塗曉明
生命科學學院副教授
塗曉明,男,博士,副教授。1976年出生於福建省。1993年至2002年就讀於中國科技大學生命科學學院並先後獲學士,碩士和博士學位。2002年8月至2005年7月在美國加州大學舊金山分校作博士后研究。2005年7月作為中國科技大學優秀人才引進,現為生命科學學院副教授。共發表論文十餘篇。其中,近3年來以第一作者在Molecular Biology of the Cell、Journal of Cell Science、Journal of Biological Chemistry等雜誌發表研究論文6篇(總影響因子超過30)。2006年入選國家教育部“新世紀優秀人才支持計劃”。2005年11月起任安徽省細胞生物學會常務副秘書長。
1、錐體蟲細胞周期調控的分子機制的研究;
2、錐體蟲SUMO系統的研究;
3、Kinesin家族蛋白成員在錐體蟲中的功能研究;
4、錐體蟲作為模式生物用以進行高等真核細胞中核仁的研究。
1:入選國家教育部“2005年新世紀優秀人才支持計劃”;
2:主持承擔國家自然科學基金項目“錐體蟲動點相關蛋白Mad2,Skp1,TOG和中心體相關蛋白Spc97,Spc98在有絲分裂中的功能研究”;
3:主持承擔中國科學院知識創新工程重要方向項目子課題“錐體蟲作為生物模式用以進行高等真核細胞中核仁的研究”。
Xiaoming Tu, Praveen Kumar, Ziyin Li and Ching C. Wang (2006) An aurora kinase homologue is involved in regulating both mitosis and cytokinesis in Trypanosoma brucei. J. Biol Chem. 281:
Ziyin Li*, Xiaoming Tu*, and Ching C. Wang (2006). Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei. Exp. Cell Res. 312:(*contributed equally)
Xiaoming Tu, Joel Mancuso, W. Zacheus Cande and Ching C. Wang (2005) Distinct Cytoskeletal Modulations and Mechanisms Regulating G1/S Transition between Two Life Stages of Trypanosoma brucei Cytoskeletal. Journal of Cell Science. 118:
Xiaoming Tu and Ching C. Wang (2005) Pairwise Knockdowns of cdc2-related Kinases (CRK) in Trypanosoma brucei Identified the CRKs for G1/S and G2/M Transitions and Demonstrated Distinctive Cytokinetic Regulations between Two Developmental Stages of the Organism. Eukaryotic Cell. 4:
Xiaoming Tu and Ching C. Wang (2005) Coupling of Posterior Cytoskeletal Morphogenesis to the G1/S Transition in the Trypanosoma brucei Cell Cycle. Mol. Biol. Cell. 16:97-105.
Xiaoming Tu and Ching C. Wang (2004) The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion. J. Biol. Chem. 279:
Xiaoming Tu, Jihui Wu, Yingqi Xu and Yunyu Shi (2001) Letter to the Editor: 1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain. J. Biomol. NMR. 21:187-188.
Xiaoming Tu, Yazhong Xiao, Wangyong Zeng and Yunyu Shi (2000) Expression and purification of a recombinant DNA-binding domain of ADR6 protein from Escherichia coli and its secondary structure characterization. Biochim. Biophys. Acta. 1481:167-174.
He Zhang, Yuzhi Hong, Yazhong Xiao, Jing Yuan, Xiaoming Tu and Xiaoqing Zhang (2006) Efficient production of laccases by Trametes sp. AH28-2 in cocultivation with a Trichoderma strain. Applied Microbiology and Biotechnology. 73:89-94.
Yazhong Xiao, Xiaoming Tu, J. Wang, M. Zhang, Quan Cheng, Wangyong Zeng, Yunyu Shi (2003) Purification, molecular characterization and reactivity with aromatic compounds of a laccase from basidiomycete Trametes sp. strain AH28-2. Appl. Microbiol. Biotechnol. 60:700-707.
Wangyong Zeng, Xuecheng Zhang, Xiaoming Tu, Shouhong Guang, Yazhong Xiao and Yunyu Shi (2001) Expression and Purification of the DNA-Binding Domain of the Human Transcription Factor E2F1. Protein Expr. and Purif. 21:99-104.