李鵬飛

南方科技大學助理教授

李鵬飛教授,於青島大學獲得化學工程與工藝學士學位,后在大連理工大學精細化工國家重點實驗室攻讀應用化學方向獲得碩士學位,在中國科學院大連化學物理研究所獲得有機化學博士學位。2009.07 – 2011.07 香港理工大學應用生物及化學科技學系,擔任研究助理職位,師從陳滋新(Albert S C Chan )院士,2011年7月至 2012年12月在香港浸會大學創意研究院擔任陳滋新院士的博士后研究員。2012年至今擔任南方科技大學的助理教授。

教育背景


• 2006.09 – 2009.07中國科學院大連化學物理研究所,有機化學,博士
導師:梁鑫淼 研究員
2003.09 – 2006.07大連理工大學精細化工國家重點實驗室,應用化學,碩士
導師:李宗石 教授
1999.09 – 2003.07 青島大學,化學工程與工藝,學士

工作背景


• 2012.01 – 今 南方科技大學化學系,助理教授
2011.07 – 2012.12 香港浸會大學創意研究院,博士后研究員
導師:Albert S C Chan (陳新滋院士)
2009.07 – 2011.07 香港理工大學應用生物及化學科技學系,研究助理
導師:Albert S C Chan (陳新滋 院士)

研究領域


• 新型有機催化劑的設計、合成、應用
• 醫藥中間體的合成
• 化學生物學: 識別及催化

個人專利


• 1. 李鵬飛, 陶紅旗, 段金電. 一種高效合成多取代環己烯酮的製備方法. 專利申請號:201410065763.4 申請日:2014.02.25. 申請公布號:CN103804107A申請公布日:2014.05.21
• 2. 梁鑫淼, 李鵬飛, 葉金星, 王永燦. 一種含有伯胺、叔胺和脲或硫脲的有機催化劑及其製備. 專利申請號:200810011654.9 申請日:2008.06.04. 授權公告號:CN101597286B 授權公告日:2013.04.03 (第一作者為導師)
• Pengfei Li, Jun Wang, Fuk Yee Kwong*. Asymmetric Michael Addition and Related Reactions Stereoselective Synthesis of Drugs and Natural Products (Vasyl Andrushko, Natalia Andrushko. ISBN: 978-1-118-03217-6). Invited book chapter by John Wiley & Sons, 2013.

