吳強

1999年-2001年，哈佛大學博士后。

2008年回國前任猶他大學助理教授。

現任上海交通大學特聘教授，系統生物醫學研究院和上海市腫瘤研究所研究員，博士生導師。

著作

Huang H. and Wu, Q*. (2010). Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity. PLoS ONE 5: E9144.

Ying,G., Wu, S., Hou, R., Huang, W., Capecchi, M., Wu, Q*. (2009). Protocadherin Celsr3 is required for interneuron migration in the mouse forebrain. Molecular and Cellular Biology 29:3045-3061.

Wu, S., Ying, G., Wu, Q., and Capecchi, M.R. (2008). A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond. Nature Protocol 3:1056-1076.

Zou, C., Huang, W., Ying, G., and Wu, Q*. (2007). Sequence analysis and expression mapping of the rat clustered protocadherin gene repertoires. Neuroscience 144: 579-603.

Wu, S., Ying, G., Wu, Q., and Capecchi, M.R. (2007). Towards simpler and faster genome-wide mutagenesis in mice. Nature Genetics 39: 922-930.

Li, C. and Wu, Q*. (2007). Evolution of vertebrate multiple variable first exons and structural diversity of drug metabolizing enzymes. BMC Evolutionary Biology 7: 69.

Wu, Q*#. (2005). Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes. Genetics 169:2179-2188.

Zhang, T., Haws, P., and Wu, Q*. (2004) Multiple variable first exons: a mechanism for cell- and tissue- specific gene regulation. Genome Research 14: 70-89.

Tasic, B., Nabholz, C.E., Baldwin, K.K., Kim, Y., Rueckert, E.H., Ribich, S.A., Cramer, P., Wu, Q., Axel, R., and Maniatis T. (2002). Promoter choice determines splice site selection in protocadherin  and  pre-mRNA splicing. Mol. Cell 10: 21-33.

Wu, Q#., Zhang, T., Cheng, J.-F., Kim, Y., Grimwood, J., Schmutz, J., Dickson, M., Noonan, J.P., Zhang, M.Q., Myers, R.M., and Maniatis, T. (2001). Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Genome Research 11: 389-404.

Wu, Q#. and Maniatis, T. (2000). Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. Proc Natl Acad Sci USA 97:3124-3129.

Pohl U., Smith J.S., Tachibana I., Ueki K., Lee H.K., Ramaswamy S., Wu Q., Mohrenweiser H.W., Jenkins R.B., Louis D.N. (2000). EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins. Genomics 63: 255-262.

Wu, Q#. a nd Maniatis, T. (1999) A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97: 779-790.

Wu, Q#. and Krainer, A.R. (1999) AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes. Molecular and Cellular Biology 19: 3225-3236.

Wu, Q#. and Krainer, A.R. (1998) Purine-rich enhancers function in the AT-AC splicing pathway and do so independently of intact U1 snRNP. RNA 4: 1664-1673.

Wu, Q#. and Krainer, A.R. (1997) Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs. RNA 3: 586-601.

Wu, Q#. and Krainer, A.R. (1996) U1-mediated exon definition interactions between AT-AC and GT-AG introns. Science 274: 1005-1008.