黃曼

黃曼臨床危重病醫學專家

黃曼,女,主任醫師,博士生導師

浙江大學醫學院附屬第二醫院綜合ICU主任

《中華急診醫學雜誌》編委

中國研究型醫院學會危重症醫學專業委員會 常委

中國老年學會急診分會 常委

中國醫師協會體外生命支持協會 委員

中國研究型醫院學會休克膿毒症分會 委員

中國醫促會急診急救分會委中華醫學會急診醫學危重症學組 委員

中國老年學會重症分會 委員

浙江省重症醫學分會 委員

浙江省神經科學學會 理事

浙江省醫學會營養與代謝分會重症營養學組副組長

研究方向


基礎研究聚焦細胞因子在膿毒症免疫功能障礙中的機制研究、膿毒症腦病、膿毒症腎病的發病機制研究;臨床關注重症感染、重症神經、重症腎臟的診治及治療,重症複雜血液凈化治療及ECMO在重症領域應用有豐富的臨床經驗。

教育經歷


1994年獲臨床醫學學士學位,2003年獲神經病學碩士學位,2013年獲神經病學博士學位

工作經歷


2005.9-2014.7浙江大學醫學院附屬邵逸夫醫院重症醫學科副主任醫師
2014.8-浙江大學醫學院附屬第二醫院 綜合ICU

科研成果


國家自然基金面上項目:81873946,IL-36通過自噬調控膿毒癥狀態下調節性T細胞免疫功能的作用及其機制
國家自然基金面上項目:81271200-α-倒捻子素及其衍生物在治療阿爾茨海默氏病中的化學生物學研究,
浙江省科技廳公益技術研究發展項目:2011C23080-CRRT對腹腔高壓病人的腸功能障礙的影響。
浙江省衛生廳A類項目:2009A117-急性腦出血患者血液中微粒的檢測及臨床意義。
國家自然科學基金:No. 81100249-rhEPO對肝外梗阻性黃疸腸粘膜屏障功能的影響及機制的研究。
1.
國家自然基金面上項目:81873946,IL-36通過自噬調控膿毒癥狀態下調節性T細胞免疫功能的作用及其機制
2.
國家自然基金面上項目:81271200-α-倒捻子素及其衍生物在治療阿爾茨海默氏病中的化學生物學研究,
3.
浙江省科技廳公益技術研究發展項目:2011C23080-CRRT對腹腔高壓病人的腸功能障礙的影響。
4.
浙江省衛生廳A類項目:2009A117-急性腦出血患者血液中微粒的檢測及臨床意義。
5.
國家自然科學基金:No. 81100249-rhEPO對肝外梗阻性黃疸腸粘膜屏障功能的影響及機制的研究。

論文著作


Kongmiao Lu, MD, Fei Zeng, BD, Yi Li, BD, Cheng Chen, BD, Man Huang, PhD∗A more physiological feeding process in ICU Intermittent infusion with semi-solid nutrients (CONSORT-compliant)
Medicine (2018) 97:36(e12173)

