孕酮受體

孕酮受體

孕酮受體(英語:progesterone receptor,縮寫PR,也被稱為NR3C3,nuclear receptor subfamily 3, group C, member 3,即核受體第三亞族C組成員3)是一種細胞內蛋白質,由甾體激素孕酮激活。

目錄

正文


Progesterone receptor 孕酮受體
PDBrendering based on 1a28.
有效結構
PDB直系同源檢索:PDBe,RCSB
[隱藏]PDB查詢代碼列表
1A28,1E3K,1SQN,1SR7,1ZUC,2C7A,2OVH,2OVM,2W8Y,3D90,3G8O,3HQ5,3KBA,3ZR7,3ZRA,3ZRB,4A2J,4APU
標識
代號PGR; NR3C3; PR
擴展標識遺傳學:607311鼠基因:97567同源基因:713IUPHAR: ChEMBL:208GeneCards:PGR Gene
[隱藏]基因本體論描述
分子功能·DNA binding
·steroid hormone receptor activity ·ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ·receptor binding ·steroid binding ·protein binding ·zinc ion binding ·enzyme binding
·sequence-specific DNA binding
細胞成分·nucleus
·nucleoplasm ·nucleolus ·cytoplasm
·intracellular membrane-bounded organelle
生物過程·ovulation from ovarian follicle
·epithelial cell maturation ·transcription initiation from RNA polymerase II promoter ·signal transduction ·cell-cell signaling ·gene expression ·negative regulation of gene expression ·regulation of epithelial cell proliferation ·progesterone receptor signaling pathway
·tertiary branching involved in mammary gland duct morphogenesis
Sources:Amigo/QuickGO
RNA表達模式
更多表達數據
直系同源體
物種人類鼠類
Entrez524118667
EnsemblENSG00000082175ENSMUSG00000031870
UniProtP06401n/a
mRNA序列NM_000926NM_008829
蛋白序列NP_000917NP_032855
基因位置
Chr 11:
100.9 – 101 Mb
Chr 9:
8.9 – 8.97 Mb