共找到3條詞條名為李夢龍的結果 展開

李夢龍

四川大學化學學院副院長

李夢龍,1962 年生,理學博士,教授、博士生導師。

人物經歷


1962 年生,理學博士,教授、博士生導師。
1978-1990 年於湖南大學分析化學專業獲理學學士、碩士、博士學位。
1990 年進入四川大學化學學院任教。
現為四川大學教授,博士生指導教師,九三學社社員,教育部高校理科化學教學指導委員會委員、中國化學會化學教育學科委員會委員、中國化學會計算機化學專委會委員、中國儀器儀錶學會分析儀器學會理事、四川省化學化工學會分析化學專委會副主任,《應用基礎與工程科學學報》編委、《環境化學》編委。四川大學教學名師,四川省精品課程《分析化學》負責人。
國家教育部高等學校理科化學教學指導委員會委員,中國化學會化學教育委員會、計算機化學專業委員會委員,四川大學化學學院副院長,教育部骨幹教師、優秀年輕教師基金獲得者。

研究方向


研究領域:
化學信息學:以計算機輔助光譜結構性能關係為基礎,結合化學計量學模型與演演算法的研究,構建新穎實用的基於小波變換光譜-結構關聯體系;化學軟體研發。
生物信息學:蛋白質資料庫序列的分類和歸屬研究;蛋白質結構解析演演算法;蛋白質及相關類資料庫管理系統的研發。

主要貢獻


發表學術論文近 90 篇,著作 4 部,獲部省級教學與科研成果獎5項。

工作業績

主持主研完成(含在研)了國家自然科學基金項目5項,教育部優秀年輕教師基金、博士學科點專項基金和骨幹教師基金各1項,其他省部級科研課題多項,獲部省級成果2項,發表論文90餘篇,出版專著2部,現為四川省化學化工學會分析化學專業委員會副主任、中國化學會化學教育委員會委員、四川省學術帶頭人(後備人選)、省跨世紀傑出青年學科帶頭人。國家教育部高校理科化學教學指導委員會無機及分析化學指導組成員。

