曹毅

四川大學生命科學學院教授

曹毅是四川大學生命科學學院教授,主要從事微生物資源與代謝工程、微生物生物能源、功能基因組與生物信息、畜用生物製劑與生物安全等領域的研究工作。

人物經歷


學位簡歷

1989年內蒙古民族大學獲學士學位
1992年甘肅農業大學獲碩士學位
1998年甘肅農業大學獲博士學位

工作簡歷

1993年 四川大學生命科學學院 講師
1995年 四川大學生命科學學院 副教授
2002年 四川大學生命科學學院 教授
2005年 教育部新世紀優秀人才,四川省傑出青年學科帶頭人和四川省學術及技術帶頭人
2006年 四川省生物信息與代謝工程共享實驗平台 主任
2009年 微生物與代謝工程四川省重點實驗室 主任
2010年 國家科技部農業預備項目評審專家
2011年 中國微生物學會基礎微生物委員會 理事
2012年 四川省科技青年聯合會 理事

社會職務

●微生物與代謝工程四川省重點實驗室 主任
●四川省生物信息與代謝工程共享實驗平台 主任
●中國微生物學會基礎微生物委員會 理事
●四川省科技青年聯合會 理事
●教育部新世紀優秀人才
●四川省學術及技術帶頭人
●Electronic Journal of Biotechnology, Current Microbiology, World Journal ofMicrobiology & Biotechnology, African Journal of Microbiology Research評審專家
●國家科技部、國家自然科學基金委、四川省科技廳、江蘇省科技廳、天津市科技廳、成都市科技局項目評審專家

