楊帆

楊帆（1982-），漢族，男，博士，河北秦皇島人。2007年7月畢業於瀋陽農業大學動物醫學專業，獲得“校優秀畢業生”榮譽稱號；同年9月，開始在華南農業大學獸醫學院攻讀基礎獸醫學碩士學位，研究方向為獸醫藥理學與毒理學，主要從事獸葯新製劑研究；2009年9月提前攻讀博士學位，專業為基礎獸醫學，研究方向為獸醫藥理學與毒理學，主要從事了藥物代謝、獸醫藥物代謝動力學、獸葯殘留檢測及獸葯新製劑開發等研究，期間參與了973項目“畜禽產品中有害物質的消長規律研究”（2009CB118805）第五子項目、國家自然基金項目“鴨疫里氏桿菌耐葯分子機制的研究和快速檢測方法的建立”（31072169）和十一五科技支撐項目“獸用抗菌藥物新製劑的研製與應用”（2006BAD31B06）等研究。

自2012年7月起，到河南科技大學動物科技學院工作，主要從事獸醫藥劑學、獸葯殘留檢測和獸醫藥物代謝動力學的教學和科研工作，研究方向為獸醫藥物代謝動力學、獸葯殘留檢測、獸醫新製劑開發。曾在《Br Poult Sci》、《J Vet Sci》、《J Vet Pharmacol Ther》、《Food Addit Contam Part A Chem Anal Control Expo Risk Assess》、《Res Vet Sci》、《Vet Microbiol》、《J Chromatogr B Analyt Technol Biomed Life Sci》及《Agricultural Sciences in China》等國際SCI收錄期刊上發表論文近20篇。近五年來發表相關論文如下：

1.Yang, F., Sun, N., Zhao, Z.S., Wang, G.Y. & Wang, M.F. (2015) Pharmacokinetics of doxycycline after a single intravenous, oral or intramuscular dose in Muscovy ducks (Cairina moschata). Br Poult Sci, 56(1), 137-142

2.Yang, F., Sun, N., Liu, Y.M. & Zeng, Z.L. (2015) Estimating danofloxacin withdrawal time in broiler chickens based on physiologically based pharmacokinetics modeling. J Vet Pharmacol Ther, 38(2), 174-182.

3.Yang, F., Kang, J., Yang, F., Zhao, Z., Kong, T. & Zeng, Z. (2015) Preparation and evaluation of an enrofloxacin microsphere and its tissue distribution in rats. J Vet Sci. ( published online)

4.Yang, F., Yang, Y.R., Wang, L., Huang, X.H., Qiao, G. & Zeng, Z.L. (2014) Estimating marbofloxacin withdrawal time in broiler chickens using a population physiologically based pharmacokinetics model. J Vet Pharmacol Ther, 37(6), 579-588.

5.Yang, F., Li, Z.L., Shan, Q. Zeng, Z.L. (2014) Pharmacokinetics of doxycycline in tilapia (Oreochromis aureus × Oreochromis niloticus) after intravenous and oral administration. J Vet Pharmacol Ther, 37(4), 388-393.

6.Yang, F., Huang, X. H., Li, G. H., Ni, H. J., Zhao, Y. D., Ding, H. Z. & Zeng, Z. L. (2013) Estimating tulathromycin withdrawal time in pigs using a physiologically based pharmacokinetics model. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 30(7), 1255-1263.

7.Yang, F., Li, G. H., Meng, X. B., Wang, L. Q., Huang, X. H., Shan, Q., Zeng, D. P., Ding, H. Z. & Zeng, Z. L. (2013) Pharmacokinetic interactions of flunixin meglumine and doxycycline in broiler chickens. J Vet Pharmacol Ther, 36(1), 85-88.

8.Yang, F., Sun, N., Sun, Y. X., Shan, Q., Zhao, H. Y., Zeng, D. P. & Zeng, Z. L. (2013) A physiologically based pharmacokinetics model for florfenicol in crucian carp and oral-to-intramuscular extrapolation. J Vet Pharmacol Ther, 36(2), 192-200.

9.Yang, F., Liu, H. W., Li, M., Ding, H. Z., Huang, X. H. & Zeng, Z. L. (2012) Use of a monte carlo analysis within a physiologically based pharmacokinetic model to predict doxycycline residue withdrawal time in edible tissues in swine. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 29(1), 73-84.

10.Li, G., Yang, F. (共同第一作者), He, L., Ding, H., Sun, N., Liu, Y., Liu, Y., Shan, Q., Li, Y. & Zeng, Z. (2012) Pharmacokinetics of mequindox and its metabolites in rats after intravenous and oral administration. Res Vet Sci, 93(3), 1380-1386.

11.Shan, Q., Yang, F., Wang, J., Ding, H., He, L. & Zeng, Z. (2014) Pharmacokinetic/pharmacodynamic relationship of cefquinome against pasteurella multocida in a tissue-cage model in yellow cattle. J Vet Pharmacol Ther, 37(2):178-185.

12.Shan, Q., Wang, J., Yang, F., Ding, H., Liang, C., Lv, Z., Li, Z. & Zeng, Z. (2013) Pharmacokinetic/pharmacodynamic relationship of marbofloxacin against pasteurella multocida in a tissue-cage model in yellow cattle. J Vet Pharmacol Ther, 37(3):222-230.

13.Li, Y., Zhao, N., Zeng, Z., Gu, X., Fang, B., Yang, F., Zhang, B. & Ding, H. (2013) Tissue deposition and residue depletion of cyadox and its three major metabolites in pigs after oral administration. J Agric Food Chem, 61(39): 9510-9515.

14.Sun, N., Liu, J. H., Yang, F., Lin, D. C., Li, G. H., Chen, Z. L. & Zeng, Z. L. (2012) Molecular characterization of the antimicrobial resistance of riemerella anatipestifer isolated ducks. Vet Microbiol, 158(3-4), 376-83.

15.Ding, H., Liu, Y., Zeng, Z., Si, H., Liu, K., Liu, Y., Yang, F., Li, Y. & Zeng, D. (2012) Pharmacokinetics of mequindox and one of its major metabolites in chickens after intravenous, intramuscular and oral administration. Res Vet Sci, 93(1), 374-377.

16.Shan, Q., Liu, Y. M., He, L. M., Ding, H. Z., Huang, X. H., Yang, F., Li, Y. F. & Zeng, Z. L. (2012) Metabolism of mequindox and its metabolites identification in chickens using lc-ltq-orbitrap mass spectrometry. Journal Of Chromatography B-Analytical Technologies In the Biomedical And Life Sciences, 881-82(15),96-106.

17.Liu, Y. M., Liu, Y. C., Ding, H. Z., Fang, B. H., Yang, F., Shan, Q. & Zeng, Z. L. (2011) Pharmacokinetics of mequindox and its metabolites in swine. Agricultural Sciences In China, 10(12), 1968-1976.

目前主持國家自然基金（青年基金）一項，參與國家自然基金（面上項目）一項。主要研究方向為獸醫藥物代謝動力學（以傳統房室模型和生理葯動學模型為主）、獸醫製劑學、獸葯殘留檢測、獸醫毒理學等。尤其擅長於生理葯動學模型的建立、優化及評價，目前已建立了多種獸葯在不同動物體內的生理葯動學模型用於預測獸葯殘留。