2016 Feb 24. pii: JVI.03065-15.

[56]Wang J, Deng F, Ye G, Dong W, Zheng A, He Q, Peng G*. Comparison of lentiviruses pseudotyped with S proteins from coronaviruses and cell tropisms of porcine coronaviruses. Virol Sin. 2016 Feb;31(1):49-56.

[57]Deng F, Ye G, Liu Q, Navid MT, Zhong X, Li Y, Wan C, Xiao S, He Q*, Fu ZF*, Peng G*. Identification and Comparison of Receptor Binding Characteristics of the Spike Protein of Two Porcine Epidemic Diarrhea Virus Strains. Viruses. 2016 Feb 23;8(3). pii: E55.

[58]Sui B, Huang J, Jha BK, Yin P, Zhou M, Fu ZF, Silverman RH, Weiss SR, Peng G*, Zhao L*. Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation. J Gen Virol. 2016 Jan 12.

[59]Li Y, Dong W, Shi Y, Deng F, Chen X, Wan C, Zhou M, Zhao L, Fu ZF*, Peng G*. Rabies virus phosphoprotein interacts with ribosomal protein L9 and affects rabies virus replication. Virology. 2016 Jan 15;488:216-24.

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1.國家自然科學基金優青(No.31722056) 2018-2020

2.國家自然科學基金面上(No.31372440)2014-2017

3.中組部青年拔尖人才2015-2018

4.973項目(2014CB542700)骨幹2014-2018

5.湖北省自然科學基金重點項目2017-2019

6.教育部新教師基金(No.4010-131011)2013-2015

7.湖北省基金面上（No.4006-36113009)2013-2015

8.創新群體研究骨幹2014-2018

9.微生物國家重點實驗室2012-2017

10.楚天學者特聘教授啟動基金2012-2017

11.校傑青培植基金2015-2017

12.自主科技創新基金(No.2013PY031）2013-2015

曾獲第十三屆湖北省自然科學優秀學術論文一等獎，第七屆國際病毒學會Christophe Meriux 獎。

1.第十三屆湖北省自然科學優秀學術論文一等獎。

2.第七屆國際病毒學會Christophe Meriux獎。

3.國家“萬人計劃”青年拔尖人才。

4.教育部青年長江學者。

5.國家自然科學基金“優青”獲得者。

6.科技部中青年領軍人才