楊燕

教授/博士生導師 /副院長

學位/學歷

博士（中山大學）

工作經歷

2017/06—至今 中山大學，公共衛生學院（深圳）營養與食品衛生學系

2013/01—2014/01 江西省疾病預防控制中心，副主任（中組部博士服務團掛職）

2009/11—2011/09 加拿大多倫多大學病理生理系博士后

2005/07—2017/06 中山大學，公共衛生學院營養學系

營養與慢性非傳染性疾病、血栓性疾病；

營養流行病學；

食品安全

迄今，作為項目負責人共主持國家自然科學基金面上項目4項，多項教育部、廣東省自然科學基金、廣東省科技廳等省部級縱向科研項目以及多項橫向科研項目，指導本科生完成國家級、省級和校級大學生創新項目以及中山大學實驗室開放基金等多項學生科研項目。

1. 2018年度國家自然科學基金面上項目，輔酶Q10經血小板整合素αIIbβ3改善糖脂代謝紊亂的作用及機制研究，主持。

2. 2017年度國家自然科學基金重點項目，膳食花色苷及白藜蘆醇改善糖脂代謝紊亂攝入量－效應研究，參加

3. 2015年度國家自然科學基金面上項目，花色苷對血小板趨化因子調節動脈粥樣硬化炎症反應的影響及機制研究，主持。

4. 2013年度國家自然科學基金面上項目，花色苷經血小板凋亡途徑抗動脈粥樣硬化的研究，主持。

1. F. L. Ya, J. J. Tian, Q. Li, L. Y. Chen, J. R, Y. M. Zhao, J. B. Wan, W. H. Ling, and Y. Yang, "Cyanidin-3-O-β-glucoside, a Natural Polyphenol, Exerts Proapoptotic Effects on Activated Platelets and Enhances Megakaryocytic Proplatelet Formation," J Agr Food Chem (2018). Epub ahead of print.（IF=3.412）

2. B. L. Chen, Y. Q. Chen, B. H. Ma, S. F. Yu, L. Y. Li, Q. X. Zeng, Y. T. Zhou, Y. F. Wu, W. L. Liu, J. B. Wan, Y. Yang, and C. W. Li, "Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 responses and suppressing the IL4Ra-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice," Clin Exp Allergy (2018). Epub ahead of print.（IF=5.158）

3. F. L. Ya, Q. Li, D. L. Wang, S. F. Xie, F. L. Song, R. C. Gallant, Z. Z. Tian, J. B. Wan, W. H. Ling, and Y. Yang, "Cyanidin-3-o-beta-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-kappaB Signalling," Thromb Haemost 118 (7), 1215-1229 (2018). (IF=4.952)

4. P. W. Zhang, C. Yang, H. H. Guo, J. B. Wang, S. Q. Lin, H. M. Li, Y. Yang, and W. H. Ling*, "Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals," J Clin Lipidol 12 (2), 417-427 e415 (2018). (IF=3.580)

5. Y. L. Yao, Y. Q. Chen, R. Adili, T. McKeown, P. G. Chen, G. H. Zhu, D. Li, W. H. Ling, H. Y. Ni*, and Y. Yang, "Plant-based Food Cyanidin-3-Glucoside Modulates Human Platelet Glycoprotein VI Signaling and Inhibits Platelet Activation and Thrombus Formation," J Nutr 147 (10), 1917-1925 (2017). (IF=4.398)

6. W. Q. Yang, X. Chen, Y. Liu, M. Chen, X. W. Jiang, T. R. Shen, Q. Li, Y. Yang, and W. H. Ling*, "N-3 polyunsaturated fatty acids increase hepatic fibroblast growth factor 21 sensitivity via a PPAR-gamma-beta-klotho pathway," Mol Nutr Food Res 61 (9) (2017). (IF=5.151)

7. W. Q. Yang, X. Chen, M. Chen, Y. P. Li, Q. Li, X. W. Jiang, Y. Yang, and W. H. Ling*, "Fish oil supplementation inhibits endoplasmic reticulum stress and improves insulin resistance: involvement of AMP-activated protein kinase," Food Funct 8 (4), 1481-1493 (2017). (IF=3.289)