代表論著

蛋白質信息學:
1. Yanzhi Guo, Menglong Li*, Minchun Lu, Zhining Wen, Zhongtian Huang, Predicting G-protein coupled receptors-G-protein coupling specificity based on autocross-covariance transform. Proteins: structure, function, and bioinformatics, 2006, 65, 55-60。
2. Yanzhi Guo, Menglong Li*, Minchun Lu, Zhining Wen, Kelong Wang, Gongbin Li, Jiang Wu. Classifying G protein-coupled receptors and nuclear receptors on the basis of protein power spectrum from fast Fourier transform. Amino Acids. 2006, 30, 397-402。
3. Yanzhi Guo, Menglong Li*, Kelong Wang, Zhining Wen, Minchun Lu, Lixia Liu, Lin Jiang, Fast Fourier Transform-based Support Vector Machine for Prediction of G-protein Coupled Receptor Subfamilies. Acta Biochimica et Biophysica Sinica, 2005, 37, 759–766。
4. Zhining Wen, Menglong Li*, Yizhou Li, Yanzhi Guo, Kelong Wang, Delaunay triangulation with partial least squares projection to latent structures: a model for G-protein coupled receptors classification and fast structure recognition. Amino Acids. 2006, DOI: 10.1007/ s-y。
5. Kelong Wang, Zhining Wen, Fusheng Nie, Menglong Li*, A new hybrid model of amino acid substitution for protein. Chinese Chemical Letters, 2005, 16, 1133-1136。
6. Zhining Wen, Kelong Wang, Menglong Li*, Fusheng Nie, Yi Yang, Analyzing functional similarity of protein sequences with discrete wavelet transform. Computational biology and Chemistry. 2005, 29, 220-228。
7. Lin Jiang, Menglong Li*, Zhining Wen, Kelong Wang, Yuanbo Diao, Prediction of mitochondrial proteins using discrete wavelet transform. The protein Journal. 2006, 25(4):241-299。
8. Lixia Liu, Menglong Li*, Fuyuan Tan, Minchun Lu, Kelong Wang, Zhining Wen, Yanzhi Guo, Lin Jiang, Local sequence information based Support Vector Machine to classify voltage-gated potassium channels. Acta Biochimica et Biophysica Sinica, 2006, 38, 363-371。
9. Fuyuan Tan, Xiaoyu Feng, Zheng Fang, Menglong Li*, Yanzhi Guo, Lin Jiang, Prediction of mitochondrial proteins based on genetic algorithm – partial least squares and support vector machine, Amino Acids. 2006, DOI 10.1007/ s--0。
10. Wenli Qin, Yizhou Li, Juan Li, Lezheng Yu, Di Wu, Runyu Jing, Xuemei Pu, Yanzhi Guo*, Menglong Li*, Predicting deleterious non-synonymous single nucleotidepolymorphisms in signal peptides based on hybrid sequence attributes. Comput.Bio. Chem. 2012, 36, 31-35。
11. JiesiLuo, Lezheng Yu, Yanzhi Guo *,Menglong Li*, Functional classification of secreted proteins by positionspecific scoring matrix and auto covariance. Chemom. Intell. Lab. Syst.,2012,110, 163-167。
12. Yanzhi Guo, Xuemei Pu, MenglongLi*, Gongbin Li, Xuanmin Guang, Wenjia Xiong, Juan Li, Short Report PRED_PPI:aserver for predicting protein-protein interactions based on sequence data withprobability assignment, BMC. Research. Notes,2010 ,3,145。
13. Lijuan Zhu,Wei Yang, YanYan Meng, Yanzhi Guo, Xuemei Pu, Menglong Li*, Effects of organic solvent and the crystalwater on g-chymotrypsin in acetonitrile media:observations from molecular dynamics simulation and DFT calculation, J.Phys .Chem. B,dx.doi.org/10.1021/jp3002405。
14. Xiuchan Xiao, Ying Tan, Lijuan Zhu, Yanzhi Guo, Zhining Wen,Menglong Li*, Xuemei Pu, Anmin Tian, Effects of the position and manner ofhydration on the stability of solvated N-methylacetamides and the strength ofbinding between N-methylacetamide and water clusters: a computational study, J.Mol. Model, DOI 10.1007/s00894-011-1166-5。
15. Anqun Chen , Xuemei Pu, Shuhua He,Yanzhi Guo, Menglong Li*, Ning-Bew Wong, AnminTian, Solvent Effects on Isolated Formamide and ItsMonohydrated Complex: Observations from PCM Study, New J. Chem.,2009, 33,1709-1719。
16. Yizhou Li, Gingbin Li,Zhining Wen, Jiamin Xiao, Hui Yin, Mei Hu, Menglong Li*, Novel feature for catalytic protein residuesreflecting interactions with other residues. PLoS ONE.,doi:10.1371/journal.pone.0016932。
17. Yizhou Li, Wen Zhining, Jiamin Xiao, Hui Yin,LeZheng Yu, Li Yang, Menglong Li*, Predicting disease-associated substitution ofa single amino acid by revealing residue interactions. BMCBioinformatics, 2011, 12:14, doi:10.1186/1471-2105-12-14。
18. Ying Tan, Lijuan Zhu, Xiuchan Xiao, Yanzhi Guo,Menglong Li*, Anmin Tian,Xuemei Pu, A Comparative study of Meta/Para Substitution effects on theHydrogen-Bonded Complex of Aniline-H2O:Observations from Computation, J. Theor. Comput. Chem.,2011, 10,567-579。
