劉鈺

教育背景

1999.09－2002.07 中國科學院成都有機化學研究所，生物醫學專業，博士學位

1996.09－1999.07 四川大學，高分子物理專業，碩士學位

1991.09－1995.07 四川大學，高分子材料專業，學士學位

工作履歷

2010.10~ present 電子科技大學微電子與固體電子學院，副教授

2006.10－2010.09 Philipps-University Marburg, Germany, 博士后

2004.07－2006.07 中國科學院成都有機化學研究所，副研究員

2002.08－2004.07 中國科學院成都有機化學研究所，博士后

學術兼職

中國生物材料協會會員

美國化學學會會員

研究方向：生物電子與生物醫學

研究內容1

超分子結構材料的設計、製備與性能研究；超分子結構材料在新能源，生物醫學及生物電子中的應用；

研究內容2

生物感測器的設計及製備；生物醫學檢測技術及其輔助治療技術的研究；

研究內容3

納米有序材料的設計與製備；分子有序結構的組裝；分子/納米器件；生物納米材料的設計及在生物醫學和生物電子中的應用

部分代表性論文：

1. Xianmo Deng,Yu Liu, Minglong Yuan, Study on biodegradable polymers. 3 synthesis and characterization of poly (DL-lactide acid)-poly-(ethylene glycol)-co-L-lysine) block copolymer. Eur. Polym. J. 2002. 38 (7), 1435. (通訊作者)

2. Xianmo Deng,Yu Liu,Xiaohong Li, Wenxiang Jia. Preparation and characterization of poly-DL-lactide-poly (ethylene glycol) microspheres containning lambda DNA. J. Appl. Polym. Sci.2002 .86 (10), 2557-2566, （通訊作者）

3.Yu Liu,Xianmo Deng, Xiaohong Li. Influence of preparation conditions on particle size and DNA loading efficiency for poly-DL-lactide-co-poly (ethylene glycol) microspheres entrapping free DNA. J. Control. Release. 2002. 83(1), 147-155.

4.Yu Liu,Minglong Yuan, Xianmo Deng. Study on biodegradable polymers: synthesis and characterization of poly (DL-lactide acid-co-L-lysine) random copolymer. Eur. Polym. J.,2003，39(5), 977-983.

5.Yu liu,Li Kun Guo, Long Huang, X M Deng. Preparation and properties of biodegradable polymer as a novel drug delivery system. J. Appl. Polym. Sci. 2003，90(11), 3150-3156.

6. Jian Yuan Hao,Yu Liu,Shaobing Zhou, Zhen Li, Xianmo Deng. Investigation of nanocomposities based on semi-interpenetrating network of [L-poly (ε-caprolactone)] and hydroxyapatite nanocrystals. Biomaterials.2003，20 (9), 1531-1539.

7. Likun Guo,Yu Liu, Xianmo Deng, Jianyuan Hao. The degradation of biodegradable polymer in different pH values and accelerated degradation by increasing temperature or performing in 6% H2O2-PBS solution. Journal of Polymer Materials.2003. 20(3), 285-291.

8.Yu Liu, Long Huang, Xiao Rong Qiao, Xianmo Deng, Xiaohong Li. Investigation of poly-DL-lactide-co-poly (ethylene glycol) microspheres containing plasmid DNA. Chinese J. Polym.Sci.2004. 3, 205~214

9. Long Huang, Aiping Zhang,Yu Liu. Investigation of the relationship between chronic obstructive pulmonary disease and the values of TNFα in the sputum . China J. Clinic New Theory Medical Science,2005. 9(1), 27-29.

10. Long Huang,Yu Liu, Yuqiong Zheng. Investigation of the relationship between chronic obstructive pulmonary disease and the values of TNF and IL-8 in the sputum. Chinese Modern Medical and Clinical,2005. 4 (3), 20-21.

11. Hui Miao, Ying Fan, Yan Liu,Yu Liu,Jianyuan Hao and Xianmo Deng. Biodegradable poly(sebacic anhydride-co-caprolactone) multi-block copolymers: Synthesis, characterization, crystallinity and crystalline morphology, Eur. Polym. J.2007. 43(3), 1055-1064.

