潘建平

主要研究方向：腫瘤免疫學，黏膜抗感染免疫的細胞和分子機制

在研科主要研項目：不同亞群PP-DC在B細胞向腸黏膜歸巢和IgA產生中的作用及其機制（國家自然科學基金，30872325）

發表的主要論文：

⒈ Lu J,Zheng MH,Yan J,Chen YP,Pan J. Effects of vasoactive intestinal peptide on phenotypic and functional maturation of dendritic cells. Inter Immunopharmacol 2008; 8:1449-1454.

⒉ Pan J,Jin P,Yan J,Kabelitz D. Anti-angiogenic active immunotherapy: a new approach to cancer treatment. Cancer Immunol Immunother 2008; 57:1105-1114.

⒊ Weng Y,Sun J,Wu Q,Pan J. Regulatory effects of vasoactive intestinal peptide on the migration of mature dendritic cells. J Neuroimmunol 2007; 182: 48-54.

⒋ Shao P,Zhao LH,Chen Z,Pan J. Regulation on maturation and function of dendritic cells by Astragalus mongholicus polysaccharides. Inter Immunopharmacol 2006; 6: 1161-1166.

⒌ Pan J,Heiser A,Maret M,Steinmann J,Kabelitz D. Enhanced anti-metastatic effect of fetal liver kinase 1 and interferon-gamma fusion gene-modified dendritic cell vaccination. Gene Ther 2005; 12:742-750.

⒍ Pan J,Zhang M,Wang J,Wang Q,Xia D,Sun W,Zhang L,Yu H,Cao X. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8+ CTL response. J Cancer Res Clin Oncol 2005; 131:468-478.

⒎ Pan J,Zhang M,Wang J,Wang Q,Xia D,Sun W,Zhang L,Yu H,Liu Y,Cao X. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett. 2004; 94 : 141-151.

⒏ Pan J,Ju DW,Wang Q,Zhang M,Xia D,Zhang L,Yu H,Cao X. Dexamethosone inhibits the antigen presentation of dendritic cells in MHC class Ⅱ pathway. Immunol Lett 2001; 76 ⑶： 153-161.

⒐ Zhang LH，Pan JP，Yao HP,et al. Intrasplenic transplantation of IL-18 gene-modified hepatocytes: an effective approach to reverse hepatic fibrosis in schistosomiasis through induction of dominant Th1 response. Gene Ther 2001; 8: 1333-1342.

⒑ Sun W,Wang Q,Zhang L,Pan J,Zhang M,Lu G,Yao H,Wang J,Cao X. TGF-beta ⑴ gene modified immature dendritic cells exhibit enhanced tolerogenicity but induce allograft fibrosis in vivo. J Mol Med. 2002; 80 ⑻： 514-23.

⒒ Xia DJ,Zhang WP,Zheng S,Wang J,Pan JP,Wang Q,Zhang LH,Hamada H,Cao X. Lymphotactin cotransfection enhances the therapeutic efficacy of dendritic cells genetically modified with melanoma antigen gp100. Gene Ther 2002; 9 ⑼： 592-601.

⒓ Xia D,Zheng S,Zhang W,He L,Wang Q,Pan J,Zhang L,Wang J,Cao X. Effective induction of therapeutic antitumor immunity by dendritic cells coexpressing interleukin-18 and tumor antigen. J Mol Med. 2003; 81 ⑼： 585-96.

⒔ Wang Q,Yu H,Ju DW,He L,Pan JP,Xia D,Zhang L,Cao X. Intratumoral IL-18 gene transfer improves therapeutic efficacy of antibody-targeted superantigen in established murine melanoma. Gene Ther 2001; 8 ⑺： 542-550.

⒕ Wang Q,Yu H,Zhang LH,Ju DW,Pan JP,Xia DJ,He L,Wang J,Cao X. Vaccination with IL-18 gene-modified,superantigen-coated tumor cells elicits potent antitumor immune response. J Cancer Res Clin Oncol 2001; 127 ⑿： 718-726.

⒖ Wang Q,Yu H,Zhang LH,Ju DW,Pan JP,Xia DJ,He L,Wang J,Cao X. Adenovirus-mediated intratumoral lymphotactin gene transfer potentiates the antibody-targeted superantigen therapy of cancer. J Mol Med 2002; 80 ⑼： 585-594.

⒈張立煌、姚航平、冷建杭、李敏偉、陳紅、潘建平、孫文佶。細胞因子基因修飾肝細胞經脾移植治療肝纖維化和肝癌的實驗研究。浙江省科學技術獎三等獎。2003年12月。

⒉嚴傑、毛亞菲、孫愛華、羅冬嬌、潘建平、陳學軍等。內置LTB幽門螺桿菌UreB-HpaA兩價口服基因工程疫苗的實驗研究。浙江省科學技術獎二等獎。2007年09月。

主編和參編的著作和教材：

⒈潘建平，邵傳森主編。《醫學免疫學》浙江大學出版社，2006年8月第一版。

⒉潘建平。第八章 抗原和抗原提呈，第九章 免疫應答，第十章 免疫耐受，第十一章 免疫調節。張麗芳，張立煌主編。《醫學免疫學與微生物學》。北京：人民衛生出版社，2007年2月第一版。65-104.

⒊祝文嫻，潘建平。肺的免疫功能。周漢良，陳季強主編。呼吸藥理學與治療學。第一版。北京：人民衛生出版社，1999年。175-206