19. Shuhua He, Ying Tan, Xiuchan Xiao, Lijuan Zhu, Yanzhi Guo,Menglong Li*, Anmin Tian, Xuemei Pu,*, Ning-Bew Wong, Substituent effects on electroniccharacter of the C=N group and trans/cis isomerization in the C-substitutedimine derivatives:A computational study, J. Mol. Struct.Theochem,2010, 951, 7-13。
20. Daichuan Ma, Yuanbo Diao, Yanzhi Guo, Yizhou Li, Yongqing Zhang, Jiang Wu, MenglongLi*, A Novel Method to PredictProtein-Protein Interactions Based on the Information of Protein-ProteinInteraction Networks and Protein Sequence. Protein Peptide Lett, 2011, 18,906-911。
21. Daichuan Ma, Jiamin Xiao, Yizhou Li, Yuanbo Diao, Yanzhi Guo, Menglong Li*, Feature importance analysis in guide strandidentification of microRNAs. Comput. Boil. Chem., 2011, 35,131–136。
22. Lezheng Yu, YanzhiGuo, Zheng Zhang, Yizhou Li, Menglong Li*, Gongbing Li, Wenjia Xiong, YuhongZeng, SecretP: A new method for predicting mammalian secreted proteins. Peptides,2010, 31, 574–578。
23. Lezheng Yu, YanzhiGuo, Yizhou Li, Gongbing Li, Menglong Li*, SecretP: Identifyingbacterial secreted proteins by fusing new features into Chou’s pseudo-aminoacid composition. J. Theor. Biol., 2010,267, 1-6。
24. Xuanmin Guang, YanzhiGuo, Jaimin Xiao, Xia Wang, Jing Sun, Wenjia Xiong, Menglong Li*,Predicting the state of cysteines based on sequence information. J. Theor.Biol., 2010,267, 312-318。
25. Xuanmin Guang, YanzhiGuo, Xia Wang, Menglong Li*, Prediction of Neurotoxins by Support Vector Machine basedon Multiple Feature Vectors. Interdiscip Sci Comput Life Sci, 2010, 2, 241-246。
26. Wenjia Xiong, Yanzhi Guo,Menglong Li*, Prediction of Lipid-Binding Sites Based on Support Vector Machineand Position Specific Scoring Matrix. Protein. J., 2010, 29, 427-431。
27. YuhongZeng, Yanzhi Guo, RongquanXiao, Li Yang, Lezheng Yu, Menglong Li*, Prediction of Mitochondrial proteinsbased on genetic algorithm-partial least squares and support vector machine. J. THEOR. BIOL., 2009,259, 366-372。
28. Rongquan Xiao, Yanzhi Guo, Yuhong Zeng, HaifengTan, Xuemei Pu, Menglong Li*, Using position specific scoring matrix and autocovariance to predict protein subnuclear localization. J. Biomed.Sci. Eng., 2009, 2, 51-56。
29. Jiamin Xiao, YizhouLi, Kelong Wang, Zhining Wen, Menglong Li*, In silico method forsystematic analysis of feature importance in microRNA-mRNA interactions. BMC Bioinformatics, 2009, 10, 427,doi: 10.1186/1471-2105-10-427。
30. Jiajian Yin,Yuanbo Diao, Zhining Wen, Zhimeng Wang, Menglong Li*, Studyingpeptides biological activities based on multidimensional descriptors (E) usingsupport vector regression. Int. J.Pept. Res. Ther. 2010, 16:111-121。
31. Yi Li, ZhiNingWen, LongJiang, MengLong Li*, Ning Gao ,YanZhi Guo,Research on the Raman spectral character and diagnostic value of squamous cellcarcinoma of oral mucosa. J. Ramnan. Spectrosc.2009, Doi: 10.1002/jrs.2421。
32. Fuyuan Tan,Xiaoyu Feng, Zheng Fang, Menglong Li*, Yanzhi Guo, Lin Jiang,Prediction of mitochondrial proteins based on genetic algorithm – partial leastsquares and support vector machine, AminoAcids. 2007,33,669-675。
33.Zhimeng Wang,Lin Jiang, Menglong Li*, LinaSun, Rongying Lin, FastFourier Transform-based Support Vector Machine for Subcellular LocalizationPrediction using Different Substitution Models. Acta Bioch Bioph Sin. 2007, 39, 715-721。
計算機輔助波譜解析:
34. Chao Tan, Menglong Li*, Calibration Transfer between Two Near-Infrared Spectrometers Based on Wavelet Packet Transform,Analytical Sciences,2006(Accepted)。
35. Meng-long Li*, Fu-sheng, Nie, Hua-yi, Qi, Zhi-ning, Wen, Bin, Kang, Method for infrared spectral compression based on the embedded zerotree wavelet. Spectroscopy Letters, 2005, 38, 171-184.。
36. Wei XIE, Fu Sheng NIE, Meng Long LI *, Guang Ming LI, Min Chun LU. Alcohols' Classification by their Infrared Spectra Segment Based on Support Vector Machines, Chinese Chemical Letters, 2006, 17, 929-932。
37. Junhong Liu, Minchun Lu, Fusheng Nie, Xiaoyu Feng, Menglong Li*, Functional Group Prediction from Infrared Spectra by using Support Vector Machines, Chinese Chemical Letters,, 2005,16(10):1354-1356。
38. 謝微,李光明, 陸敏春, 聶伏生, 李夢龍*. 基於支持向量機的羰基化合物紅外光譜研究,分析化學,2006,34:s113-s117。
合作研究(生命分析方向):
39. Cuisong Zhou, Yaxin Jiang, Baocheng Ma, Menglong Li*, Xiaohong Fang*, Detection of Oncoprotein Platelet-Derived Growth Factor Using Fluorescent Signaling Complex of Aptamer and TOTO,Analytical & Bioanalytical Chemistry, 2006, 384, 1175-1180。
40. 周翠松, 江雅新,汪俊, 麻寶成, 李夢龍*,方曉紅*,信號核酸識體用於藥物托普黴素的高靈敏度檢測,高等學校化學學報, 2006,27(5)826-829。

