常江

男，博士、研究員，博士生導師，美國生物材料協會、國際組織工程學會、紐西蘭顯微鏡學會、澳大利亞/紐西蘭基質生物學學會、中國生物材料學會會員。

1982年畢業於西北輕工業學院化工一系。

1985年赴德國留學，1991年在德國達姆施達特工業大學獲博士學位，從1991年4月至1993年6月在德國盧卑克醫科大學做博士后研究，從事活性人造皮膚作為皮膚創傷修復模型的研究。

1993年7月至1997年6月在紐西蘭奧克蘭大學任研究員，從事軟骨細胞與生物材料相互作用機理方面的研究。1996年獲紐西蘭職業華人傑出成就獎。

1997年至1999年在美國紐約大學受聘為研究助理教授。主要研究課題包括以膠原蛋白材料為載體進行軟骨細胞移植修復軟骨損傷、生物陶瓷活性骨損傷修復材料的研究。

1999年至2000年在美國強生公司損傷修復技術中心任研究員，從事生物材料和骨科組織工程學方面的研究開發工作。

2000年12月獲中國科學院“引進國外傑出人才”（百人計劃）基金，應聘回國，到中國科學院上海硅酸鹽研究所從事科研工作。

（1）可降解生物活性骨修復材料的研究

（2）作為藥物載體的生物材料以及藥物控制釋放的研究

（3）納米生物材料製備技術研究

1. Chengtie Wu. Jiang Chang. Yin Xiao. “Advanced bioactive inorganic materials for bone regeneration and drug delivery" Publisher. CRC Press and Taylor & Francis. January

2. Kaili Lin, Jiang Chang. Chapter 6: Preparation and mechanism of novel bioceramics with controllable morphology and crystal growth,in “Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery”, CRC press, March

3. Jiang Chang, Wenguo Cui, Yue Zhou, Lei Chen, Fabrication of Fibrous Scaffolds for Tissue Engineering by Electrospinning Techniques, Chapter 15 in The Handbook of Intelligent Scaffold for Regenerative Medicine, Ed. Gilson Khang, Publishers: Pan Stanford Publishing

4. Wenguo Cui, Jiang Chang, Paul Dalton, Electrospun Fibers For Drug Delivery, in Comprehensive Biomaterials, Ed. Paul Ducheyne, Kevin E. Healy, Dietmar E. Hutmacher, David E. Grainger and C. James Kirkpatrick, Publisher: Elsevier Science

5. Jiang Chang, Yanling Zhou, Yue Zhou, Surface modification of bioactive glasses, in Bioactive Glasses, Ed. Heimo Ylänen, Publishers: Woodhead Publishing Ltd.

6. Chengtie Wu, Jiang Chang, Hala Zreiqat. “Engineered Ca-Si based ceramics for skeletal tissue reconstruction”. In Book: "Biomaterials for Bone Regenerative Medicine" by editors: N.Sooraj Hussain and J. D. Santos. Publishers: Trans Tech Publishers (Ttp), Switzerland

7. Jiang Chang, Daming Zhang, Lingzhi Ye. “Biodegradable bioceramics/polymer composites for tissue regeneration” in 《Surface Design and Modification of Biomaterials for Clinical Application-Geometry of Material Surfaces, Cell Affinity and Immobilization of CAMs and Tropic Factors》 , Editor: Junzo Tanaka，Publisher: Research Signpost,

8. Jiang Chang, Lei Chen. “Silicate-based bioactive materials for bone regeneration” in Biomaterials in Asia. Ed. Tetsuya Tateishi, World Scientific Publishing Co Pte Ltd

9. Ying-Jie Zhu, Jiang Chang. “Microwave-assisted Synthesis and Processing of Biomaterials” in NanoScience in Biomedicine. Ed. Donglu Shi, Publisher: Springer

1. Xiaoguo Liu, Kaili Lin, Chengtie Wu, Yueyue Wang, Zhaoyong Zou, Jiang Chang*. Multilevel hierarchically ordered artificial biomineral. SMALL

2. Haiyan Li, Ke Xue, Ni Kong, Kai Liu*, Jiang Chang*. Silicate bioceramics enhanced vascularization and osteogenesis through stimulating interactions between endothelia cells and bone marrow stromal cells. Biomaterials

3. Chengtie Wu, Pingping Han, Xiaoguo Liu, Mengchi Xu, Tian Tian, Jiang Chang*, Yin Xiao*. Mussel-inspired β-tricalcium phosphate bioceramics with Ca-P/polydopamine hybrid nanolayer: preparation, formation mechanism and improved cellular bioactivity. Acta Biomaterialia

4. Mengchi Xu, Dong Zhai, Jiang Chang*, Chengtie Wu*. In vitro assessment of 3D-Plotted nagelschmidtite bioceramic scaffolds with varied macropore morphology. Acta Biomaterialia

5. Chengtie Wu, Yinghong Zhou, Mengchi Xu, Pingping Han, Lei Chen, Jiang Chang*, Yin Xiao*. Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity. Biomaterials

