任國棟

B.S., Fudan University, 2000; Ph.D., Fudan University, 2009.

Postdoc, University of Nebraska-Lincoln, 2009-2013.

PI, Fudan University, Since 2013

綜合運用正反向遺傳學, 生物化學，細胞生物學及分子生物學等實驗技術手段結合下一代高通量測序技術研究植物小分子RNA代謝與功能的分子基礎。主要開展以下幾方面的研究：

1）植物小分子RNA代謝的分子基礎；

2）植物小分子RNA介導的DNA甲基化；

3）小分子RNA在植物生長發育和抵抗非生物逆境中的功能；

男，1981年出生，博士，研究員。

2004年獲復旦大學學士學位

2009年獲復旦大學大學生物化學與分子生物學博士學位

2009至2013年在內布拉斯加州大學林肯分校從事博士后研究，

2013年11月起受聘復旦大學生命科學學院青年研究員，

2014年12月起晉陞為研究員。

2014年中組部“青年千人“計劃

2016年，國家優秀青年基金

1，Wang X#, Wang Y#, Dou Y#, Chen L, Wang J, Jiang N, Guo C, Yao Q, Wang C, Liu L, Yu B, Zheng B, Chekanova JA, Ma J, Ren G*(2018) Degradation of unmethylated miRNA/miRNA*s by a DEDDy-type 3’ to 5’ exoribonuclease ATRIMMER2 in Arabidopsis. Proc Natl Acad Sci USA，115 (28), E6659-E6667

2，Li Z, Wu S, Chen J, Wang X, Gao J, Ren G*and Kuai B* (2017), NYEs/SGRs-Mediated Chlorophyll Degradation is Critical for Detoxification during Seed Maturation in Arabidopsis. Plant Jdoi:10.1111/tpj.13710

3, Wu S#, Li Z#, Yang L, Xie, Z, Chen J, Zhang W, Liu T, Gao S, Gao J, Zhu Y, Xin J, Ren G*, Kuai B* (2016) NON-YELLOWING2 (NYE2), a close paralog of NYE1, plays a positive role in chlorophyll degradation in Arabidopsis. Mol Plant. 9(4), 624-627

4, Wang X#, Zhang S#, Dou Y#, Zhang C, Chen X, Yu B*, Ren G*(2015) Synergistic and independent actions of multiple terminal nucleotidyl transferases in 3’ tailing of small RNAs in Arabidopsis. PLoS Genet11(4): e1005091.

5, Ren G*, Chen X, Yu B* (2014) Small RNAs meet their targets: when methylation defends miRNAs from uridylation. RNA Biol.11(9):1099-104（Invited Review）

6, Ren G#, Xie M#, Zhang S, Vinovskis C, Chen X and Yu B* (2014) Methylation protects miRNAs from an AGO1-associated activity that uridylates 5' RNA fragments generated by AGO1 cleavage Proc Natl Acad Sci USA111 (17), 6365-6370

7, Ren G, Chen X, Yu B* (2012) Uridylation of miRNAs by HEN1 SUPPRESSOR1 in Arabidopsis. Curr Biol 22(8): 695-700

8, Ren G, Xie M, Dou Y, Zhang S, Zhang C, Yu B* (2012) Regulation of small RNA abundance by TOUGH in Arabidopsis. Proc Natl Acad Sci USA109(31): 12817-12821

9, Xie M#, Ren G#, Zhang C, Yu B* (2012) The DNA and RNA binding protein FACTOR of DNA METHYLATION 1 requires XH domain-mediated complex formation for its function in RNA-directed DNA methylation. Plant J72, 491–500

10, Ren G, An K, Liao Y, Zhou X, Cao Y, Zhao H, Ge X, Kuai B* (2007) Identification of a Novel Chloroplast Protein Regulating Chlorophyll Degradation during Leaf Senescence in Arabidopsis. Plant Physiol144: 1429-1441