楊誠

南開大學藥學院教授

楊誠,南開大學藥學院教授。招生方向:微生物、化學生物學

人物經歷


教育經歷

1983-1991 清華大學 分析化學和物理化學學士,有機化學碩士。
1992-1997 美國華盛頓州立大學,生物化學博士。

工作經歷

1991 -1992,清華大學分析化學中心,助理研究員。
1998 - 2001,美國 Molecular Structure 公司研究員,休斯敦,德克薩斯州。
2002 - 2005, Rigaku/MSC(美國)公司高級研究員,休斯頓, 德克薩斯州。
2005 - 2007,Rigaku(美國)公司學術總監和政府市場總監,休斯頓,德克薩斯州。
2007 - 2009,Rigaku(美國)公司,亞洲商業拓展部總監,休斯頓,德克薩斯州。
2009 - 南開大學藥學院,教授。

研究方向


生物化學方向。

主要貢獻


(1). The crystal structure of cytochrome P460 from Nitrosomonas europaea reveals a novel cytochrome fold and cross-linked heme. Pearson, A. R., Elmore, B. O., Yang, C., Ferrara, J. D., Hooper, A. D. & Wilmot, C. M. Biochemistry ( 2007) 46, 8340 -8349.
(2). Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target. Laponogov1, I., Veselkov. D. A., Sohi, M. K., Pan, X.-S., Achari, A., Cheng, Y., Ferrara, J. D., Fisher, L. M., Sanderson, M. R. PLoS ONE (2007) 3, 1-9.
(3). Away from the edge II: in-house Se-SAS phasing with chromium radiation H. Xu*, C. Yang*, L. Chen, I. A. Kataeva, W. Tempel, D. Lee, J. E. Habel, D. Nguyen, J. W. Pflugrath, J. D. Ferrara, W. B. Arendall III, J. S. Richardson, D. C. Richardson, Z.-J. Liu, M. G. Newton, J. P. Rose and B.-C. Wang. Acta Cryst. (2005) D61, 960-966
(4). Structural and Biochemical Characterization of CIB1 Delineates a new Family of EF-hand containing PRO proteins. H. R. Gentry, A. U. Singer, L. Betts, C. Yang, J. D. Ferrara, J. Sondek and L. V. Parise J. Biol. Chem., (2005). 280, 8407 - 8415
(5).Structural Basis for Herbicida inhibitor selectivity revealed by comparison of crystal structures of Plant and Mammalian 4-Hydroxyphenylpyruvate dioxygenases. C. Yang, J. W. Pflugrath, D. L. Camper, M. L. foster, D. J. Pernich and T. A. Walsh. Biochemistry (2004). 43(32), 10414-10423
(6). Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae. J. D. Phillips, F. G. Whitby, C. A. Warby, P. Labbe, C. Yang, J. W. Pflugrath, J. D. Ferrara, H. Robinson, J. P. Kushner, and C. P. Hill. J. Biol. Chem., (2004). 279, 38960 – 38968
(7). Away from the edge: SAD phasing from the sulfur anomalous signal measured in-house with chromium radiation. C. Yang, J. W. Pflugrath, C. N. Stence, A. Courville and J. D. Ferrara. Acta cryst. (2003). D59, 1943-1957
(8). Crystal Structures of Unligated and CN-Ligated Glycera dibranchiata Monomer Ferric Hemoglobin Components III and IV. H. J. Park*, C. Yang*, N. Treff, J. D. Satterlee and C. H. Kang. Proteins: struct., funct., (2002). 49, 49-54
(9).The application of anomalous signal of sulfur from single wavelength(CuK) for routinely phasing protein diffraction data. C. Yang and J. Pflugrath. Acta Cryst. (2001). D57 1480-1490
(10). Optics systems for the home laboratory: caveat emptor. C. Yang, A. Courville and J. D. Ferrara. Acta Cryst., (1999) D55 1681-1689
(11). Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the crystal structure of d(ACCCT). J. K. Weil, T. Min, C. Yang, C. Sutherland, N. Sinda and C. H. Kang. Acta Cryst., (1999). D55, 422-429
(12). Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4Å resolution. C. Yang, U. Curth, C. Urbanke and C. H. Kang. Nature structure biology, (1997). 4(2) 153-157
(13). Studies on liquid Crystal/Polymer Enriching Oxygen Composite Membranes C. Yang, L. Y. Wang and Y. F. Yan. Membrane science and technology (1994). 14(1)