謝鵬

1995~1996年，留學日本濱松醫科大學神經精神科和日本福島醫科大學微生物教研室，擔任客座研究員。

歷任重慶醫科大學附屬第一醫院神經內科助教、住院醫師、講師、主治醫師、教授、附屬第一醫院副院長、重慶醫科大學校長助理。

2004年9月起任重慶醫科大學副校長。

近5年先後發表專業學術論文2多篇，參編專著10餘部。

主持“BDV人體感染模型初探及病毒性腦炎的生物學診斷”、“活體MRI追蹤腦內移植磁標記神經幹細胞的實驗研究”、“博爾納病病毒的分子流行病學研究”、“抑鬱症發病機制的功能磁共振和蛋白質組學研究”四項國家自然科學基金課題，以及衛生部科學基金、教育部博士點基金和人事部歸國人員基金各1項，以及重慶市科技攻關課題等共10多項科研課題。

先後負責已結題國家重大科學研究計劃“973“項目和國家”863“目標導向項目各1項、國家自然科學基金6項、省部級等各類基金14項，共獲准科研經費3380餘萬元。現已發表學術論文200餘篇，其中SCI論文65篇。

代表性論著

• Zheng P, Wang Y, Chen L, Yang DY, Meng HQ, Zhou DZ, Zhong JJ, Lei Y, Melgiri ND,Xie P. Identification and validation of urinary metabolite biomarkers for major depressive disorder. Mol Cell Protomics, 2013; 12(1):207-14

• Zheng P , Chen JJ , Huang T, Wang MJ, Wang Y, Dong MX , Huang YJ , Zhou LK ,Xie P. A Novel urinary metabolite signature for diagnosing major depressive disorder.J Proteome res, 2013,12(12):5904–5911

• Zheng P, Wei YD, Yao GE, Ren GP, Guo J, Zhou CJ, Zhong JJ, Cao D, Zhou LK,Xie P. Novel urinary biomarkers for diagnosing bipolar disorder.Metabolomics, 2013; 9(4) :800-808

• Shao WH, Fan SH, Lei Y, Yao GE, Chen JJ, Zhou J, Xu HB, Liu HP, Wu B, Zheng P,Xie P. Metabolomic identification of molecular changes associated with stress resilience in the chronic mild stress rat model of depression. Metabolomics, 2013; 9(2):433-443

• Lei Y, Li D, Deng J, Shao WH, Fan SH, Wang X,Hua Huang, Chen SG, Zhang HZ, Zhang L, Zhang Y, Li WJ, Huang RZ, Liu X, Zhou CJ, Chen JJ,Xie P. Metabolomic profiling of three brain regions from a postnatal.infected Borna disease virus Hu-H1 rat model.Metabolomics, DOI: 10.1007/s11306-013-0593-y

• Li X, Xu F, Xie L Ji YJ, Cheng K, Zhou QM, Wang T, C.Shively, Wu QY, Gong W, Fang L, Zhan QL, N. D. Melgiri,Xie P. Depression-Like Behavioral Phenotypes in the Socially and Socio-Visually Isolated Adult Female Macaca Fascicularis.PLOS ONE,2013,8(9): e73293

• Liu XL , Zhang L , Cheng K, Wang X, Ren GP ,Xie P. Identification of suitable plasma-based reference genes for miRNAome analysis of major depressive disorder.J Affect Disorders

• Zhang L , Xu MM , Zeng L , Liu S , Liu X , Wang X , Li D , Huang RZ , Zhao LB , Zhang QL , Zhu D , Zhang YY , Xu P ,Xie P. Evidence for Borna disease virus infection in neuropsychiatric patients in three western China provinces.Eur J Clin Microbiol Infect Dis, 2013. DOI: 10.1007/s10096-013-1996-4

• Deng M, Wei L, Zuo X, Tian Y, Xie F, Hu P, Zhu C, Yu F, Meng Y, Wang H, Zhang F, Ma H, Ye R, Cheng H, Du J, Dong W, Zhou S, Wang C, Wang Y, Wang J, Chen X, Sun Z, Zhou N, Jiang Y, Liu X, Li X, Zhang N, Liu N, Guan Y, Han Y, Han Y, Lv X, Fu Y, Yu H, Xi C, Xie D, Zhao Q,Xie P, Wang X, Zhang Z, Shen L, Cui Y, Yin X, Cheng H, Liang B, Zheng X, Lee TM, Chen G, Zhou F, Veldink JH, Robberecht W, Landers JE, Andersen PM, Al-Chalabi A, Shaw C, Liu C, Tang B, Xiao S, Robertson J, Zhang F, van den Berg LH, Sun L, Liu J, Yang S, Ju X, Wang K, Zhang X. Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nature Genetics, 2013;45,697-700

