譚斌

◆ 2010.3年至2012.9年，博士后, 美國斯克普斯研究所（The Scripps Research Institute）。

◆ 2012年9月至今，副教授，南方科技大學化學系。

◆ 2010年，獲得新加坡南洋理工大學哲學博士學位 (有機化學)。

◆ 2005年，獲得廈門大學理學碩士學位 (有機化學)。

◆ 2001年，獲得湖南科技大學理學學士學位 (化學教育)。

◆ 核心骨架結構導向的有機催化不對稱合成。

◆ 現代催化體系和綠色合成全新方法的開發。

◆ 金屬與有機催化組成的協同催化體系拓展。

◆ 手性藥物的開發和天然產物的策略全合成。

代表性研究成果：（獨立工作以後從2013年7月至今）

24. Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones.Yong-Bin Wang, Sheng-Cai Zheng, Yu-Mei Hu & Bin Tan. 2017, , 15489

23. Organocatalytic atropselective synthesis of axially chiral styrenes. Sheng-Cai Zheng, San Wu, Qinghai Zhou, Lung Wa Chung, Liu Ye & Bin Tan. 2017, , 15238.

22. Highly Atroposelective Synthesis of Arylpyrroles by Catalytic Asymmetric Paal–Knorr Reaction. Lei Zhang, Jian Zhang, Ji Ma, Dao-Juan Cheng, and Bin Tan*. , 2017, 139 (5), 1714–1717.

21. Phosphoric Acid-Catalyzed Asymmetric Synthesis of SPINOL Derivatives. Shaoyu Li, Ji-Wei Zhang, Xian-Lin Li, Dao-Juan Cheng, and Bin Tan*.J. Am. Chem. Soc., 2016, 138 (50), 16561–16566.

20.Construction of Tropane Derivatives by the Organocatalytic Asymmetric Dearomatization of Isoquinolines.Jin-Hui Xu, Sheng-Cai Zheng, Ji-Wei Zhang, Xin-Yuan Liu, and Bin Tan*. 2016, 55, 11834–11839.

19. Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction.Ji-Wei Zhang,Jin-Hui Xu,Dao-Juan Cheng,Chuan Shi,Xin-Yuan Liu* &Bin Tan*.Nature Communications., 2016, 7, 10677.

18. Atroposelective Synthesis of Axially Chiral Biaryldiols via Organocatalytic Arylation of 2-Naphthols. Ye-Hui Chen,Dao-Juan Cheng,Jian Zhang,Yong Wang,Xin-Yuan Liu*, andBin Tan*.J. Am. Chem. Soc., 2015,137(48), 15062–15065.

17.Phosphoric Acid-Catalyzed Asymmetric Classic Passerini Reaction. Jian Zhang,Shao-Xia Lin,Dao-Juan Cheng,Xin-Yuan Liu*, andBin Tan*.J. Am. Chem. Soc., 2015,137(44),14039–14042.

16. Asymmetric Construction of Spirooxindoles by Organocatalytic Multicomponent Reactions Using Diazooxindoles. Ming-Yue Wu,Wei-Wei He, Xin-Yuan Liu*, Bin Tan*.Angew.chem. Int. Ed.2015,54,9409–9413.

15. Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid. Dao-Juan Cheng, Liang Yan, Shi-Kai Tian,* Ming-Yue Wu, Lu-Xin Wang, Zi-Li Fan, Sheng-Cai Zheng, Xin-Yuan Liu,* and Bin Tan*. Angew. Chem. Int. Ed.2014,53, 3684–3687.

14. Zhi-Jia Fang, Sheng-Cai Zheng, Zhen Guo, Jing-Yao Guo, Bin Tan,* Xin-Yuan Liu*, Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation. Angew. Chem. Int. Ed. 2015, 54, DOI: 10.1002/anie. 201503207.

13. Jin-Shun Lin, Peng Yu, Lin Huang, Pan Zhang, Bin Tan,* Xin-Yuan Liu*, Brønsted Acid-Catalyzed Asymmetric Hydroamination of Alkenes: Synthesis of Pyrrolidines Bearing a Tetrasubstituted Carbon Stereocenter. Angew. Chem. Int. Ed. 2015, 54, 7847.

12. Peng Yu, Sheng-Cai Zheng, Ning-Yuan Yang, Bin Tan,* Xin-Yuan Liu*，Phosphine-Catalyzed Remote β-C-H Functionalization of Amine Triggered by Trifluoromethylation of Alkene: One-Pot Synthesis of Bistrifluoromethylated Enamides and Oxazoles. Angew. Chem. Int. Ed. 2015, 54, 4041.

