王麗華

蘇州大學材化部高級工程師

王麗華,女,現任蘇州大學實驗教學中心高級工程師,主要從事化工實驗教學及科研工作等。

1982年南京工業大學本科畢業,獲工學學士學位,蘇州大學環境治理與資源化研究中心成員。作為第二承擔者參加了2項國家自然科學基金項目、1項省自然科學基金項目和1項市科技項目,發表第一作者論文3篇,第二作者論文3篇,作為編委參編實驗教學教材1部。以第二發明人獲中國發明專利授權2項,獲江蘇省優秀專利獎1項(排名第二),中國石油和化學工業協會科學技術進步獎二等獎1項(排名第三) ,教育部科技進步二等獎1項(排名第四)。

參編教材


作為編委之一參編:化工原理實驗(21世紀高等院校化學實驗教學改革示範教材),南京大學出版社,2010年12月

教學論文


1.流體流動阻力實驗的改進與提高,王麗華徐慶峰,實驗室科學,(4) 57-59(2010)
2.乾燥速率曲線測定實驗設備改進的一點設想,王麗華夏雪偉,實驗室科學,(1)177-178(2009)
3.流化床乾燥實驗設備改進的設想,王麗華夏雪偉,蘇州大學學報, 61-62(2007)
(4)Xu L,Li Y,Sun H,Zhen X,Qiao C,Tian S,Hou T. Current developments of macrophage migration inhibitory factor (MIF) inhibitors. Drug Discov Today. doi: 10.1016/j.drudis.2012.12.013. [Epub ahead of print]
(5)Ye N,Neumeyer JL,Baldessarini RJ,Zhen X,Zhang A.Update 1 of: Recent Progress in Development of Dopamine Receptor Subtype-Selective Agents: Potential Therapeutics for Neurological and Psychiatric Disorders. Chem Rev. 2013 Mar 7. [Epub ahead of print].
(6)Haifeng Suna, Liyuan Zhub, Huicui Yangc, Wangke Qiana, Lin Guob, Shengbin Zhoua, Bo Gaoc, Zeng Lia, Yu Zhoua, Hualiang Jianga, Kaixian Chena, Xuechu Zhen, Hong Liu Asymmetric Total Synthesis and Identification of Tetrahydroprotoberberine Derivatives as New Antipsychotic Agents Possessing a Dopamine D1, D2 and Serotonin 5-HT1A Multi-Action Profile. BIOORG. MED. CHEM. ;21(4):856-68
(7)Liu CL, Gao M, Jin GZ, Zhen X. GABA Neurons in the Ventral Tegmental Area Responding to Peripheral Sensory Input. PLoS One. 2012;7(12):e51507. doi: 10.1371.
(8)Qian W, Lu W, Sun H, Li Z, Zhu L, Zhao R, Zhang L, Zhou S, Zhou Y, Jiang H, Zhen X, Liu H. Design, synthesis, and pharmacological evaluation of novel tetrahydroprotoberberine derivatives: selective inhibitors of dopamine D receptor.Bioorg Med Chem. 2012, 20(15):4862-71.
(9)Zheng YY,Guo L,Zhen XC,Li JQ. Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors. Eur J Med Chem. 2012, 54:123-36.
(10)Xu Z,Dong S,Du D,Jiang N,Sun P,Wang H,Yin L,Zhang X,Cao X,Zhen X,Hu Y. Generation and characterization of hD(5) and C-terminal Mutant hD(5m) transgenic rats. Brain Res. 2012, 1448:27-41.
(11)Chu HY, Wu Q, Zhou S, Cao X, Zhang A, Jin GZ, Hu GY, Zhen X. SKF83959 suppresses excitatory synaptic transmission in rat hippocampus via a dopamine receptor-independent mechanism.J Neurosci Res. 2011 Aug;89(8):1259-66.
(12)Zhang H, Ye N, Zhou S, Guo L, Zheng L, Liu Z, Gao B, Zhen X, Zhang A. Identification of N-Propylnoraporphin-11-yl 5-(1,2-Dithiolan-3-yl)pentanoate as a New Anti-Parkinson's Agent Possessing a Dopamine D(2) and Serotonin 5-HT(1A) Dual-Agonist Profile. J Med Chem. 2011 Jun 14. 54(13):4324-38.
(13)Ye N, Wu Q, Zhu L, Zheng L, Gao B, Zhen X, Zhang A. Further SAR study on 11-O-substituted aporphine analogues: Identification of highly potent dopamine D(3) receptor ligands. Bioorg Med Chem. 2011 Mar 15; 19(6):1999-2008.
(14)Chu HY, Yang Z, Zhao B, Jin GZ, Hu GY, Zhen X*. Activation of phosphatidylinositol-linked D1-like receptors increases spontaneous glutamate release in rat somatosensory cortical neurons in vitro. Brain Res. 2010 Jul 9; 1343:20-7.