• Huang RZ, Gao HC, Ma LH, Jia JM, Wang X, Wang MJ, Zhang L, Liu X, Zhnen p, Yang L, Lei y, Li D,Xie P. Dynamic 1H NMR-based extracellular metabonomic analysis of oligodendroglia cells infected with herpes simplex virus type 1. Metabolomics, 2013; 10.1007/s11306-013-0548-3

• Wang T, Huang XL, Huang PY, Li D, Lv FJ, Zhang Y, Yang DY,Xie P. Early-stage psychotherapy produces elevated frontal whit matter integrity in adult major depressive disorder. Plos ONE, 2013;8(4):e63081

• Chen JJ , Zhou CJ , Wu B , Wang Y , Li Q , Wei YD , Yang DY , Mu J , Zhu D , Zou DZ ,Xie P.Left versus Right Repetitive Transcranial Magnetic Stimulation in Treating Major Depression: a Meta-Analysis of Randomized Controlled Trials.Psychiatry Research,2013,210(3): 1260–1264

• Liu HP , Zhou J , Fang L , Liu Z , Fan SH ,Xie P.Acute tryptophan depletion reduces nitric oxide synthase in the rat hippocampus.Neurochemical Research,2013,38(12):2595-2603

• Li Q ,Xie P. Outpatient workload in China. The Lancet, 2013; 381(9882):1983 – 1984.

• Xie L, XU F, Liu SG, Ji YJ, Zhou QM, Wu QY, Gong W, Cheng K, Li J, Li LL, Fang L, Zhou LK,Xie P.Age- and sex-based hematological and biochemical parameters for macaca fascicularis. Plos ONE, 2013 ;8(6): e64892

• Li D, Lei Y, Deng J, Zhou CJ, Zhang Y, Li WJ, Huang H, Cheng SG, Zhang HZ,Zhang L,Huang RZ, Liu X, Ma LH, Wang X, Li J,Xie P. Human but not laboratory Borna disease virus inhibits proliferation and induces apoptosis in human oligodendrocyte in vitro. Plos ONE, 2013, 8(6): e66623

• Huang W, Zhao P, Chen X, Li P, Zhao GN, Xu MM, Chen XY,Xie P. Comparative study of different latent infections of herpes simplex virus type i in a murine model. Cell Biochem Biophys, 2013; DOI:10.1007/s12013-013-9682-9

• Yang YT, Yang DY, Tang G, Zhou CJ, Cheng K, Wu B, Peng Y, Liu CY, Zhan Y, Chen JJ, Chen GH,Xie P. Proteomics reveals energy and glutathione metabolic dysregulation in the prefrontal cortex of a rat model of depression. Neuroscience, 2013; 247, 191–200

• Zeng L, Guo J, Xu HB, Huang RZ, Shao WH, Yang L, Wang MJ, Chen JJ,Xie P. Direct blue 71 staining as a destaining-free alternative loading control method for western blotting. Electrophoresis, 2013; DOI:10.1002/elps.201300140

• Li Q, Lv FJ, Wei YD, Luo TY,Xie P. Automated subtraction ct angiography for visualization of the whole brain vasculature: a feasibility study. Acad Radiol, 2013; 20 (8): 1009-1014

• Hu YB, Zhou J, Fang L, Liu HP, Zhan QL, Luo D, Zhou CJ, Chen JJ, Li Q,Xie P. Hippocampal synaptic dysregulation of exo/endocytosis-associated proteins induced in a chronic mild stressed rat model. Neuroscience, 2013; 230:1-12

• Huang W, Zhao Y, Zhu X, Cai Z, Wang S, Yao S, Qi Z,Xie P. Fluoxetine upregulates phosphorylated-AKT and phosphorylated-ERK1/2 proteins in neural stem cells:evidence for a crosstalk between AKT and ERK1/2 pathways. J Mol Neurosci, 2013; 49(2):244-9

• Ji YJ, Xie L, Liu S, Cheng K, Xu F, Li X, Wang T, Zhou QM, Fang L,Xie P. Correlation of thoracic radiograph measurements with age in adolescent chinese rhesus macaques (macaca mulatta). J Am Assoc Lab Anim,2013; 52(1):78-82

• Huang PY, Qiu LH, Shen L, Zhang Y, Song Z, Qi ZG, Gong QY,Xie P. Evidence for a left-over-right inhibitory mechanism during figural creative thinking in normal non-artists.Hum Brain Mapp, 2012; DOI:10.1002/hbm.22093

• Zhou XY, Chen JJ, Li Q, Ren GP, Yao GE, Liu M, Dong Q, Guo J, Li L, Guo J,Xie P. Minimally invasive surgery for spontaneous supratentorial intracerebral hemorrhage: a meta-analysis of randomized controlled trials. Stroke, 2012; 43(11):2923-30

