王峰

2003年畢業於曲阜師範大學生命科學院，生命科學專業，2008年在武漢大學獲得生物物理學博士學位。后在美國Cincinnati University進行博士后研究。2014年回國任天津醫科大學基礎醫學院教授，入選天津市"青年千人"計劃，天津市“131”創新型人才，獨立支配經費295萬元。王峰教授，致力於研究端粒與細胞衰老的關係以及端粒酶在腫瘤發生髮展中的關鍵作用。相關工作在PNAS，EMBO.J以及Cell Reports等科研雜誌發表。

2014年6月~今天津醫科大學醫用生物學教研室教授

王峰老師課題組主要研究方向包括：

1）端粒DNA複製的分子機制；

2）端粒DNA高級結構形成對複製性衰老的影響；

3）環境污染引發DNA損傷以及複製性衰老的作用機制；

4）端粒長度縮短對智力發育以及認知水平的影響及機制。

Wang F*, Steward J, Carolyn PM. (2014) Human CST Abundance Determines Recovery from Diverse Forms of DNA Damage and Replication Stress. Cell Cycle; 15;13(22):3488-3498

Kasbek,C., Wang,F ., Price,C.M. (2013) Human TEN1 maintains telomere integrity and functions in genome-wide replication restart. Journal of Biological Chemistry; 288(42): 30139-50

Wang, F ., Tang, M.L., Zeng, Z.X., Wu. R.Y., Xue, Y., Hao, Y.H., Pang, D.W., Zhao, Y., Tan, Z. (2012) Telomere- and telomerase-interacting protein that unfolds telomere G-quadruplex and promotes telomere extension in mammalian cells. Proc Natl Acad Sci U S A 109: 20413-20418

Wang, F ., Stewart, J.A ., Kasbek, C., Zhao, Y., Wright, W.E., Price, C.M. (2012) Human CST has independent functions during telomere duplex replication and C-strand fill-in. Cell Rep. 2:1096-1103

Stewart, J.A., Wang, F., Chaiken, M.F., Kasbek, C., Chastain, P.D., Wright, W.E., Price, C.M. (2012) Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J. 31:3537-3549

Stewart, J.A., Chaiken, M.F., Wang, F., Price, C.M. (2012) Maintaining the end: Roles of telomere proteins in end-protection, telomere replication and length regulation. Mutation Research. 730:12-19

Wang, F., Zhao, Y., Hao, Y., Tan, Z. (2008) Identification of low-abundance alternatively spliced mRNA variants by exon exclusive reverse transcriptase polymerase chain reaction. Anal Biochem 383: 307-310

Kan, ZY., Lin, Y., Wang, F., Zhuang, X.Y., Zhao, Y., Pang, D.W., Hao, Y.H., Tan, Z. (2007) G-quadruplex formation in human telomeric (TTAGGG)4 sequence with complementary strand in close vicinity under molecularly crowded condition. Nucleic Acids. Res. 35: 3646-3653