王澈

2009.8～至今遼寧師範大學化學化工學院副教授。

2005.7～2009.7遼寧師範大學化學化工學院講師。

2001.9～2005.6瀋陽藥科大學藥學院藥理系碩博連讀獲理學博士學位。

1997.9～2001.7瀋陽藥科大學藥學院國家(藥學)理科基地獲理學學士學位。

研究生教學:藥理學前沿。

本科生教學:生物化學，藥理學，藥學概論，免疫學。

1參與國家自然科學基金項目《兩棲類皮膚膜活性肽α-MAPs選擇性阻抑乳腺癌MCF-7細胞生長的分子機制研究》，金額32萬，項目編號30970352，起止時間2010年1月-2012年12月，負責活性肽的抗癌作用機制研究。

2參與國家自然科學基金項目《具有抑制脲酶活性的新化合物的分子設計、研製與性能研究》，金額18萬，項目編號20901036，起止時間2010年1月-2012年12月，負責生物活性檢測工作。

3參與國家自然科學基金項目《聚吡唑硼酸鹽類釩氧配合物設計、合成、結構與生物活性研究》，（20771051），2008年1月-2010年12月，負責生物活性檢測部分工作。

在國內外刊物上發表論文20餘篇，其中SCI收載10篇；發表論文曾獲遼寧省自然科學學術成果二等獎、三等獎各一項和大連市自然科學優秀學術論文三等獎兩項；指導在研研究生3人。

1.Che WANG, Min-wei WANG, Shin-ichi TASHIRO, Satoshi ONODERA, and Takashi IKEJIMA. Roles of SIRT1 and phosphoinositide 3-OH kinase (PI3-K)/protein kinase C (PKC) pathways in evodiamine-induced human melanoma A375-S2 cell death. J Pharmacol Sci. 2005; 97 (4): 494-500.

2.Che WANG, Min-wei WANG, Shin-ichi TASHIRO, Satoshi ONODERA, and bTakashi IKEJIMA. IL-1 in A375-S2 human melanoma cell apoptosis bacts in synergy with endogenous IL-1 through mitochondrial pathway. J Korean Med Sci. 2005; 20 (4): 555-561.

3.Che WANG, Min-wei WANG, Shin-ichi TASHIRO, Satoshi ONODERA, and Takashi IKEJIMA. Evodiamine induced human melanoma A375-S2 cell death partially through interleukin 1 mediated pathway. Biol Pharm Bull. 2005; 28 (6): 984-989.

4.Che WANG, Song Li, Min-wei WANG. Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition. Toxicology In Vitro. 2009 Dec 11. Epub ahead of print

5. Song Li,Che Wang, Wei Li, Kazuo Koike, Tamatsu Nikaido, Min -Wei Wang. Antidepressant-like effects of piperine and its derivative, antiepilepsirine. Journal of Asian Natural Product Research. 2007, 9(5): 421-430.

6. Song LI,Che WANG, Min-wei WANG, et al. Impairment of the spatial learning and memory induced by learned helplessness and chronic mild stress. Pharmacology, Biochemistry and Behavior. 2006, 83: 186-193.

7. Song LI,Che WANG, Minwei WANG, Wei LI, Kinzo MATSUMOTO, Yiyuan TANG. Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms. Life sciences 2007,80 (15): 1373-1381.

8. Song Li,Che Wang, Wei Wang, Huiping Dong, Peng Hou, Yiyuan Tang. Chronic mild stress impairs cognition in mice: from brain homeostasis to behavior. Life Sciences. 2008,82 (17-18): 934-942.

9. Peng HOU, Zhong-lu YOU,Che WANG. Synthesis, Crystal Structure, and Cytochrome P450-Like Hydroxylation Property of a Novel Azido-Bridged Manganese(III) Complex Derived from 2-[(2-Phenylaminoethylimino)Methyl] Phenol. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2008, 38: 677?80.

10. Zhong-lu YOU, Peng HOU,Che WANG. Syntheses and crystal structures of two copper(II) complexes derived from 2-bromo-4-chloro-6-[(2-morpholin-4-ylethylimino)methyl]phenol. Journal of Coordination Chemistry. 2009, 62: 593?/span>599.