• Zheng P, Gao HC, Li Q, Shao WH, Zhang ML, Cheng K, Yang de Y, Fan SH, Chen L, Fang L,Xie P. Plasma metabolomics as a novel diagnostic method for major depressive disorder. J Proteome Res, 2012; 11 (3):1741-1748

• Xu HB, Zhang RF, Luo D, Zhou Y, Wang Y, Fang L, Li WJ, Mu J, Zhang L, Zhang Y,Xie P. Comparative proteomic analysis of plasma from major depressive patients: identification of proteins associated with lipid metabolism and immunoregulation. International Journal of Neuropsychoph, 2012; 15(10):1413-25

• Zheng P, Gao HC, Qi ZG, Jia JM, Li FF, Chen JJ, Wang Y, Guo J, N. D. Melgiri,Xie P. Peripheral metabolic abnormalities of lipids and amino acids implicated in increased risk of suicidal behavior in major depressive disorder. Metabolomics. 2012; 9(3): 688-696

• Xu F, Xie L, Li X, Li Q, Wang T, Ji YJ, Kong F, Zhan QL, Cheng K, Fang L,Xie P. Construction and validation of a systemtic ethogram of macaca fascicularis in a free enclosure. Plos One, 2012;7(5):e37486

• Huang RZ, Gao HC, Zhang L, Jia JM, Liu X, Zheng P, Ma LH, Li WJ, Deng J, Wang X, Yang L, Wang MG,Xie P. Borna disease virus infection perturbs key metabolites associated with neuropsychiatric disorders in cultured human oligodendroglioma Cells. Plos One, 2012;7(9):e44665

• Huang W, Chen X, Li Q, Li P, Zhao G, Xu M,Xie P. Inhibition of intercellular adhesion in herpex simplex virus infection by glycyrrhizin. Cell biochem biophys, 2012; 62:137-40

• Zhang RF, Yang DY, Zhou CJ, Cheng K, Liu Z, Chen L, Fang L,Xie P. β-actin as a candidate loading control in western blot analysis of plasma from depressed patients. Anal Biochem, 2012;427:116-120

• Xu HB, Fang L, Hu ZC, Chen YC, Chen JJ, Li FF, Lu J, Mu J,Xie P. Potential clinical utility of plasma aminoacid profiling in the detection of major depressive disorder. Psychiat Res, 2012; 200(2-3):1054-7

• Li D, Deng J, He H, Bu Y, Peng F, Tang X, Wang B, Lei Y, Zhang H,Xie P. Primary breast diffuse large B-cell lymphoma shows an activated B-cell–like phenotype. Ann Diagn Pathol, 2012; 16(5):335-43

• Huang W,Xie P,Xu M, Li P, Zao G. The influence of stress factors on the reactivation of latent herpes simplex virus type 1 in infected mice. Cell Biochem Biophys, 2011;61(1): 115-122

• Zhou J, Hua YB, Lin Y, Liu HP,Xie P. Preparation and application of a partially degradable gel in mass spectrometry-based proteomic analysis. J Chromatogr B, 2011; 879(28):2957-2962

• Yang DY, Li Q, Fang L, Cheng K, Zhang RF, Zheng P, Zhan QL, Qi ZG, Zhong S,Xie P. Reduced neurogenesis and pre-synaptic dysfunction in the olfactory bulb of a rat model of depression. Neuroscience, 2011;192: 609-618

• Yang DY, Liu X, Zhang RF, Cheng K, Mu J, Fang L,Xie P. Increased apoptosis and different regulation of pro-apoptosis protein bax and anti-apoptosis protein bcl-2 in the olfactory bulb of a rat model of depression.Neurosci Lett, 2011; 504(1): 18-22

• Li Q, Li J, Lv F, Li K, Luo T,Xie P. A multidetector CT angiography study of variations in the circle of Willis in a Chinese population. J Clin Neurosci, 2011; 18(3): 379-83

• Zhang L,XieP, Wang J, Yang Q, Fang C, Zhou S, Li J. Impaired peroxisome proliferator-activated receptor-γ contributes to phenotypic modulation of vascular smooth muscle cells during hypertension. J Biol Chem, 2010; 285(18):13666-77

• Li D,Xie P, Mi C. Primary testicular diffuse large B-cell lymphoma shows an activated B-cell-like phenotype. Pathol Res and Pract, 2010;206(9): 611-615

• Lin X, Li D,XieP, Mi C, Lin Q. Primary testicular NK/T-Cell lymphoma: A study of two cases and review of literature. Chinese J Cancer Res, 2010; 22(3):239-244

• Tang J, Li YJ, Li Q, Mu J, Yang DY, Xie P. Endogenous tissue plasminogen activator increases hemorrhagic transformation induced by heparin after ischemia reperfusion in rat brains. Neurol Res, 2010;32(5):541-6

