孕酮受體
孕酮受體
孕酮受體(英語:progesterone receptor,縮寫PR,也被稱為NR3C3,nuclear receptor subfamily 3, group C, member 3,即核受體第三亞族C組成員3)是一種細胞內蛋白質,由甾體激素孕酮激活。
目錄
Progesterone receptor 孕酮受體 | |||
PDBrendering based on 1a28. | |||
有效結構 PDB直系同源檢索:PDBe,RCSB |
[隱藏]PDB查詢代碼列表 | |||
標識 | |||
代號 | PGR; NR3C3; PR | ||
擴展標識 | 遺傳學:607311鼠基因:97567同源基因:713IUPHAR: ChEMBL:208GeneCards:PGR Gene | ||
[隱藏]基因本體論描述 分子功能·DNA binding ·steroid hormone receptor activity ·ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ·receptor binding ·steroid binding ·protein binding ·zinc ion binding ·enzyme binding ·sequence-specific DNA binding 細胞成分·nucleus ·nucleoplasm ·nucleolus ·cytoplasm ·intracellular membrane-bounded organelle 生物過程·ovulation from ovarian follicle ·epithelial cell maturation ·transcription initiation from RNA polymerase II promoter ·signal transduction ·cell-cell signaling ·gene expression ·negative regulation of gene expression ·regulation of epithelial cell proliferation ·progesterone receptor signaling pathway ·tertiary branching involved in mammary gland duct morphogenesis Sources:Amigo/QuickGO | |||
RNA表達模式 | |||
更多表達數據 | |||
直系同源體 | |||
物種 | 人類 | 鼠類 | |
Entrez | 5241 | 18667 | |
Ensembl | ENSG00000082175 | ENSMUSG00000031870 | |
UniProt | P06401 | n/a | |
mRNA序列 | NM_000926 | NM_008829 | |
蛋白序列 | NP_000917 | NP_032855 | |
基因位置 | Chr 11: 100.9 – 101 Mb | Chr 9: 8.9 – 8.97 Mb |