胡海洋

1996年08月至2000年07月：瀋陽藥科大學藥劑專業學習 獲工學學士學位

2000年08月至2005年12月：瀋陽藥科大學藥劑專業學習 獲理學博士學位

2006年03月至今：瀋陽藥科大學藥學院藥劑教研室 講師

科研/獲獎情況：

主要研究方向：靶向藥物傳釋系統及其載體材料研究。主持國家自然科學基金、遼寧省教育廳項目各一項。參與國家“十一五”科技支撐項目（2006BAI091308-04）、國家重大專項項目“大濃度複合維生素注射液的研究”、國家自然基金項目（30873181），新藥品種開發課題共多項。在國內外學術期刊已發表學術論文約35篇；申報國家發明專利2項。2006、2007年獲遼寧省自然科學學術成果三等獎，2008年獲中國藥學會年會論文二等獎，2010年獲中國中藥學會年會論文一等獎。

教學/指導研究生情況：

主要參與本科《藥劑學》及《藥劑學實驗》的教學

發表論文/出版著作：

1. Dan L., H. Hu, Jie Z, X. Zhao, X. Tang, Chen D., Drug pH-sensitive release in vitro and Target ability of PAMAM dendrimers complexes on Tumor cells, CPB., 2010,

2. H. Hu, D. Chen, Y. Liu, Y. Deng, S. Yang, M. Qiao, J. Zhao, X. Zhao, Target ability and therapy efficacy of Immunoliposomes using a humanized anti-hepatoma disulfide-stabilized Fv fragment on tumor cells, J. Pharm. Sci., 2006, 95(1):192-199.

3. H. Hu, D. Chen, Y. Li, X. Zhang, Effect of growth inhibition and apoptosis induction of polypepetides in bee venom on human hepatoma cell line SMMC-7721 in vitro and Balb/c nude mice in vivo, J. Pharm. Pharmaco, 2006, 58(1): 83-89.

徠4.Wang W, Zhao X, Hu H, Chen D, Gu J, Deng Y, Sun J. Galactosylated solid lipid nanoparticles with cucurbitacin B improves the liver targetability, Drug Deliv. 2010 Apr; 17(3):114-22.

5. Qin J, Chen D, Lu W, Xu H, Yan C, Hu H, Chen B, Qiao M, Zhao X. Preparation, characterization, and evaluation of liposomal ferulic acid in vitro and in vivo. Drug Dev Ind Pharm. 2008 Jun; 34(6):602-8.

6. Qiao M, Chen D, Hao T, Zhao X, Hu H, Ma X. Injectable thermosensitive PLGA-PEG-PLGA triblock copolymers-based hydrogels as carriers for interleukin-2. Die Pharmazie. 2008 Jan; 63(1):27-30.

7. HU H., YANG Y., , LIU D., CHEN D The preparation and evaluation in vitro/ vivo of doxorubicin loaded PEG-PAMAM dendrimers, The4thInternationalPharmaceutical Symposium, 2009, 9

8. HU H.; LIU R.; LIU D.; ZHAO X. CHEN D. Studies on Pharmacy Characters and Pharmacokinetics of Oral Apigenin Loaded Solid Lipid Nanoparticle, 2009, 44(6):448-452(in Chinese)

9. H. Hu, H. SONG, D. CHEN, D. LIU. Preparation of oral timed release pellets of ligustrazine hydrochloride, J. Shenyang Pharma. Univ.,2008, 25 (5): 342-346.(in Chinese)

10. H. Hu, D. CHEN, Y. LIU, M. QIAO, X. ZHAO. Preparation and in vitro tumor cells selectivity of sterically stabilized immunoliposomal peptides in bee venom. Acta Pharma. Sinica, 2007, 42(11): 1201-1205. (in Chinese)

11. H. Hu, D. Chen, C. Zhang, Preparation of peptides in bee venom sterically stabilized liposomes, Chin. Pharm. J., 2005, 40 (15): 1160-1163. (in Chinese)

12. H. Hu, H. Song, D. Chen, Y. Ge, Y. Ma, Preparation and optimization of enteric coated omeprazole pellets, Chin. Pharm. J., 2003, 38 (10): 780-781. (in Chinese)

13. LIU R., HU H., CHEN D., QIAO M., LIU D., ZHAO X., Preparation of apigenin solid lipid nanoparticles, Journal of Shenyang Pharmaceutical University, 2009, 26 (5):335-337 (in Chinese)

14. LIU D., HU H., CHEN D., LIU R., ZHAO X., QIAO M., Pharmacokinetics and Tissue Distribution of Apigenin Niosomes, Chinese Pharmaceutical Journal, 2009, 44(13): 1009-1013(in Chinese)

15. XING C., HU H., YANG C., JIN Y., ZHAO X., CHEN D., Optimization of vinpocetine long-circulation liposome formulation by Box-Behnken experimental design, Journal of Shenyang Pharmaceutical University, 2009, 26(10):761-761(in Chinese)

16. YANG Y., HU H., LIU D., JIN Y., JIA L., CHEN D., Synthesis,characterization and property of loading drug of polyamide-amine dendrimers and PEG-poly-amidiamine, Journal of Shenyang Pharmaceutical University, 2009, 26(12):951-955 (in Chinese)