代表文章


• 12. Pengfei Li, Sau Hing Chan, Albert S C Chan*, Fuk Yee Kwong*. Organocatalytic asymmetric Michael-type reaction between β,γ-unsaturated α-keto ester and α-nitro ketone. Organic & Biomolecular Chemistry, 2011, 9, 7997-7999.
11. Pengfei Li, Sau Hing Chan, Albert S C Chan*, Fuk Yee Kwong*. Organocatalytic Asymmetric Aldol Reaction of Ketones with β, γ-Unsaturated-α-Keto Ester: an Efficient Access to Chiral Tertiary Alcohol Skeletons. Advanced Synthesis & Catalysis, 2011, 353, 1179-1184.
10. Pengfei Li, Junling Zhao, Fengbo Li, Albert S C Chan*, Fuk Yee Kwong*. Highly Enantioselective and Efficient Organocatalytic Aldol Reaction of Acetone and β, γ-Unsaturated-α-Keto Ester. Organic Letters, 2010, 12, 5616-5619.
9. Pengfei Li, Shigang Wen, Feng Yu, Qiaoxia Liu, Wenjun Li, Yongcan Wang, Xinmiao Liang* and Jinxing Ye*. Enantioselective organocatalytic Michael addition of malonates to α, β-unsaturated ketones. Organic Letters, 2009, 11, 753-756.
8. Pengfei Li, Yongcan Wang, Xinmiao Liang* and Jinxing Ye*. Asymmetric multifunctional organocatalytic Michael addition of nitroalkanes to α, β-unsaturated ketones. Chemical Communications, 2008, 3302-3304.
• 26. Jindian Duan, Jing Cheng, Pengfei Li*. Enantioselective construction of spiro-1,3-indandiones with three stereocenters via organocatalytic Michael-aldol reaction of 2-arylideneindane-1,3-diones and nitro aldehydes. Organic Chemistry Frontiers 2015, 2,1048-1052.
25. Jindian Duan, Jing Cheng, Pengfei Li*. DBU Catalyzed One-pot Multicomponent Reaction for the Synthesis of Spirocyclic Tetrahydrothiophene Derivatives. Current Organocatalysis 2015, DOI: 10.2174/2213337202666150414201456.
24. Fang Fang, Genghong Hua, Feng Shi*, Pengfei Li*. Organocatalytic enantioselective Friedel-Crafts reaction: an efficient access to chiral isoindolo-β-carboline derivatives. Organic & Biomolecular Chemistry, 2015, 13, 4356-4356. Inside Front Cover
23. Hongqi Tao (陶紅旗), Jindian Duan (段金電), Qijie He (何其捷), Jun Wang (汪君)*, Pengfei Li (李鵬飛)*. 有機催化靛紅與4-苯基-3-丁炔-2-酮高效合成3-取代-3-羥基氧化吲哚類衍生物. Scientia Sinica Chimica (中國科學:化學), 2015, 45(4), 391-395.
22. Lu Yu, Qingjing Yang, Pengfei Li*. Phase-transfer-catalyst-mediated domino reaction of γ-nitro ketones with chalcones: approach to functionalized six-membered-ring carbocycles. European Journal of Organic Chemistry, 2014, 7499-7504.
21. Lu Yu, Pengfei Li*. New simple primary amine-thiourea organocatalysts and their application in asymmetric conjugate addition. Tetrahedron Letters, 2014, 55, 3697-3700.
20. Hongqi Tao, Jindian Duan, Pengfei Li*. Inorganic-base-catalysed synthesis of α, β- unsaturated ketones and 3,5-disubstituted cyclohex-2-en-1-ones. Asian Journal of Organic Chemistry, 2014, 3, 644-648.
19. Xin Yang, Jun Wang*, Pengfei Li*. Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons. Organic & Biomolecular Chemistry, 2014, 12, 2499-2513. Front Cover.
18. Pengfei Li*, Fang Fang, Ji Chen, Jun Wang*. Organocatalytic asymmetric aza-Michael addition of pyrazole to chalcone. Tetrahedron: Asymmetry, 2014, 25, 98-101.
17. Jindian Duan, Pengfei Li*. Asymmetric organocatalysis mediated by primary amines derived from cinchona alkaloids: recent advances. Catalysis Science & Technology, 2014, 4, 311-320.
16. Yinuo Wu, Fuk Yee Kwong, Pengfei Li*, Albert S C Chan*. An efficient oxidative cross-coupling reaction between C-H and N-H bonds; a transition-Metal-Free protocol at room temperature. Synlett, 2013, 24, 2009-2013.
15. Jun Wang, Pengfei Li*, Pui Ying Choy, Albert S C Chan*, Fuk Yee Kwong*. Recent advances and applications in organocatalytic asymmetric aza-Michael addition. ChemCatChem, 2012, 4, 917-925. Invited review, Back Cover.
14. Jun Wang, Pengfei Li,* Sau Hing Chan, Albert S. C. Chan, Fuk Yee Kwong*. Catalyst-free aza-Michael addition of azole to β,γ-unsaturated-α-keto ester: an efficient access to C-N bond formation. Tetrahedron Letters, 2012, 53, 2887-2889.
13. Yinuo Wu, Jun Wang, Pengfei Li,* Fuk Yee Kwong*. Catalyst-free efficient aza-Michael addition of azoles to nitroalkenes. Synlett, 2012, 23, 788-790