• Li Q, Lv F, Li Y, Luo T, Li K,Xie P. Evaluation of 64-section CT angiography for detection and treatment planning of intracranial aneurysms by using DSA and surgical findings. Radiology, 2009; 252(3): 808-15

• Li Q, Lv F, Li Y, Li K, Luo T,Xie P. Subtraction CT angiography for evaluation of intracranial aneurysms: Comparison with conventional CT angiography. Eur Radiol, 2009; 19(9): 2261-7

• Li Q, Wang Z, Zhu D, Xu M, Chen X, Peng D, Iwata Y,Xie P. Detection and analysis of borna disease virus in Chinese patients with neurological disorders. Eur J Neurol, 2009; 16(3): 399-403

• Shen L, Zeng ZL, Huang PY, Li Q, Mu J, Huang XQ, Lui S, Gong QY,Xie P. Temporal cortex participates in spontaneous perceptual reversal. Neuroreport, 2009; 20(7): 647-51

• Zhu D, Kang Q, Huang PY, He TC,Xie P. Neurogenesis-related genes expression profiling of mouse fibroblastic stem cells induced by Wnt signaling.Neurol Res, 2009; 31(2): 200-3

• Tang J, Li YJ, Mu J, Li Q, Yang DY,Xie P. Albumin ameliorates tissue plasminogen activator-mediated blood-brain barrier permeability and ischemic brain injury in rats. Neurol Res, 2009;31(2):189-94

• Li Y,Xie P, Fan X, Tang H. Balo's concentric sclerosis presenting with benign clinical course and multiple sclerosis-like lesions on magnetic resonance images. Neurol India, 2009;57(1):66-8

• Wang T, Zhang QL, Li H, Qiu J, Tu S,Yu CY. The time course of chinese riddles solving: Evidence from an ERP Study. Behavl Brain Res, 2009;199(2): 278-82

• Li YM, lv FJ, Mu J, li Q, Yang Q, Hu M, Tang H, Yi J,Xie P. Brain magnetic resonance imaging abnormalities in neuromyelitis optica. Acta Neurol Scand, 2008;118(4):218-225

• Mu J, Yang ZS,Xie P. Proteomic analysis of a rat model of depression. Expert Rev Proteomic,2008; 5(2): 315-320

• Yang Q, Mu J, Li Q, Li A, Zeng Z, Yang J, Zhang X, Tang J,Xie P. A simple and efficient method for deriving neurospheres from bone marrow stromal cells. Biochem Biophy Res Co, 2008; 372(4):520-4

• Fu Y,Xie P, Meng H, Qin Q, Jia L, Li Q, Huang Y, Hou X, Luo Q, Ma X, Deng W, Wang Y, Hu H, Du L, Feng K, Qiu H, Xiang Y, Li T. The construction and prospects of the Chongqing twin children database. Twin Res Hum Genet, 2008; 11(6): 629-33

• Li Q,Xie P, Qin X. Susac's syndrome presenting with consciousness disturbance. Eur J Intern Med, 2008;19(3):223

• Mu J, Yang ZS, Yang DL, Lv FJ, Luo TY, Li Y,Xie P. H magnetic resonance spectroscopy study of thalamus in treatment resistant depressive patients. Neurosci Lett, 2007;425(1):49-52

• Mu J, Yang ZS, Yang DL, Lv FJ, Luo TY, Li Y,Xie P. Neurogenesis and major depression: Implications from proteomic analyses of hippocampal proteins in a rat depression model.Neurosci Lett, 2007;416(3):252-256

• Iwata Y,Takahashi K,Xie P,Fukuda K,Ohno K,Ogawa T,Gonda K,Mori N,Niwa S,Shigeta S.Detection and sequence analysis of Borna disease virus p24RNA from peripheral blood mononuclear cells of patients with mood diorders and schizophrenia.Journal of Virology. 1998; 72 (12) : 10044.-10049

國務院學位委員會第六屆學科評議組成員。

教育部第二屆全國專業學位教育指導委員會委員。

中華醫學會神經病學分會副主任委員。

中國醫師協會神經內科醫師分會會長。

擔任《Stroke,BrainResearch》雜誌的特約審稿人。

擔任全國醫學院校五年制統編教材《神經病學》第四、五、六、七版編委，《臨床神經化學》雜誌主編，《中國神經科雜誌》《中國神經精神疾病雜誌》《中華神經醫學雜誌》《中國實用內科雜誌》《中國腦血管疾病雜誌》《國際腦血管病雜誌》《國際神經病學神經外科學雜誌》等10家雜誌編委。

擔任全國研究生統編教材《神經內科學》主編。

2010年，“美中友好志願者項目”評估座談會在重慶醫科大學行政樓二樓會議室舉行。重慶醫科大學副校長謝鵬教授，外事處楊紅處長，原外語系主任胡燕平教授等參會。