沈偉

上海科技大學助理教授

沈偉博士於2007年本科畢業於清華大學生物科學與技術系;2013年博士畢業於約翰霍普金斯大學生物化學系,其間利用果蠅作為模式生物展開對溫度受體和機制的研究;2013至2014工作於洛克菲勒大學分子遺傳學系,其間利用小鼠作為模式生物展開對溫度調控機制以及肥胖發生機制的研究;2014年7月加盟上海科技大學生命科學與技術學院任助理教授。

研究方向


神經生物學、行為生物學

代表論文


Zhang, Y., Raghuwanshi, R.P., Shen, W.L., and Montell, C. (2013). Food experience-induced taste desensitization modulated by the Drosophila TRPL channel. Nat Neurosci, 16, 1468-1476.
Shen, W.L., Kwon, Y., Adegbola, A.A., Luo, J., Chess, A., and Montell, C. (2011). Function of rhodopsin in temperature discrimination in Drosophila. Science 331, 1333-1336.
Kwon, Y.*, Shen, W.L.*, Shim, H.S., and Montell, C. (2010). Fine thermotactic discrimination between the optimal and slightly cooler temperatures via a TRPV channel in chordotonal neurons. J Neurosci 30, 10465-10471. (* equally contributed)
Xue, X., Yu, H., Yang, H., Xue, F., Wu, Z., Shen, W., Li, J., Zhou, Z., Ding, Y., Zhao, Q., et al. (2008). Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J Virol 82, 2515-2527.
Xue, X., Yang, H., Shen, W., Zhao, Q., Li, J., Yang, K., Chen, C., Jin, Y., Bartlam, M., and Rao, Z. (2007). Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction. J Mol Biol 366, 965-975.
Li, J.*, Shen, W.*, Liao, M., and Bartlam, M. (2007). Preliminary crystallographic analysis of avian infectious bronchitis virus main protease. Acta crystallographica Section F, Structural biology and crystallization communications 63, 24-26. (* equally contributed)