羅傑

羅傑，男，博士，教授。長期從事植物次生代謝調控及代謝組學研究。2002年博士畢業於華中科技大學植物生物技術專業。2003-2008年在英國著名研究所John Innes Centre從事訪問及博士后研究。

1989-1994:湖北工業大學 食品工程 學士；

1994-1997: 大連輕工業大學 微生物工程 碩士；

1998-2002: 華中科技大學 植物生物技術 博士。

職 歷

1997-2008 華中科技大學生命科學與技術學院，先後任講師，副教授；

2003-2008 英國John Innes Centre,先後從事訪問及博士后研究；

2008-今 華中農業大學生命科學技術學院任教授,博士生導師；

現擔任湖北省生化與分子生物學會常務理事、中國生化與分子生物學會農業分會理事、湖北省遺傳學會理事、植物學報編委、Scientific Data (Nature系列）編委。

代謝物作為植物與環境相互適應的最直接的因素，因其本身種類的繁多和數量的龐大而具有極為豐富的自然變異。代謝組學作為系統生物學的重要分支，是20世紀90年代末期發展起來的一門新興學科，近年來在植物研究領域受到廣泛關注，並取得了一系列重要進展。據估計，地球上存在超過40萬種植物，並且所有植物代謝產物大約有20萬到100萬種，這意味著植物代謝物的應用具有巨大的潛力，特別是天然產物藥物研究，將極大促進各種新葯的開發和應用。

代謝組是基因與表型的橋樑。將基因組和表型組聯繫起來，利用基因組已有的大量數據，結合代謝組和全基因組關聯分析，進行代謝組的全基因組關聯分析可以極大的推動我們對植物代謝組學的研究，增強對代謝組遺傳基礎的了解，這些認知可以促進我們對植物特別是糧食作物進行相應的遺傳改良，以便獲得具有更好抗性、更高產量和品質的優異品種。

該課題組（作物代謝生物學，Crop Metabolic Biology）以水稻、玉米，柑橘等作物為材料，通過代謝組學研究，深化人們對代謝組遺傳基礎的理解，有助於搭建基因組和表型組之間的橋樑，同時對於

利用代謝工程進行營養品質改良具有積極意義。也可以為功能基因組學研究提供一種高效、快速進行大規模基因功能鑒定的新方法，為作物逆境生理及營養品質形成機制研究和遺傳改良實踐提供新資源和新思路。

2009年加入華中農業大學併入選教育部新世紀優秀人才資助計劃，主持國家自然科學基金、“863”重點項目、“973”課題等多項。2016年8月榮獲“國家傑出青年科學基金”資助。在Nature Genetics, Nature Biotechnology, Nature Communications, Plant Cell, PNAS, Current Opinion in Plant Biology, Plant Journal, Molecular Plant, Food Chemistry, Journal of Experimental Botany, Journal of Integrative Plant Biology,生命科學和科技導報等主流期刊發表多篇高水平論文，申請並獲批了國家發明專利多項。該研究為代謝組與功能基因組研究提供了新思路，新方向，並多次應邀在國際國內學術會議上做大會報告任教期間，主講的《分子生物學》深受師生青睞，併入選國家級精品資源共享課程。

論著

1. Chen W, Wang W, Peng M, Gong L, Gao Y, Wan J, Wang S, Shi L, Zhou B, Li Z, Peng X, Yang C, Qu L, Liu X,Luo J*. Comparative and parallel genome-wide association studies for metabolic and agronomic traits in cereals.Nature Communication, 2016, In Press. (SCI, IF: 11.3).

2. Peng M, Gao Y, Chen W, Shen S, Shi J, Wang C, Zhang Y, Zou L, Wang S, Wan J, Liu X,Luo J*. Evolutionarily Distinct BAHD N-acyltransferases are Responsible for Natural Variation of Aromatic Amine Conjugates in Rice.Plant Cell, 2016, Vol.28: 1533–1550. (SCI, IF: 10.0) .

3. Fang C, Zhang H, Wan J, Wu, Y, Li K, Jin C, Chen W, Wang S, Wang W, Zhang H, Zhang P, Zhang F, Qu L, Liu X, Zhou D,Luo J*. Control of Leaf Senescence by a MeOH-Jasmonates Cascade That Is Epigenetically Regulated by OsSRT1 in Rice.Molecular Plant, 2016, In Press. (SCI, IF: 7.1) .

4. Qu L, Wu C, Zhang F, Wu Y, Fang C, Jin C, Liu X,Luo J*. Rice putative methyltransferase gene OsTSD2 is required for root development involving pectin modification.Journal of Experimental Botany, 2016, In Press. (SCI, IF: 5.7) .

5. Jin C, Fang C, Yuan H, Wang S, Wu Y, Liu X, Zhang Y,Luo J*. Interaction between carbon metabolism and phosphate accumulation is revealed by a mutation of a cellulose synthase-like protein, CSLF6.Journal of Experimental Botany, 2015, 66(9):15-15. (SCI, IF: 5.7) .