6. Chengtie Wu*, Wei Fan, Jiang Chang*. Functional mesoporous bioactive glass nanospheres: synthesis, apatite mineralization, controllable delivery of doxorubicin and inhibitory effect on bone cancer cells. Journal of Materials Chemistry

7. Chengtie Wu, Pingping Han, Mengchi Xu, Xufang Zhang, Yinghong Zhou, Guangda Xue, Jiang Chang*, Yin Xiao*. Nagelschmidtite bioceramics with osteostimulation property: material chemistry activating osteogenic genes and WNT signalling pathway of human bone marrow stromal cells. Journal of Materials Chemistry B

8. Chengtie Wu*, Minghui Zhang, Dong Zhai, Jianding Yu, Yan Liu, Huiying Zhu, Jiang Chang*. Containerless processing for preparation of akermanite bioceramic spheres with homogenous structure, tailored bioactivity and degradation. Journal of Materials Chemistry B

9. Chen Wang, Kaili Lin, Jiang Chang*, Jiao Sun*. Osteogenesis and angiogenesis induced by porous b-CaSiO3/PDLGA compositescaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways. Biomaterials

10. Haiyan Li, Jiang Chang*. Stimulation of proangiogenesis by calcium silicate bioactive ceramic. Acta Biomaterilia.

11. He Xu, Haiyan Li*, Jiang Chang*. Controlled drug release from polymer matrix by patterned electrospun nanofibers with controllable hydrophobicity. Journal of Materials Chemistry B

12. Wanyin Zhai, Hongxu Lu, Chengtie Wu, Lei Chen, Xiaoting Lin, Kawazoe Naoki, Guoping Chen*, Jiang Chang*. Stimulatory effects of the ionic products from Ca-Mg-Si bioceramics on both osteogenesis and angiogenesis in vitro. Acta Biomaterialia

13. Haiyan Li, Jiang Chang*. Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect. Acta Biomaterialia

14. Kaili Lin, Lunguo Xia, Jinbo Gan, Zhiyuan Zhang, Hong Chen*, Xinquan Jiang*, Jiang Chang*. Tailoring the Nanostructured Surfaces of Hydroxya patite Bioceramics to Promote Protein Adsorption, Osteoblast Growth, and Osteogenic Differentiation. ACS Applied Materials& Interfaces

15. Kaili Lin, Lunguo Xia,Haiyan Li, Xinquan Jiang,Haobo Pan,Yuanjin Xu,William W Lu, Zhiyuan Zhang*, Jiang Chang*. Enhanced osteoporotic bone regeneration by strontium-substituted calcium silicate bioactive ceramics. Biomaterials

16. Chengtie Wu, Yinghong Zhou, Jiang Chang*, Yin Xiao*. Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells. Acta Biomaterialia

17. Yan Han, Qiongyu Zeng, Haiyan Li*, Jiang Chang*. The calcium silicate/alginate composite: preparation and evaluation of its behavior as bioactive injectable hydrogels. Acta Biomaterialia

18. Lunguo Xia, Kaili Lin, Xinquan Jiang, Yuanjin Xu, Maolin Zhang, Jiang Chang*, Zhiyuan Zhang*. Enhanced osteogenesis through nano-structured surface design of macroporous hydroxyapatite bioceramic scaffolds via activation of ERK and p38 MAPK signaling pathways. Journal of Materials Chemistry

19. Chengtie Wu, Jiang Chang*, Wei Fan*. Bioactive mesoporous calcium-silicate nanoparticles with excellent mineralization ability, osteostimulation, drug-delivery and antibacterial properties for filling apex root of tooth. Journal of Materials Chemistry

20. Chengtie Wu, Yinghong Zhou, Chucheng Lin, Jiang Chang*, Yin Xiao*. Strontium-containing mesoporous bioactive glass scaffolds with improved osteogenic/cementogenic differentiation of periodontal ligament cells for periodontal tissue engineering. Acta Biomaterialia

21. Meili Zhang, Chengtie Wu, Haiyan Li, Jones Yuen, Jiang Chang*, Yin Xiao*. Preparation, characterization and in vitro angiogenic capacity of cobalt substituted b-tricalcium phosphate ceramics. Journal of Materials Chemistry

22. Zhaoyong Zou, Xiaoguo Liu, Lei Chen, Kaili Lin*, Jiang Chang*. Dental enamel-like hydroxyapatite transformed directly from monetite. Journal of Materials Chemistry

23. Yuandong Dou, Chengtie Wu, Jiang Chang*. Preparation, mechanical property and cytocompatibility of poly (L-lactic acid)/calcium silicate nanocomposites with controllable distribution of calcium silicate nanowires

24. Wanyin Zhai, Hongxu Lu, Lei Chen, Xiaoting Lin, Yan Huang, Kerong Dai, Kawazoe Naoki, Guoping Chen*, Jiang Chang*. Silicate bioceramics induce angiogenesis during bone regeneration. Acta Biomaterialia