12.Zhiqiang Jiang. Jianyuan. Hao, Y. You,Yu Liu, Z Wang. Xianmo Deng, 2008, Biodegradable and the thermoreversible hydrogels of poly (ethylene glycol) –poly (epsilon- caprolactone -co- glycolide)-poly (ethylene glycol) aqueous solutions. J. Biomed. Mater. Res. A 2008, 87(1), 45-51.

13.Yu. Liu,J. Nguyen, T. Steele, O. Merkel, Thomas Kissel. A new synthesis method and degradation of hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymers (hy-PEI-g-PCL-b-mPEG) as potential gene delivery vectors, Polymer,2009, 50(16), 3895-3904.

14.Yu Liu,Terry Steele, Thomas Kissel. Degradation of hyper-branched poly (ethylenimine)-g-poly(caprolactone)-b-mono-methoxyl-poly(ethylene glycol) as a Potential Gene Delivery Vector. Macro. Rap. Com.2010, 31（17），1509-1515.

15.Yu Liu, Annette Kemmer, Klaus Keim, Catherine Curdy, Holger Petersen Thomas Kissel. Poly(ethylene carbonate) as a biomaterial for biodegradable in-situ forming parenteral drug delivery systems: A feasibility study. Eur. J. Pharm. Biopharm.2010, 76（2）222-229.

16. Yuan Yang, Yu Kuang,Yu Liu,Wangyi Li, Zhonghua Jiang, Liying Xiao, Mingyuan Li, Immunogenicity of mutiple-epitope antigen gene of HCV carried by novel biodegradable polymers. Comparative Immnuology, Microbiology & Infectious Diseases,2011, 34 (1), 65-72.

17.Yu Liu,Olivia Merkel, Terry Steele, Thomas Kissel, Biophysical characterization of hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymer (hy-PEI-g-PCL-b-mPEG) for siRNA delivery, J. control. Release,2011, 153(3),262-268.

18. Mengyao Zheng,Yu Liu ( contributed equally),Olga Samsonova, Thomas Endres, Olivia Merkel, Thomas Kissel, Amphiphilic and biodegradable hy-PEI-g-PCL-b-PEG copolymers efficiently mediate transgene expression depending on their graft density,Int. J. Pharm. ,2012, 427(1), 80-87.

19. Mengyao Zheng, Damiano Librizzi b, Ays¸ e Kılıç,Yu Liu,Harald Renz, Olivia Merkel, Thomas Kissel, Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers, Biomaterials, 2012,33,6551-6558.

20. Tianqiang Wang, Jianyuan Hao,Yu Liu, Zhongwei Gu, “Formation of well-defined spherical particles during suspension polymerization of biodegradable poly(glycolide-co-p-dioxanone) in supercritical carbon dioxide”, RSC Advances,2012, 2, 10365-10371.

21. Huizhen Zhao, Tianqiang Wang, Xiuli Zhao,Yu Liu, Jianyuan Hao, “Synthesis and properties of poly(d,l-lactide-co-p-dioxanone) random and segmented copolymers”, Journal of Polymers and the Environment,2012, 10.1007/s10924-012-0526-2.

22. Lei Feng，Yu Liu，Jianyuan Hao，et al, “Alternating copolymers with degradability and quantitatively controlled thermosensitivity”, Journal of Polymer Science Part A: Polymer Chemistry, 2012, 9, 1812-1818.

23. Tianqiang Wang, Jing Ding, Xiuli Zhao,Yu Liu, Jianyuan Hao, “In-situ suspension polymerization of poly(L-lactide-co-p-dioxanone) in supercritical carbon dioxide”, Journal of Polymers and the Enviroment,2012, 20(1), 157-163.

24. Lei Feng，Yu Liu，Jianyuan Hao，et al, “Synthesis and properties of novel thermoresponsive polyesters with oligo(ethylene glycol) pendent chains”, Macromolecular Chemistry and Physics, 2011, 212(24), 2626-2632.