田陽

：

：

終歷：研究

職稱：教授

學位：理學博士

學術研究課題

研究方向：電化學分析、生物分析與生物感測、光電化學及光電分析

社會兼職

《分析化學》雜誌編委

中國活性氧專業委員會委員

北京航空航天大學學士，日本東京工業大學碩士和博士，東京大學博士后(JSPS)。現任教授、博士生導師。2006年入選教育部“新世紀優秀人才”計劃和上海市“浦江人才計劃”，2011年獲中國分析測試協會科學技術獎一等獎；2013年獲得日本化學會“The Distinguished Lectureship Award”和國家自然科學基金委傑出青年基金。

致力於活性氧及氧化應激過程的分析化學研究。以活性氧及與氧化應激過程密切相關的生物小分子如氫離子等為研究對象，針對活性氧及氧化應激過程的關鍵科學問題，進行了深入而系統的研究：基於雙重識別設計與無機-有機複合表界面的研究，建立了選擇性好、靈敏度高、響應速度快的活性氧及氧化應激相關分子的分析新方法；利用所發展的分析方法，發現了細胞釋放活性氧與胞內pH、金屬離子等的關係；率先研究了氧化應激模型下、鼠腦中活性氧等生物小分子的濃度變化與生理病理活動的關係。近年來，以通訊聯繫人發表論文45篇，包括Angew. Chem. Int. Ed.、Anal. Chem.、Chem.-Eur. J.、Chem. Commun. 等。所發表論文被Chem. Rev.,J. Am. Chem. Soc.,Angew. Chem. Int. Ed.,Anal. Chem.他引1291次。

代表性論文：

1. Changqin Ding, Anwei Zhu,Yang Tian*

Functional Surface Engineering of C-Dots for Fluorescent Biosensing and in Vivo Bioimaging

Acc. Chem. Res., 2014, 47, 20-30.

2. Xiaolan Chai, Xinguang Zhou, Anwei Zhu, Limin Zhang, Yao Qin, Guoyue Shi,Yang Tian*

A Two-Channel Ratiometric Electrochemical Biosensor for In Vivo Monitoring of Copper Ions in a Rat Brain Using Specific Biomolecular Recognition and Gold Truncated Octahedral Microcages

Angew. Chem. Int. Ed., 2013,52, 8129-8133.

3. Xiangling Shao, Hui Gu, Zhen Wang, Xiaolan Chai, Yang Tian*, and Guoyue Shi*

Highly Selective Electrochemical Strategy for Monitoring of Cerebral Cu2+ Based on a Carbon Dot-TPEA Hybridized Surface

Anal. Chem., 2013,85, 418-425.

4. Linxia Li, Anwei Zhu, Yang Tian*

An electrochemical strategy for fast monitoring of ˙OH released from live cells at an electroactive FcHT-functional surface amplified by Au nanoparticles

Chem. Commun., 2013,49, 1279-1281.

5. Anwei Zhu, Qiang Qu, Xiangling Shao, Biao Kong, Yang Tian*

Carbon Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor of In Vivo Imaging of Cellular Copper Ions

Angew. Chem. Int. Ed., 2012,51, 7185-7189.

6. Biao Kong, Anwei Zhu, Changqin Ding, Xiaoming Zhao, Bo Li, and Yang Tian*

Carbon Dot-Based Inorganic–Organic Nanosystem for Two-Photon Imaging and Biosensing of pH Variation in Living Cells and Tissues

Adv. Mater., 2012,24, 5844-5848.

7. Yan Liang, Biao Kong, Anwei Zhu, Wang Zhen, Yang Tian*

A Facile and Efficient Strategy for Photoelectrochemical Detection of Cadmium Ions based on In situ Electrodeposition of CdSe Clusters on TiO Nanotubes

Chem. Commun., 2012,48, 245-247.

8. Anwei Zhu, Yan Liu, Qi Rui, Yang Tian*

Selective and Sensitive Determination of Hydroxyl Radicals Generated from Living Cells through Electrochemical Impedance Method

Chem. Commun., 2011,47, 4279-4281.

9. Biao Kong, Anwei Zhu, Yongping Luo, Yang Tian*, Yanyan Yu, Guoyue Shi

Sensitive and Selective Colorimetric Visualization of Cerebral Dopamine Based on Double Molecular Recognition

Angew. Chem. Int. Ed., 2011,50, 1837-1840.

10. Feng Zhang, Min Wen, Mingzhu Cheng, Di Liu, Yang Tian*

Pt-on-NiCo Nanostructures with Facilitated Electrocatalytic Activities for Sensitive Determination of Intracellular Thiols with Long-Term Stability

Chem-Eur. J., 2010, 16, 11115-11120.

11. Feng Zhang, Anwei Zhu, Yongping Luo, Yang Tian*, Jinhu Yang, Yao Qin*

CuO Nanosheets for Sensitive and Selective Determination of HS with High Recovery Ability

J. Phys. Chem. C, 2010, 114, 19214-19219.

12. Xiaoguang Li, Yan Liu, Anwei Zhu, Yongping Luo, Yang Tian*

Real-Time Electrochemical Monitoring of Cellular HOIntegrated with In Situ Selective Cultivation of Living Cells Based on Dual Functional Protein Microarrays at Au-TiO Surfaces

Anal. Chem., 2010, 82, 6512-6518.

13. Anwei Zhu, Yongping Luo, Yang Tian*

Switching Direction of Plasmon-Induced Photocurrents by Cytochrome C at Au-TiO Nanoparticles

Chem. Commun., 2009, 6448-6450.

14. Xiaoguang Li, Yang Tian*, Peipei Xia, Yongping Luo, Qi Rui

Fabrication of TiO and Metal Nanoparticle Microelectrode Arrays by Photolithography and Site-Selective Photocatalytic Deposition

Anal. Chem., 2009,81, 8249-8255.

15. Anwei Zhu, Yongping Luo, Yang Tian*

Plasmon-Induced Enhancement in Analytical Performance Based on Gold Nanoparticles Deposited on TiO Film

Anal. Chem., 2009,81, 7243-7247.

16. Ming Wen, Haiqing Liu, Feng Zhang, Yuanzheng Zhu, Di Liu, Yang Tian*

Amorphous FeNiPt Nanoparticles with Tunable Length for Electrocatalysis and Electrochemical Determination of Thiol

Chem. Commun., 2009, 4530-4532.

17. Yongping Luo, Yang Tian*, Qi Rui

Electrochemical Assay of Superoxide Based on Biomimetic Enzyme at Highly Conductive TiO Nanoneedles: from Principle to Applications in Living Cells

Chem. Commun., 2009, 3014-3017.

18. Yongping Luo, Haiqing Liu, Qi Rui, Yang Tian*

Detection of Extracellular HO Released from Human Liver Cancer Cells Based on TiO Nanoneedles with Enhanced Electron Transfer of Cytochrome c

Anal. Chem., 2009,81, 3035-3041.

19. Anwei Zhu, Yang Tian*, Haiqing Liu, Yongping Luo

Nanoporous Gold Film Encapsulating Cytochrome c for the Fabrication of a HO Biosensor

Biomaterials, 2009,30, 3183-3188.

20. Zifeng Deng, Qi Rui, Xia Yin, Haiqing Liu, Yang Tian*

In Vivo Detection of Superoxide Anion in Bean Sprout Based on ZnO Nanodisks with Facilitated Activity for Direct Electron Transfer of Superoxide Dismutase

Anal. Chem., 2008,80, 5839-5846。

2021年7月，入選2021年中國科學院院士增選初步候選人名單。