25. Botao Song, Chengtie Wu, Jiang Chang*. Dual drug release from electrospun poly(lactic-co-glycolic acid)/mesoporous silica nanoparticles composite mats with distinct release profiles. Acta Biomaterialia

26. Chen Wang, Xue Yang, Kaili Lin, Jianxi Lu, Jiang Chang*, Jiao Sun*.The enhancement of bone regeneration by the combination of osteoconductivity and osteostimulation using composite bioceramics. Acta Biomaterialia

27. Huijie Gu, Fangfang Guo,Xiao Zhou,Lunli Gong, Yun Zhang, Wanyin Zhai, Lei Chen, Lian Cen, Shuo Yin, Jiang Chang*, Lei Cui*. Ionic products from akermanite dissolution stimulate osteogenic differentiation of human adipose-derived stem cells via activation of ERK pathway. Biomaterials

28. Kaili Lin, Yanling Zhou, Yue Zhou, Haiyun Qu, Feng Chen, Yingjie Zhu, Jiang Chang*. Biomimetic hydroxyapatite porous microspheres with co-substituted essential trace elements: Surfactant-free hydrothermal synthesis,enhanced degradation and drug release. Journal of Materials Chemistry

29. Liang Wu, Yuandong Dou, Kaili Lin, Wanyin Zhai, Wenguo Cui, Jiang Chang*. Hierarchically structured nanocrystalline hydroxyapatite assembled hollow fibers as a promising protein delivery system. Chemical Communications

30. Kaili Lin, Xiaoguo Liu, Jiang Chang*, Yingjie Zhu, Facile Synthesis of Hydroxyapatite Nanoparticles, Nanowires and Hollow Nano-structured Microspheres using Similar Structured Hard-precursors. Nanoscale

31. Yuandong Dou, Kaili Lin, Jiang Chang*. Polymer nanocomposites with controllable distribution and arrangement of inorganic nanocomponents. Nanoscale

32. Wanyin Zhai, Xiqin Lü, Jiang Chang*, Yanlin Zhou, Hongfeng Zhang, Quercetin crosslinked porcine heart valve matrix: mechanical property, stability, anti-calcification and cytocompatibility, Acta Biomaterialia

33. Zhiguang Huan, Jiang Chang*. Novel bioactive composite bone cements based on β-tricalcium phosphate-monocalcium phosphate monohydrate composite cement system. Acta Biomaterialia

34. Yan Huang, Xiaogang Jin, Xiaoling Zhang, Hongli Sun, Jinwen Tu, Tingting Tang, Jiang Chang*, Kerong Dai.In vitro and in vivo evaluation of akermanite bioceramics for bone regeneration. Biomaterials

35. Daming Zhang, Jiang Chang*. Electrospinning of Three-Dimensional Nanofibrous Tubes with Controllable Architectures. Nano Letters

36. Qihai Liu, Lian Cen, Shuo Yin, Lei Chen, Guangpeng Liu, Jiang Chang*, Lei Cui*. A comparative study of proliferation and osteogenic differentiation of adipose-derived stem cells on akermanite and β-TCP ceramics, Biomaterials

37. Songfeng Xu, Kaili Lin, Zhen Wang*, Jiang Chang*, Lin Wang, Jianxi Lu, Congqin Ning. Reconstruction of calvarial defect of rabbits using porous calcium silicate bioactive ceramics. Biomaterials

38. Daming Zhang, Jiang Chang*. Patterning of electrospun fibers using electroconductive templates. Advanced Materials

39. Zhiguang Huan, Jiang Chang*. Self-setting properties and in vitro bioactivity of the calcium sulfate hemihydrate/tricalcium silicate composite bone cements. Acta Biomaterialia

40. Faming Zhang, Jiang Chang*, Jianxi Lu, Kaili Lin, Congqin Ning. Bioinspired Structure of Bioceramics for Bone Regeneration in Load Bearing Sites. Acta Biomaterialia

41. Hongli Sun, Chengtie Wu, Kerong Dai*, Jiang Chang*, Tingting Tang, Proliferation and osteoblastic differentiation of human bone marrow-derived stromal cells on akermanite bioactive ceramics. Biomaterials

42. Wanyin Zhai, Jiang Chang*, Kaili Lin, Junyin Wang, Qiang Zhao, Xiaoning Sun. Crosslinking of decellularized porcine heart valve matrix by procyanidins. Biomaterials

43. Wei Xia, Jiang Chang*. Well-ordered mesoporous bioactive glasses (MBG): a promising bioactive drug delivery system. Journal of Controlled Release

44. Chengtie Wu, Jiang Chang*, Junying Wang, Shiyu Ni, Wanyin Zhai. Preparation and Characteristics of a Calcium Magnesium Silicate (Bredigite) Bioactive Ceramic. Biomaterials

45. Wenyuan Zhao, Wanyin Zhai, Zheng Wang, Junying Wang, Jiang Chang*. The self-setting property and in vitro bioactivity of tricalcium silicate. Biomaterials.

46. Haiyan Li, Jiang Chang*. Fabrication and characterization of bioactive wollastonite/PHBV composite scaffolds. Biomaterials