11. Peng Yu, Jin-Shun Lin, Lei Li, Sheng-Cai Zheng, Ya-Ping Xiong, Li-Jiao Zhao, Bin Tan*,and Xin-Yuan Liu* “Enantioselective C-H Bond Functionalization Triggered by Radical Trifluoromethylation of Unactivated Alkene” Angew. Chem. Int. Ed. 2014, 53, 11890.

10. Lin Huang, Jin-Shun Lin, Bin Tan,* Xin-Yuan Liu*, Alkene Trifluoromethylation-Initiated Remote α-Azidation of Carbonyl Compounds toward Trifluoromethyl γ-Lactam and Spirobenzofuranone-lactam. ACS Catal. 2015, 5, 2826.

9. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Metal-Free Direct 1,6- and 1,2-Difunctionalization Triggered by Radical Trifluoromethylation of Alkenes. Org. Lett. 2015, 17, 1589-1592.

8. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Trifluoromethylation-Initiated Remote Cross-Coupling of Carbonyl Compounds to Form Carbon–Heteroatom/Carbon Bonds. Chem. Eur. J. 2015, 21, 6718.

7. Lei Li, Jing-Yao Guo, Su Chen, Tao Wang, Bin Tan* and Xin-Yuan Liu* “Amide Groups Switch Selectivity: C-H Trifluoromethylation of α,β-Unsaturated Amides and Subsequent Asymmetric Transformation” Org. Lett., 2014, 16, 6032.

6. Jin-Shun Lin, Xiang-Geng Liu, Xiao-Long Zhu, Bin Tan* and Xin-Yuan Liu* “Copper-Catalyzed Aminotrifluoromethylation of Unactivated Alkenes with TMSCF3: Construction of Trifluoromethylated Azaheterocycles” J. Org. Chem. 2014, 79, 7084.

5. Xing-Li Zhu, Jin-Hui Xu, Dao-Juan Cheng, Li-Jiao Zhao, Xin-Yuan Liu* and Bin Tan* “In Situ Generation of Electrophilic Trifluoromethylthio Reagents for Enantioselective Trifluoromethylthiolation of Oxindoles” Org. Lett. 2014, 16, 2192.

4. Ya-Ping Xiong, Ming-Yue Wu, Xiang-Yu Zhang, Can-Liang Ma, Lin Huang, Li-Jiao Zhao, Bin Tan* and Xin-Yuan Liu* “Direct Access to α-CF3-enones via Efficient Copper-Catalyzed Trifluoromethylation of Meyer-Schuster Rearrangement” Org. Lett. 2014, 16, 1000.

3. Lei Li, Min Deng, Sheng-Cai Zheng, Ya-Ping Xiong, Bin Tan* and Xin-Yuan Liu.* “Metal-Free Direct Intramolecular Carbotrifluoromethylation of Alkenes to Functionalized Trifluoromethyl Azaheterocycles” Org. Lett. 2014, 16, 504.

2. Jin-Shun Lin, Ya-Ping Xiong, Can-Liang Ma, Li-Jiao Zhao, Bin Tan* and Xin-Yuan Liu*. “Efficient Copper-Catalyzed Direct Intramolecular Aminotrifluoromethylation of Unactivated Alkenes with Diverse Nitrogen-Based Nucleophiles” Chem. Eur. J. 2014, 20, 1332.

1. Dao-Juan Cheng, Yoshihiro Ishihara, Bin Tan* and Carlos F. Barbas, III* “Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies”.ACS Catal. 2014, 4, 743

代表性研究成果：（獨立工作以前，只列第一作者，所有文章的影響因子都大於5.5）

1.Tan. B.; Toda N; Barbas III, C. F. Organocatalytic Amidation and Esterification of Aldehydes with Activating Reagents by a Cross-coupling Strategy. Angew. Chem. Int. Ed. 2012, 51, 12538-12541.

2.Tan. B.; Hernández-Torres, G.; Barbas III, C. F. Rational Design Enables Amide Nucleophiles for Organocatalytic Asymmetric Michael Reactions. Angew. Chem. Int. Ed. 2012, 51, 5381-5385.

3.Tan, B.; Zeng, X.; Leong, W. W. Y.; Shi, Z.; Barbas III, C.F.; Zhong, G. Core Structure-Based Design of a Novel Organocatalytic [3+2] Cycloaddition: Highly efficient and Stereocontrolled Synthesis of Spirocyclic Oxindoles. Chem. Eur. J. 2012, 18, 63-67.

