高雲華

1989年7月赴日本朝日大學從事訪問研究，1990年轉入日本岡山大學攻讀學位，1996年3月獲得博士學位。

1998年至2000年底在日本岡山大學自然科學研究科VBL(Venture Business Lab)任講師。

2000年入選中國科學院“百人計劃”

2001年回國工作現任中國科學院理化技術研究所研究員，博士生導師。

研究領域

主要研究方向是生物晶元/生物感測器高靈敏高通量快速檢測技術平台的研究以及新型經皮給葯系統的研究。

在研項目： 1) “863”計劃先進位造技術領域：“新型CMOS生物感測器集成技術研究”

2) 科技部支撐計劃課題“出入境檢驗檢疫安全儲備技術研究”

3) 中科院創新方向性項目：“抗腫瘤納米藥物微針透皮釋葯研究”

4) 中科院儀器設備研製和改造項目：“BioMEMS基片快速成型系統的研製”企業合作項目3項

論文

1) Microneedle Array for Transdermal Drug Delivery: Studies on Delivery Parameters and Biocompatibility，Yan Wu, Suohui Zhang, Yuqin Qiu, Guangjiong Qin and Yunhua Gao1*, Biomedical microdevices (in press).

2) Enhancement of skin permeation of docetaxel by a combination of microneedle pretreatment and elastic liposomes，Yuqin Qiu, Yunhua Gao1*, Kejia Hu, Fang Li , J. controlled release,(in press).

3）Synthesis, characterization and photochromic studies of three novel calix[4]arene–Schiff bases, Zhi Liang , Zhilian Liu , Yunhua Gao,* Spectrochimica Acta Part A

4) A new fluorescent chemosensor for copper(II) and molecular switch controlled by light, Zhi Liang, Zhilian Liu, Lin Jiang and Yunhua Gao,*Tetrahedron Letters

5) A selective colorimetric chemosensor based on calixarene framework for lanthanide ions-Dy3+ and Er3+, Zhi Liang, Zhilian Liu and Yunhua Gao,* Tetrahedron Letters

6) Functionalization of chitosan with 3,4-dihydroxybenzoic acid for the adsorption/collection of uranium in water samples and its determination by inductively coupled plasma-mass spectrometry，Akhmad Sabarudin, Mitsuko Oshima, Toshio Takayanagi, Lukman Hakim, Koji Oshita, Yun Hua Gao and Shoji Motomizu, Analytica Chimica Acta

7）Sequential-injection on-line preconcentration using chitosan resin functionalized with 2-amino-5-hydroxy benzoic acid for the determination of trace elements in environmental water samples by inductively coupled plasma-atomic emission spectrometry, Akhmad Sabarudin , Narong Lenghor , Mitsuko Oshima, Lukman Hakim, Toshio Takayanagi , Yun-Hua Gaob, Shoji Motomizua* Talanta

8） A selective colorimetric chemosensor for lanthanide ions, Zh. Liu, L. Jiang, Zh. Liang and Y. Gao*, Tetrahedron

9） Modeling of transdermal drug delivery with a microneedle array, Y-G Lv, J Liu, Y-H Gao and B Xu, J. Micromech. Microeng

10) Photochromism of a novel spiropyran derivative based on calix[4]arenas, Zhilian Liu, Lin Jiang, Zhi Liang, Yunhua Gao*, J. Mol. Struct,

11) Magnetically-Actuated Micromixing on Array-Pattern Microfluidic Chip for Immunoassay of TSH，Chengwu Li, Yongning Wang, Yunhua Gao*, XiaoYing Guo and Zhongze Gu， Journal of Nanoscience and Nanotechnology

12) An Artificial Aspartic Proteinase System, Lin Jiang, Zhilian Liu, Zhi Liang, and Yunhua Gao*, Bioorganic & Medicinal Chemistry

13) Photo-switching molecular devices based on metal-ionic recognition, Zhilian Liu, Lin Jiang , Zhi Liang and Yunhua Gao*, Tetrahedron Letters

14) Controlled transdermal delivery of model drug compounds by MEMS microneedle array，Yu Xie1, Bai Xu2*, Yunhua Gao1*, Nanomedicine