教研論文

1、 VRML-虛擬現實建模語言在化學教育中的應用,計算機與應用化學,2002, 19(4)。
2、化學網路資料庫在WEB中的實現,化學通報,2003,66(12):W125。
3、部分化學資源資料庫的構建,四川大學學報,2003,40(2):662-666。
4、信息化學研究進展,化學研究與應用,2002,14(1)90-95。
5、小型化學實驗室信息管理系統的設計與開發,化學研究與應用,2004。
6、 The application of chemical element reaction database based on Web in the teaching innovation,IUPAC國際化學教育會議(2005,北京)。
7、 The Design of Fingerprints Quality Evaluation Teaching System,IUPAC國際化學教育會議(2005,北京)。
8、 REPC:Remote Education Platform for Chemistry,IUPAC國際化學教育會議(2005,北京)。
9、 The Designing of chemical Experimental Instruction and Management System based on Web,IUPAC國際化學教育會議(2005,北京)。
10、網路教育在大學化學教學改革中的影響,寧夏大學學報(自然科學版),2007,28:348-349 。
11、創新人才培養中科研對本科教學的促進作用探討,廣西師範大學學報(自然科學版),2007,25:47-48 。
12、大學化學實驗教學模式的改革——淺談計算機輔助教學系統的建設和作用,廣西師範大學學報(自然科學版),2007,25:172-174。
13、以“科研教學互動”為核心,開展本科教學改革 ?淺談課題組的科研成果在分析化學教學中的實踐應用和體會,第十三屆全國普通高等院校分析化學教學研討會,2008,揚州。
14、化學信息學課程建設管窺,第十三屆全國普通高等院校分析化學教學研討會,2008,揚州。

教材教輔

1.李夢龍,《Internet與化學信息導論》,化學工業出版社,2001。
2.李夢龍,《化學數據速查手冊》,化學工業出版社,2003。
3.李夢龍,等,《化學軟體及其應用》,化學工業出版社,2004。