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韓偉

中國科學技術大學教授

韓偉,男,1980年2月出生,博士,中國科學技術大學教授,中國科學院醫學物理與技術中心研究員,中科院百人計劃,主要從事電離輻射生物學效應及電離輻射危害防護。

中國科學院“百人計劃”(海外人才),博士生導師,醫學物理中心輻射生物醫學研究室主任;中國生物物理學會輻射與環境專業青年委員會副主任委員。

2010年11月—至今:中國科學院合肥物質科學研究院醫學物理與技術中心,創新崗位研究員。

教育經歷


大學開始受教育經歷
1996年9月—2000年7月:安徽大學生命科學院學習,生物化學專業,獲學士學位;
2001年9月—2006年6月:中國科學院等離子體物理研究所碩博連讀,等
離子體物理專業(研究方向:輻射生物學),獲博士學位,導師吳李君。

工作經歷


研究情況
2006年9月—2007年4月:香港城市大學物理與材料科學系核輻射研究所 (Nuclear Radiation Unit, Department of Physics and Material Science, City University of Hong Kong), 輻射生物學方向,研究員(research fellow);
2007年5月—2008年5月:哈佛大學醫學院麻省總醫院放射腫瘤系(Department of Radiation Oncology, Massachusetts General Hospital/Harvard Medical School), 輻射生物學方向,博士后研究員(post-doctoral research fellow);
2008年7月—2010年11月:香港城市大學物理與材料科學系核輻射研究所 (Nuclear Radiation Unit, Department of Physics and Material Science, City University of Hong Kong), 輻射生物學方向,高級研究副職 (senior research associate);
2010年11月—至今:中國科學院合肥物質科學研究院醫學物理與技術中心(籌),輻射醫學生物學方向,研究員,入選中國科學院“百人計劃”候選人名單;
2011年5月—至今:獲聘中國科學院研究生院博士生導師;
2011年8月—至今:獲得中國科學院“百人計劃”擇優支持;
2011年9月—至今:獲聘中國科學技術大學教授。

個人作品


已發表文章與著作:
1.Jie Ma, Hao Zhang, Cheng Cheng, Jie Shen, Lingzhi Bao, Wei Han*. Contribution of hydrogen peroxide to non-thermal atmospheric pressure plasma induced A549 lung cancer cell damage, Plasma Processes and Polymers, 2016, DOI 10.1002/ppap.201600162.
2.Wenqing Wu, Lili Nie, K. N. Yu, Lijun Wu, Peizhong Kong, Lingzhi Bao, Guodong Chen, Haoran Yang and Wei Han*. Low Concentration of Exogenous Carbon Monoxide Modulates Radiation-Induced Bystander Effect in Mammalian Cell Cluster Model, International Journal of Molecular Science, 17, 2051, 2016.
3.Lingzhi Bao, Jie Ma, Guodong Chen, Jue Hou, Tom K. Hei, K.N. Yu, Wei Han*.Role of heme oxygenase-1 in low dose radioadaptive response, Redox Biology, 8, 333-340, 2016.
4.Wei Li,K.N. Yu,Lingzhi Bao, Jie Shen, Cheng Cheng, Wei Han*. Non-thermal plasma inhibits migration and invasion of human cervical cancer HeLa cells. Scientific Reports, 6, 19720, 2016.
5.HongzhiWang, K.N.Yu, JueHou, QianLiu, Wei Han*. Radiation-induced bystander effect: Early process and rapid assessment, Cancer Letters, 356(1): 137-144, 2015. (邀請綜述)
6.Jue Hou,Jie Ma,K. N. Yu,Wei Li,Cheng Cheng,Lingzhi Bao, Wei Han*,Non-thermal plasma treatment altered gene expression profiling in non-small-cell lung cancer A549 cells, BMC Genomics,16:435, 2015.
7.Jue Hou, Fan Wang, Peizhong Kong,K.N. Yu,Hongzhi Wang, Wei Han*, Gene profiling characteristics of radioadaptive response in AG01522 normal human fibroblasts. PLoS ONE 10, e0123316. doi:10.1371/journal.pone.0123316, 2015.
8.Liping Tong, K.N. Yu,Lingzhi Bao, Wenqing Wu, Hongzhi Wang, Wei Han*. Low concentration of exogenous carbon monoxide protects mammalian cells against proliferation induced by radiation-induced bystander effect, Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 759(1): 9-15, 2014.
9.Wei Han, K.N. Yu, Lijun Wu, Yican Wu and Hongzhi Wang, Mechanism of protection of bystander cells by exogenous carbon monoxide: impaired response to damage signal of radiation-induced bystander effect, Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2011, 709-710, 1-6.
10.Wei Han, Lijun Wu, Shaopeng Chen and K.N. Yu, Exogenous carbon monoxide protects the bystander Chinese hamster ovary cells in mixed co-culture system after alpha-particle irradiation, Carcinogenesis, 2010, 31, 275-280.
11.Wei Han, Shaopeng Chen, K.N. Yu and Lijun Wu, Nitric oxide mediated DNA double strand breaks induced in proliferating bystander cells after alpha-particle irradiation, Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2010, 684, 81-89.
12.Wei Han, Lijun Wu, ShaopengChen, LinzhiBao, LeileiZhang, ErkangJiang, YeZhao, AnXu, Tom K.Hei and ZengliangYu, Constitutive nitric oxide acting as a possible intercellular signaling molecule in the initiation of radiation-induced DNA double strand breaks in non-irradiated bystander cells, Oncogene, 2007, 26,2330-2339.
13.Wei Han, Lijun Wu , Burong Hu, Leilei Zhang, Shaopeng Chen, Lingzhi Bao, An Xu and Zengliang Yu, The early and initiation process of radiation-induced bystander effects involving in the induction of DNA double strand breaks in non-irradiated cultures, British Journal of Radiology, 2007, 80, S7-S12. (邀請文章)
14.Wei Han, Lingyan Zhu, Erkang Jiang, Jun Wang, Shaopeng Chen, Linzhi Bao, Ye Zhao, An Xu, Zengliang Yu, Lijun Wu, Elevated sodium chloride concentrations enhance the bystander effects induced by low dose alpha-particle irradiation. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2007, 624, 124-131.
15.Burong Hu#, Wei Han#, Lijun Wu, Huiyun Feng, Xuelan Liu, Leilei Zhang, An Xu, Tom K. Hei and Zengliang Yu, In situ visualization of DSBs to assess the extranuclear/extracellular effects induced by low dose α-particle irradiation, Radiation Research, 2005, 164,286-291. (#:共同第一作者)
Book Chapters:
16.Wei Han, Peter K.N. Yu, Low Dose Radiation, DNA Double Strand Break and Mutation, Chapter 7 in Mutations: Types, Harmful Mutations and Beneficial Mutations, Nova Science Publishers, Inc. New York. 2010.
17.Wei Han, Peter K.N. Yu, Response of cells to ionizing radiation, Chapter 6 in Advances in Biomedical Science and Engineering, edited by S C Tjong, Bentham Science Publishes Ltd. Illinois. 204-262, 2009.
在研課題:
2011.01-2013.12 國家自然科學基金(青年項目)外源性一氧化碳對輻射旁效應信號傳導的調節作用及機理研究(31000384)8月—至今:獲得中國科學院“百人計劃”擇優支持;
2012.01-2015.12 國家自然科學基金(面上項目)輻射誘發三維尺度旁效應信號傳遞與一氧化碳的調控關係(81172602)
2011.08-2014.08 中國科學院(“百人計劃”擇優項目)輻射生物體作用的信號傳導與調控