6. 劉賢青, 董學奎,羅傑. 基於連鎖與關聯分析的植物代謝組學研究進展.生命科學, 2015(8):986-994.

7. 劉賢青,羅傑. 植物代謝組學技術研究進展.科技導報, 2015(16):33-38.

8. Wang S, Tu H, Wan J, Chen W, Liu X,Luo J, Xu J, Zhang H. Spatio-temporal distribution and natural variation of metabolites in citrus fruits.Food Chemistry, 2015, 199:8-17. (SCI, IF: 4.1) .

9.Luo J*. Metabolite-based genome-wide association studies in plants.Current Opinion in Plant Biology, 2015, 24: 31-38. (SCI, IF: 9.4) .

10. Dong X, Gao Y, Chen W, Wang W, Gong L, Liu X,Luo J*. Spatio-temporal distribution of phenolamides and the genetics of natural variation of hydroxycinnamoyl spermidine in rice.Molecular Plant, 2015, 8: 111-121. (SCI, IF: 6.7) .

11. Chen W, Gao Y, Xie W, Gong L, Lu K, Wang W, Li Y, Liu X, Zhang H, Dong H, Zhang W, Zhang L, Yu S, Wang G, Lian X*,Luo J*. Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism.Nature Genetics, 2014, 46: 714-721. (SCI, IF: 31.6) .

12. Dong X, Chen W, Wang W, Zhang H, Liu X,Luo J*. Comprehensive profiling and natural variation of flavonoids in rice.Journal of Integrative Plant Biology, 2014, 56: 876-886. (SCI, IF: 3.7) .

13. Wen W, Li D, Li X, Gao Y, Li W, Li H, Liu J, Liu H, Chen W,Luo J*and Yan J*. Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights.Nature Communication, 2014, 5: 3438-3447. (SCI, IF: 10.2) .

14. Gong L, Chen W, Gao Y, Liu X, Zhang H, Xu C, Yu S, Zhang Q*,Luo J*. Genetic analysis of the metabolome exemplified using a rice population.Proceedings of the National Academy of Sciences of the United States of America, 2013, 110: 20320-20325. (SCI, IF: 9.4) .

15. Chen W, Gong L, Guo Z, Wang W, Zhang H, Liu X, Yu S, Xiong L,Luo J*. A novel integrated method for large-scale detection, identification, and quantification of widely targeted metabolites: application in the study of rice metabolomics.Molecular Plant, 2013, 6: 1769-1780. (SCI, IF: 6.7) .

16.Luo J, Fuell C, Parr A, Hill L, Elliott K, Michael AJ and Martin C.A novel spermidine acyltransferase responsible for the accumulation of polyamine conjugates in Aradidopsis seed.Plant Cell, 2009, 21(1): 318-333. (SCI, IF: 9.653) of both types of polyphenol.Plant Journal, 2008,56(2):316-326. (SCI, IF: 6.751) .

17. Butelli E, Titta L, Giorgio M, Mock HP, Matros A, Peterek S, Schijlen EG, Hall RD, Bovy AG,Luo J, Martin C. Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors.Nature Biotechnology, 2008, 26(11):1301-1308. (SCI, IF: 22.848) of both types of polyphenol.Plant Journal, 2008,56(2):316-326. (SCI, IF: 6.751).

18.Luo J, Butelli E, Hill L, Parr A, Niggeweg R, Bailey P, Weisshaar B, Martin C. AtMYB12 regulates caffeoyl quinic acid and flavonol synthesis in tomato; expression in fruit results in very high levels of both types of polyphenol.Plant Journal, 2008,56(2):316-326. (SCI, IF: 6.751) of both types of polyphenol.Plant Journal, 2008,56(2):316-326. (SCI, IF: 6.751).

19.Luo J, Nishiyama Y, Fuell C, Taguchi Get al.Convergent evolution in the BAHD family of acyl transferases: identification and characterization of anthocyanin acyl transferases fromArabidopsis thaliana.Plant Journal, 2007, 50(4): 678–695. (SCI, IF: 6.751) of both types of polyphenol.Plant Journal, 2008,56(2):316-326. (SCI, IF: 6.751).

20. Chang JL*,Luo J*, He GY. Regulation of accumulation of polyphenols by combined overexpression/silencing key enzymes of phyenylpropanoid pathway.Acta Biochimica et Biophysica Sinica, 2009,41(2): 123-130. (*, equal contribution) (SCI, IF: 1.017) of both types of polyphenol.Plant Journal, 2008,56(2):316-326. (SCI, IF: 6.751).

21. Fang JY, Liu Y,Luo J, Wang YS, Shewry PR, He GY. Allelic variation and genetic diversity of high molecular weight glutenin subunit in Chinese endemic wheats (Triticum aestivumL.).Euphytica, 2009, 166(2): 177-182. (SCI, IF: 1.05).

22.Luo J, He GY. Optimization of elicitors and precursors for paclitaxel production in cell suspension culture ofTaxus chinensisin the presence of nutrient feeding.Process Biochemistry, 2004,39 (9): 1073-1079. (SCI, IF: 2.336).