李銳

2008年畢業於武漢大學生命科學院生物學基地班，獲理學學士學位；2013年畢業於美國田納西大學營養系，獲博士學位；2013年7月加入武漢大學公共衛生學院營養與食品衛生系。

主要研究課題：1. 維生素A對肝臟葡萄糖和脂質代謝的影響

2. 進食頻率和進食時間對動物體重的影響。

代表性論著：

1. Li, R., Zhang, R., Li, Y., Zhu, B., Chen, W., Zhang, Y., Chen, G. (2014). An RARE of Hepatic Gck Promoter Interacts with RARα , HNF4α , and COUP-TFII that Affect Retinoic Acid- and Insulin-induced Gck expression. J Nutr Biochem. 25 (9): 964-976.

2. Howell, M., Li, R., Zhang, R., Li, Y., Chen, W., Chen, G. (2013). The expression of Apoc3 mRNA is regulated by HNF4α and COUP-TFII, but not acute retinoid treatments, in primary rat hepatocytes and hepatoma cells. Mol Cell Biochem. 387 (1-2): 241-250.

3. Li, Y., Zhang, Y., Li, R., Chen, W., Howell, M., Zhang, R., and Chen, G. (2012). The Hepatic Raldh1 Expression Is elevated in Zucker Fatty Rats and Its Over-Expression Introduced the Retinal-Induced Srebp-1c Expression in INS-1 Cells. PLoS One 7, e45210.

4. Liu, L., Cao, Z., Chen, J., Li, R., Cao, Y., Zhu, C., Wu, K., Wu, J., Liu, F., and Zhu, Y. (2012). Influenza A Virus Induces Interleukin-27 through Cyclooxygenase-2 and Protein Kinase A Signaling. Journal of Biological Chemistry 287, 11899-11910.

5. Zhao, S., Li, R., Li, Y., Chen, W., Zhang, Y., and Chen, G. (2012). Roles of vitamin A status and retinoids in glucose and fatty acid metabolism. Biochem Cell Biol. 90 (2): 142-152.

6. Zhang, Y., Chen, W., Li, R., Li, Y., Ge, Y., and Chen, G. (2011). Insulin-regulated Srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditions. PLoS One 6, e21342.

7. Ge, Y., Zhang, Y., Li, R., Chen, W., Li, Y., and Chen, G. (2011). Berberine regulated Gck, G6pc, Pck1 and Srebp-1c expression and activated AMP-activated protein kinase in primary rat hepatocytes. Int J Biol Sci 7, 673-684.

8. Zhang, Y., Li, R., Chen, W., Li, Y., and Chen, G. (2011). Retinoids induced Pck1 expression and attenuated insulin-mediated suppression of its expression via activation of retinoic acid receptor in primary rat hepatocytes. Mol Cell Biochem 355, 1-8.

9. Li, R., Chen, W., Li, Y., Zhang, Y., and Chen, G. (2011). Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action. Biochem Biophys Res Commun 406, 268-272.

10. Liu, L., Li, R., Pan, Y., Chen, J., Li, Y., Wu, J., and Zhu, Y. (2011). High-throughput screen of protein expression levels induced by cyclooxygenase-2 during influenza a virus infection. Clin Chim Acta 412, 1081-1085.