Yun Ge, Zhijun Xu, Yanting Hu, Man Huang*
Successful voriconazole treatment of Talaromyces marneffei infection in an HIV-negative patient with osteolytic lesions ,J Infect Chemother xxx (2018) 1e4
Ting-Ting Geng, MM, Xin Xu, MM, Man Huang, MD∗High-dose tigecycline for the treatment of nosocomial carbapenem-resistant Klebsiella pneumoniae bloodstreaminfections A retrospective cohort study ,Medicine (2018) 97:8
Man Huang2*, Zhi-Lan Chen1*, Jun Fu3, Xia-Rong Wang1, Jian-Qing Gao1, Zheng Xia4,Pegylated or non-pegylated liposomal doxorubicin in the management of advanced breast cancer: a meta-analysis,Int J Clin Exp Med 2016;9(2):525-534IF1.6
Zhi-Lan Chen, BSa,1, Man Huang, MDb,1, Xia-Rong Wang, BSa, Jun Fu, MDc, Min Han, PhDa, You-Qing Shen, PhDd, Zheng Xia, MDe,⁎, Jian-Qing Gao, PhDa,Transferrin-modified liposome promotes α-mangostin to penetrate the blood–brain barrier Nanomedicine: Nanotechnology, Biology, and Medicine ,2016;1
Huang Man, Lack of Genetic Association Between TREM2 and Alzheimer's Disease in East Asian Population: A Systematic Review and Meta-Analysis,American Journal of Alzheimer’s Disease & Other Dementias® 2015, Vol. 30(6) 541-546
9( IF1.518)
Huang, Man,γ-Secretase inhibitor DAPT prevents neuronal death and memory impairment in sepsis associated encephalopathy in septic rats ,Chin Med J 2014;127 (5): 924-928(IF1.4)
8.Huang, Man, High concentrations of procoagulant microparticles in the cerebrospinal fluid and peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome Surgical Neurology, 72(5), pp 481-489, 2009/11.(IF2.8)
9.Huang, Man; *Hu, Yue-Yu; Dong, Xiao-Qiao; Xu, Qiu-Ping; Yu, Wen-Hua; Zhang, Zu-YongThe protective role of oxymatrine on neuronal cell apoptosis in the hemorrhagic rat brainJOURNAL OF ETHNOPHARMACOLOGY, 143(1), pp 228-235, 2012/8/30.,IF3.01
Hu, Yue-Yu,*Huang, Man, Dong, Xiao-Qiao, Xu, Qiu-Ping, Yu, Wen-Hua, Zhang, Zu-Yong Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: Possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway Journal of Ethnopharmacology, 137(3), pp 1462-1468, 2011/10/11.IF2.466(通訊作者)
*Dong, Xiao-Qiao,Huang, Man, Yang, Song-Bin, Yu, Wen-Hua, Zhang, Zu-Yong Copeptin Is Associated With Mortality in Patients With Traumatic Brain Injury Journal of Trauma-Injury Infection and Critical Care, 71(5), pp 1194-1198, 2011/11.IF1.13
*Dong, X. -Q.,Huang, M., Hu, Y. -Y., Yu, W. -H., Zhang, Z. -Y. Time course of plasma microparticle concentrations after acute spontaneous basal ganglia hemorrhage Acta Neurologica Scandinavica, 123(4), pp 280-288, 2011/4.IF2.55
1.
Kongmiao Lu, MD, Fei Zeng, BD, Yi Li, BD, Cheng Chen, BD, Man Huang, PhD∗A more physiological feeding process in ICU Intermittent infusion with semi-solid nutrients (CONSORT-compliant)
Medicine (2018) 97:36(e12173)

2.
Yun Ge, Zhijun Xu, Yanting Hu, Man Huang*
Successful voriconazole treatment of Talaromyces marneffei infection in an HIV-negative patient with osteolytic lesions ,J Infect Chemother xxx (2018) 1e4
3.
Ting-Ting Geng, MM, Xin Xu, MM, Man Huang, MD∗High-dose tigecycline for the treatment of nosocomial carbapenem-resistant Klebsiella pneumoniae bloodstreaminfections A retrospective cohort study ,Medicine (2018) 97:8
4.
,
5.
Zhi-Lan Chen, BSa,1, Man Huang, MDb,1, Xia-Rong Wang, BSa, Jun Fu, MDc, Min Han, PhDa, You-Qing Shen, PhDd, Zheng Xia, MDe,⁎, Jian-Qing Gao, PhDa,Transferrin-modified liposome promotes α-mangostin to penetrate the blood–brain barrier Nanomedicine: Nanotechnology, Biology, and Medicine ,2016;1
6.
Huang Man, Lack of Genetic Association Between TREM2 and Alzheimer's Disease in East Asian Population: A Systematic Review and Meta-Analysis,American Journal of Alzheimer’s Disease & Other Dementias® 2015, Vol. 30(6) 541-546
9( IF1.518)
7.
IF1.4)
8.
Huang, Man
9.
Huang, Man
10.
*Huang, Man
11.
Huang, Man
12.
Huang, M.