8. X. D. Zhang, Y. N. Zhu, F. L. Song, Y. L. Yao, F. L. Ya, D. Li, W. H. Ling, and Y. Yang, "Effects of purified anthocyanin supplementation on platelet chemokines in hypocholesterolemic individuals: a randomized controlled trial," Nutr Metab (Lond) 13, 86 (2016). (IF=3.483)

9. F. L. Song, Y. N. Zhu, Z. Y Shi, J. J Tian, X. J Deng, J. Ren, M. C. Andrews, H. Y. Ni, W. H. Ling, and Y. Yang, "Plant food anthocyanins inhibit platelet granule secretion in hypercholesterolaemia: Involving the signalling pathway of PI3K-Akt," Thromb Haemost 112 (5), 981-991 (2014). (IF=4.952)

10. Z. X. Li, X. R. Li, Y. Zhang, X. Feng, F. Yang, D. F. Su, J. Qiu, W. H. Ling, and Y. Yang, "Erythrocyte membrane fatty acid composition is related to overloaded plasma ferritin in Chinese males with angiographic coronary artery disease," Food & Function 4 (10), 1535-1542 (2013). (IF=3.289)

11. Y. Yang, Z. Y. Shi, A. Reheman, J. W. Jin, C. L. Li, Y. M. Wang, M. C. Andrews, P. G. Chen, G. H. Zhu, W. H. Ling, and H. Y. Ni*, "Plant Food Delphinidin-3-Glucoside Significantly Inhibits Platelet Activation and Thrombosis: Novel Protective Roles against Cardiovascular Diseases," Plos One 7 (5) (2012). (IF=2.766)

12. Y. N. Zhu, W. H. Ling, H. H. Guo, F. L. Song, Q. Y. Ye, T. B. Zou, D. Li, Y. Zhang, G. L. Li, Y. J. Xiao, F. Q. Liu, Z. X. Li, Z. Y. Shi, and Y. Yang, "Anti-inflammatory effect of purified dietary anthocyanin in adults with hypercholesterolemia: A randomized controlled trial," Nutr Metab Cardiovas 23 (9), 843-849 (2013). (IF=3.318)

13. Y. Yang, M. C. Andrews, Y. Hu, D. L. Wang, Y. Qin, Y. N. Zhu, H. Y. Ni, and W. H. Ling, "Anthocyanin Extract from Black Rice Significantly Ameliorates Platelet Hyperactivity and Hypertriglyceridemia in Dyslipidemic Rats Induced by High Fat Diets," J Agr Food Chem 59 (12), 6759-6764 (2011). (IF=3.412)

1.楊燕(7/10), 膳食多酚類活性物質防治代謝性疾病的基礎及應用研究, 中華醫學會, 科技進步, 二等獎, 2017.1

2.楊燕(7/10), 膳食多酚類活性物質防治代謝性疾病的基礎及應用研究, 廣東省科學技術獎, 二等獎, 2017.2

1.徐培林, 葛怡琛, 楊燕, 血小板增進蛋白及其應用, 2008.11, 中國, CN100432102C

2.Peilin Xu, Yichen Ge, Yan Yang, Platelet promoting protein and the usage thereof, Sep 2011, USA, US 8012927 B2

1.編委：全國高等學校教材《預防醫學》第七版，人民衛生出版社, 2018年

2.編委：全國高等醫學數字化規劃教材（國家醫學電子書包）《預防醫學》第一版，軍醫出版社, 2016年

3.編委：全國高等學校長學制臨床專業規劃教材《預防醫學》第三版，人民衛生出版社, 2015年

4.編委：全國高等學校長學制臨床專業規劃教材《預防醫學學習指導及習題集》第一版，人民衛生出版社，2015年

5.編委：全國高等學校長學制臨床專業規劃教材《預防醫學在線課堂》第三版，人民衛生出版社，2015年

6.編委：全國高等學校教材《衛生學概論》第一版，人民衛生出版社，2012年

7.編委：《腫瘤營養》，第一版，人民衛生出版社，2012年

1. 廣東省營養學會第五屆理事會 常務理事

2. 廣東省營養學會腸道菌群與營養健康專業委員會 副主任委員

3. Molecular Nutrition & Food Research，Journal of Agriculture and Food Chemistry，International Journal of Women’s Health，Central European Journal of Biology等多個國際期刊以及國內學術期刊審稿人