研究方向


主要從事微生物資源與代謝工程、微生物生物能源、功能基因組與生物信息、畜用生物製劑與生物安全等領域的研究工作。

主要貢獻


1. Cao Y, Jin N, Xu H, Liu Y, Zhu WH, Li XR, Qiao DR, Cao Y.Characterization and alternative splicing of the complex I 19-kD subunit in Dunaliella salina: expression and mutual correlation of splice variants under diverse stresses.Biosci Biotechnol Biochem. 2010;74(5):1073-8.
2. Liu Q, Jiang C, Xu Z, Xu H, Zhao R, Qiao D, Cao Y. Analysis of protein interaction network and function of Staphylococcus aureus].Wei Sheng Wu Xue Bao. 2009 Jan 4;49(1):56-63.
3. He Q, Qiao D, Bai L, Zhang Q, Yang W, Li Q, Cao Y.Cloning and characterization of a plastidic glycerol 3-phosphate dehydrogenase cDNA from Dunaliella salina.J Plant Physiol. 2007 Feb;164(2):214-20.
4. Qinghua H, Dairong Q, Qinglian Z, Shunji H, Yin L, Linhan B, Zhirong Y, Yi C.Cloning and expression studies of the Dunaliella salina UDP-glucose dehydrogenase cDNA.DNA Seq. 2005 Jun;16(3):202-6.
5. Chen C, Bai LH, Qiao DR, Xu H, Dong GL, Ruan K, Huang F, Cao Y.Cloning and expression study of a putative carotene biosynthesis related (cbr) gene from the halotolerant green alga Dunaliella salina. Mol Biol Rep. 2008 Sep;35(3):321-7.
6. Liu Y, Qiao DR, Zheng HB, Dai XL, Bai LH, Zeng J, Cao Y.Cloning and sequence analysis of the gene encoding 19-kD subunit of Complex I from Dunaliella salina.Mol Biol Rep. 2008 Sep;35(3):397-403.
7. Yi Y, Yi C, Qian L, Min L, Long C, Linhan B, Zhirong Y, Dairong Q.Cloning and sequence analysis of the gene encoding (6-4)photolyase from Dunaliella salina. Biotechnol Lett. 2006 Mar;28(5):309-14.
8. Zhang F, Qiao D, Xu H, Liao C, Li S, Cao Y.Cloning, expression, and characterization of xylose reductase with higher activity from Candida tropicalis. J Microbiol. 2009 Jun;47(3):351-7.
9. Yi Y, Qiao D, Bai L, Xu H, Li Y, Wang X, Cao Y.Cloning, expression, and functional characterization of the Dunaliella salina 5-enolpyruvylshikimate-3-phosphate synthase gene in Escherichia coli. J Microbiol. 2007 Apr;45(2):153-7.
10. Cao Y, Yu RQ, Liu Y, Zhou HX, Song LL, Cao Y, Qiao DR Design, recombinant expression, and antibacterial activity of the cecropins-melittin hybrid antimicrobial peptides.Curr Microbiol. 2010 Sep;61(3):169-75.
11. Cheng L, Qiao DR, Lu XY, Xiong Y, Bai LH, Xu H, Yang Y, Cao Y.Identification and expression of the gene product encoding a CPD photolyase from Dunaliella salina. J Photochem Photobiol B. 2007 May 25;87(2):137-43.
12. Liang X, Qiao D, Huang M, Yi X, Bai L, Xu H, Wei L, Zeng J, Cao Y.Identification of a gene encoding the light-harvesting chlorophyll a/b proteins of photosystem I in green alga Dunaliella salina. DNA Seq. 2008 Apr;19(2):137-45.
13. Wei L, Cao Y, Liang X, Liu Y, Deng T, Bai L, Qiao D.Identification of two genes encoding the major light-harvesting chlorophyll a/b proteins of photosystem II in green alga Dunaliella salina. DNA Seq. 2006 Oct;17(5):370-7.
14. Yang W, Cao Y, Sun X, Huang F, He Q, Qiao D, Bai L.Isolation of a FAD-GPDH gene encoding a mitochondrial FAD-dependent glycerol-3-phosphate dehydrogenase from Dunaliella salina. J Basic Microbiol. 2007 Jun;47(3):266-74.
15. Liu Y, Jiang Y, Qiao DR, Cao Y. [The mechanism and application of posttranscriptional gene silencing]. Sheng Wu Gong Cheng Xue Bao. 2002 Jan;18(2):140-3.
16. Zhu W, Qiao D, Huang M, Yang G, Xu H, Cao Y.Modifying thermostability of appA from Escherichia coli. Curr Microbiol. 2010 Oct;61(4):267-73.
17. Yan Lv X, Rong Qiao D, Xiong Y, Xu H, You FF, Cao Y, He X, Cao Y.Photoreactivation of (6-4) photolyase in Dunaliella salina. FEMS Microbiol Lett. 2008 Jun;283(1):42-6.
18. Zhang F, Xu H, Cao Y, Wen T, Lin J, Ma G, Qiao D, Cao Y.Role of Lys281 in the Dunaliella salina (6-4) photolyase reaction. Curr Microbiol. 2011 Jan;62(1):146-51.
19. Xie J, Song L, Li X, Yi X, Xu H, Li J, Qiao D, Cao Y.Site-directed mutagenesis and thermostability of xylanase XYNB from Aspergillus niger 400264. Curr Microbiol. 2011 Jan;62(1):242-8.
20. Rui Zhao, Yu Cao, Hui Xu, Linfeng Lv, Dairong Qiao, Yi Cao,Analysis of Expressed Sequence Tags From The Green Alga Dunaliella Salina (Chlorophyta),Journal of Phycology,2011,152(2):139-147
21.Guihong Lan, Zengting Li, Hui zhang, Changjun Zou, Dairong Qiao and Yi Cao,Relationship of microbial diversity from recycled injection water and high-temperature petroleum reservoirs analyzed by polymerase chain reaction denaturing gradient gel electrophoresis (PCR-DGGE),African,Journal of Biotechnology,2011,10(53):11004-11010
22.Guihong Lan, Zengting Li, Hui zhang, Changjun Zou, Dairong Qiao and Yi Cao,Enrichment and diversity analysis of the thermophilic microbes in a high temperature petroleum reservoir,African Journal of Microbiology Research,2011,5(14):1850-1857
23.Shi Lin Li, Shun Li Feng, Zeng Ting Li, Hui Xu, Ying Peng Yu, Dai Rong Qiao and Yi Cao,Isolation, identification and characterization of oleaginous fungi from the soil of Qinghai Plateau that utilize D-xylose,African,Journal of Microbiology Research,2011,5(15):2075-2081.
24.Yu-Zhi Miao, Qiang Lin, Yu Cao, Gui-Hua He, Dai-Rong Qiao, Yi Cao,xtraction of water-soluble polysaccharides (WSPS) from Chinese truffle and its application in frozen yogurt,Carbohydrate Polymers,2011,86:566–573.
25. Jing Li, Shu Zhang, Guanghua Liu, Rui Zhao, Hui Xu, Dairong Qiao and Yi Cao,Separation and identification of lipase – producing strains and immobilized transesterification efficiency,African Journal of Microbiology Research,2010,4(6):448-453
26. Jing Li, Shijie Chen, Lin Li, Yingpeng Yu, Zhongan Fei, Dairong Qiao and Yi Cao,Approach of directed evolution of microbial lipases and biodiesel catalysis,African Journal of Microbiology Research,2012,6(3) :637-642
27. Yan-Li Du, Yu Cao, Fang Lu, Fang Li, Yi Cao, Xiu-Li Wang, Yu-Zhong Wang, Biodegradation behaviors of thermoplastic starch (TPS) and thermoplastic dialdehyde starch (TPDAS) under controlled composting conditions, Polymer Testing, 2008, 27(8):924-930
28. Qinghua He; Dairong Qiao; Qinglian Zhang; Yin Li; Hui Xu1; Liang Wei; Ying Gu; Yi Cao, Cloning and expression study of a putative high-affinity nitrate transporter gene from Dunaliella salina ,Journal of Applied Phycology, 2004 , 16(5):395-400
29. Gaopeng Lei, Dairong Qiao, Linhan Bai, Hui Xu and Yi Cao, Isolation and characterization of a mitogen-activated protein kinase gene in the halotolerant alga Dunaliella salina, 2007, 20(1):13-17
30. W. M. Chen, N. Jin, Y. Shi, Y. Q. Su, B. J. Fei, W. Li, D. R. Qiao and Y. Cao, Coordinate expression of light-harvesting chlorophyll a/b gene family of photosystem II and chlorophyll a oxygenase gene regulated by salt-induced phosphorylation in Dunaliella salina, 2010, 48(3):355-360
31. Liang Wei, Yi Cao, Linhan Bai, Xue Liang, Tingting Deng, Jing Li, Dairong Qiao. Cloning and expression of a gene coding for the major light-harvesting chlorophyll a/b protein of photosystem II in the green alga Dunaliella salina. Journal of Applied Phycology, 2007, 19: 89-94.
先後主持科技部國家轉基因產業化專項、883、973、科技攻關,支撐計劃、基礎性工作專項、國際合作項目,國家自然科學基金,教育部重點項目,四川省支撐計劃、四川省傑出青年基金及成都市科技攻關項目等研究工作。
申請和獲得11項發明專利,出版教材1部,編寫國家微生物資源平台描述規範等。建立了四川省微生物資源保藏中心、四川省生物信息與代謝工程共享實驗平台和微生物與代謝工程四川省重點實驗室。

獲獎記錄


獲得四川省科技進步獎。