王淑芳

南開大學教授

王淑芳,從事生物材料的結構與功能關係及其應用研究。主持或參加國家級、省部級科研項目二十餘項。研究方向:生物醫藥用高分子材料。

人物經歷


1963年出生,理學博士,教授,博士生導師;畢業於南開大學化學學院高分子化學與物理專業;現就職於南開大學生命科學學院生物活性材料教育部重點實驗室。

研究方向


生物功能高分子材料的結構與性能關係及其應用研究(包括血管組織工程支架材料構建,新型生物降解高分子材料的藥物控釋及載葯新技術研究)。

主要貢獻


主持國家自然科學基金項目——自催化NO原位控釋的人工血管植入材料結構設計及其生物功能評價(51073081,2011.1-2013.12);主持天津市基礎研究重點項目——用於組織工程的中長鏈聚羥基脂肪酸酯PHAMCL的研究(09JCZDJC18400,2009.1-2011.12);參加天津市科技支撐重點項目——微生物法合成聚谷氨酸的產業化中試及其應用研究(09ZCKFSH00800,2009.1-2011.12);參加國家自然科學基金重點項目——小口徑血管材料結構設計與組織再生(50830104,2009-2012);參加國家自然科學基金項目——門多薩假單胞菌NK-01合成褐藻寡糖和中長鏈聚羥基脂肪酸酯的代謝途經改造(31070039,2011.1-2013.12)等。
在Biomacromolecules,Polymer Degradation and Stability, Journal of Polymers and the Environment, Polymers for Advanced Technologies, Journal of Molecular Structure, Polymer Testing, Journal of Molecular Catalysis B: Enzymatic等國內外學術期刊發表學術論文四十餘篇,多篇被SCI或EI收錄;申請中國發明專利三十餘項,其中多項授予專利權。
論文論著
1.Zheng WT, Wang ZH, Song LJ, Zhao Q*, Zhang J, Li D, Wang SF, Zheng XL, Han JH, Yang ZM, Kong DL*. Endothelialization and patency of RGD-functionalized vascular grafts in a rabbit carotid artery mode. Biomaterials 33-10-2880-2891. 2012-4-1
近期發表的論文
(1)Qiang Zhao, Shufang Wang*, Meimei Kong, Weitao Geng, Robert K. Y. Li, Cunjiang Song*, Deling Kong. Phase morphology, physical properties, and biodegradation behavior of novel PLA/PHBHHx blends. Journal of Biomedical Materials Research B: Applied Biomaterials. 2012, 100B (1): 23-31.
(2)Wenbin Guo, Cunjiang Song, Meimei Kong, Weitao Geng, Yuanyuan Wang, Shufang Wang*. Simultaneous production and characterization of medium-chain-length polyhydroxyalkanoates and alginate oligosaccharides by Pseudomonas mendocina NK-01. Applied Microbiology and Biotechnology. 2011, 92, 791-801
(3)Congxin Li, Tianying Guo, Dezhong Zhou, Yuling Hu, Hao Zhou, Shufang Wang, Jiatong Chen, Zhengpu Zhang. A novel glutathione modified chitosan conjugate for efficient gene delivery. Journal of Controlled Release 2011, 154, 177–188.
(4)Qiang Zhao, Shufang Wang, Xinjian Cheng, Richard CM. Yam, Deling Kong*, Robert KY Li, Surface Modification of Cellulose Fiber via Supramolecular Assembly of Biodegradable Polyesters by the aid of Host-Guest Inclusion Complexation. Biomacromolecules, 2010, 11(5), 1364-1369.
(5)Wenbin Guo, Jian Tao, Chao Yang, Qiang Zhao, Cunjiang Song, Shufang Wang*, The rapid evaluation of material biodegradability using an improved ISO 14852 method with a microbial community, Polymer Testing, 2010, 29, 832-839.
(6)Mingfeng Cao , Cunjiang Song, Yinghong Jin, Li Liu , Jing Liu, Hui Xie, Wenbin Guo, Shufang Wang* Synthesis of Poly (γ-glutamic acid) and Heterologous Expression of pgsBCA Genes,Journal of Molecular Catalysis B: Enzymatic, 2010, 67, 111-116.
(7)Mingfeng Cao, Weitao Geng, Li Liu, Congjiang Song, Hui Xie, Wenbin Guo, Yinghong Jin, Shufang Wang*. Glutamic acid independent production of poly(γ-glutamic acid) by Bacillus amyloliquefaciens LL3 and cloning of pgsBCA genes. Bioresource technology,2011, 102, 4251-4257
(8)Lei Zhang, Kai Wang, Qiang Zhao, Wenting Zheng, Zhihong Wang, Shufang Wang*, Deling Kong*. Core-shell fibrous vascular graft with nitric oxide releasing property, Science in China Series B: Chemistry, 2010, 53(3): 528-534.
(9)Min Zhang, Zhexiang Wang, Zefang Wang, Shuren Feng, Haijin Xu, Qiang Zhao, Shufang Wang, Jianxin Fang, Mingqiang Qiao?, Deling Kong?. Immobilization of anti-CD31 antibody on electrospun poly(ε-caprolactone) scaffolds through hydrophobins for specific adhesion of endothelial cells. Colloids Surf B Biointerfaces. 2011, 85 (1): 32-39.
(10)Zhihong Wang, Huaimin Wang, Wenting Zheng, Jun Zhang , Qiang Zhao , Shufang Wang , ZhimouYang , Deling Kong. Highly stable surface modifications of poly(ε-caprolactone) (PCL) films by molecular self-assembly to promote cells adhesion and proliferation. Chem Commun 2011, 47: 8901-8903.
(11)Qian Li, Zhihong Wang, Qiang Zhao, Lianyong Wang, Shufang Wang , Deling Kong. Synthesis and characterization of a zwitterionic copolymer poly(ε--caprolactone)-b-poly(carboxybetaine methacrylate) with good cell affinity. Chinese J Biomed Eng 2011, 20: 47-54.
(12)Jian Tao; Cunjiang Song; Cao Mingfeng; Dan Hu; Li Liu; Na Liu; Shufang Wang*. Thermal Properties and Degradability of Poly (propylene carbonate) / Poly (β-hydroxybutyrate-co-β-hydroxyvalerate) (PPC / PHBV) Blends. Polymer Degradation and Stability, 2009, 94(4):573-583.

獲獎記錄


獲得了國家科技進步三等獎、中國專利優秀獎、天津市專利優秀獎、天津市自然科學二等獎、天津市技術發明二等獎(兩項)和天津市科技進步二等獎,還獲得南開大學優秀教育工作者等稱號。