4.Tan, B.; Candeias, N.; Barbas III, C.R. Construction of Bispirooxindoles Containing three Quaternary Stereocentres in a Cascade Using a Single Multifunctional Organocatalyst. Nature Chem. 2011, 3, 473-477.

5.Tan B.; Hernández-Torres, G.; Barbas III, C.F. J. Highly Efficient Hydrogen-Bonding Catalysis of the Diels-Alder Reaction of 3-Vinylindoles and Methyleneindolinones Provides Carbazolespirooxindole Skeleton. Am. Chem. Soc. 2011, 131, 12354-12358.

6.Tan, B.; Candeias, N.; Barbas III, C.F. J. Core-Structure-Motivated Design of a Phosphine-Catalyzed [3+2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles. Am. Chem. Soc. 2011, 131, 4672-4675.

7.Tan, B.; Zeng, X.; Chua, P. J.; Zhong, G. Rational Design of Domino Michael-Henry Reaction: Direct Construction of Bicyclo[3.2.1]octane Skeletons with Four Stereogeric Centers. Org. Lett. 2010, 12, 2682-2685.

8.Tan, B.; Zhu, D.; Zhang, L.; Dai, L.; Chua, P. J.; Shi, Z.; Zeng, X; Zhong, G. Water More than Just a Green Solvent: A Stereoselective One-Pot Access to All Chiral Tetrahydronaphthalenes in Aqueous Media. Chem. Eur. J. 2010, 16, 3842-3848.

9.Tan, B.; Shi. Z.; Chua, P. J.; Li, Y.; Zhong, G. Unusual Domino Michael/Aldol Condensation Reactions Employing Oximes as N-Selective Nucleophiles: Synthesis of N-Hydroxypyrroles. Angew. Chem. Int. Ed. 2009, 48, 758-761.

10.Tan, B.; Zhang, X.; Chua, P. J.; Zhong, G. Recyclable organocatalysis: highly enantioselective Michael addition of 1,3-diaryl-1,3-propanedione to nitroolefins (Cover Article). Chem. Commun. 2009, 779-781

11.Tan, B.; Zeng, X.; Lu, Y.; Chua, P. J.; Zhong, G. Rational Design of Organocatalyst: Highly Stereoselective Michael Addition of Cyclic Ketones to Nitroolefins. Org. Lett. 2009, 11, 1931-1933.

12.Tan, B.; Chua, P. J.; Zeng, X.; Lu, M.; Zhong, G. A Highly Diastereo- and Enantioselective Synthesis of Multisubstituted Cyclopentanes with Four Chiral Carbons by the Organocatalytic Domino Michael-Henry Reaction. Org. Lett. 2008, 10, 3489-3492.

13.Tan, B.; Shi, Z.; Chua, P. J.; Zhong, G. Control of Four Stereocenters in an Organocatalytic Domino Double Michael Reaction: Efficient Synthesis of Multisubstituted Cyclopentanes. Org. Lett. 2008, 10, 3425-3428.

14.Tan, B.; Chua, P. J.; Li, Y.; Zhong, G. Organocatalytic Asymmetric Tandem Michael-Henry Reactions: A Highly Stereoselective Synthesis of Multifunctionalized Cyclohexanes with Two Quaternary Stereocenters. Org. Lett. 2008, 10, 2437-2440.

1.Zhong, G.; Tan, B.; Zhang, X.; Chua, P. J. Process for highly enantioselective Michael addition of 1,3-diaryl-1,3-propanedione to nitroolefins using using cinchona alkaloids as recyclable organocatalysts. U.S. Pat. Appl. Publ. (2012), US 20120004424 A1 20120105.

2.Zhong, G,; Tan, B.; Shi, Z. Chua, P. J. Process of forming pyrrole compounds. U.S. Pat. Appl. Publ. (2011), US 20110124881 A1 20110526.

3.Zhong, G,;Tan, B.; Chua, P. J.; Shi, Z. Process for preparation of chiral cycloalkane derivatives by asymmetric cyclization. U.S. Pat. Appl. Publ. (2010), US 20100298576 A1 20101125.

4.Zhong, G.; Lu, M.; Zhu, D.; Lu, Y.; Hou, Y.; Tan, B. Processes for enantioselective preparation of an aminoxy compound and an 1,2-oxazine compound. U.S. Pat. Appl. Publ. (2011), US 20110224429 A1 20110915.

◆ 2013年，深圳市海外高層次人才“孔雀計劃”入選者。

◆ 2009年，國家優秀自費留學生獎學金。