范建華

2007/09-2012/11，華東理工大學生物工程學院，生物化工專業，碩博連讀

2011/05-2012/06，中科院青島生物能源與過程研究所，聯合培養

2009/03-2010/01，中科院遺傳與發育生物學研究所，聯合培養

2003/09-2007/07，華東理工大學生物工程學院，生物科學專業，本科

2012/12-2014/12，華東理工大學生物反應器工程國家重點實驗室，師資博士后/助理研究員

2015/01-2021/6，華東理工大學生物工程學院，歷任講師、副教授、碩士生導師

2016/10-2017/10，Carnegie Institution for Science at Stanford University，訪問學者

2021/07-，華東理工大學生物工程學院，副教授，博士生導師

近年來一直從事微生物/微藻種質選育、基因工程、脂質/糖類代謝、光合固碳機制等研究。主要方向為利用正向/反向遺傳學/合成生物學研究光合藻類細胞物質與能量傳遞的分子調控機制。

作為負責人承擔國家自然科學基金、上海市自然科學基金、973計劃子課題等多個國家級/省部級項目。已在包括植物學Top期刊Plant Physiology、生物工程與應用微生物Top期刊Biotechnology for Biofuels等雜誌上發表SCI等論文20多篇，Google Scholar總被引用超過600次，單篇引用超120次；申請發明專利14項。擔任Frontiers in Plant Science和Frontiers in Bioengineering and Biotechnology客座編委。Biotechnology for Biofuels、Biotechnology Journal、Algal Research、Applied Biochemistry and Biotechnology等期刊審稿人。主講本科生《生物化學實驗》、《進化生物學》等課程。指導國家級/上海市級“大學生創新創業訓練計劃”、iGEM競賽、Bio-maker創新活動等。

[1]Weiliang Wang,Tingting Wei, Jianhua Fan, et al.Repeated mutagenic effects ofCo-γ irradiation coupled with high-throughput screening improves lipid accumulation in mutant strains of the microalgaeChlorella pyrenoidosaas a feedstock for bioenergy.Algal Research, 2018, 33, 71-77. IF=3.99, Q1

[2]Jianhua Fan*, Lvhong Zheng, Yunpeng Bai, Shai Saroussi, Arthur Grossman. Flocculation of Chlamydomonasreinhardtii with different phenotypic traits by metal cations and high pH.Frontiers in Plant Science, 2017, 8:1997.（*corresponding author）IF=4.29, Q1

[3]Jianhua Fan*, Lvhong Zheng. Acclimation to NaCl and light stress of heterotrophic Chlamydomonasreinhardtii for lipid accumulation.Journal of Bioscience and Bioengineering, 2017, 124(3), 302-308.（*corresponding author）IF=2.24, Q2

[4]Conglin Run, Lei Fang, Jianhua Fan*, et al. Stable nuclear transformation of the industrial alga Chlorella pyrenoidosa.Algal Research, 2016, 17, 196-201.（*corresponding author）IF=3.99, Q1

[5]Jianhua Fan*, Hui Xu, Yuanguang Li*. Transcriptome-Based Global Analysis of Gene Expression in Response to Carbon Dioxide Deprivation in the Green Algae Chlorella pyrenoidosa.Algal Research, 2016,16, 12-19.（*corresponding author）IF=3.99, Q1

[6]Jianhua Fan, Kang Ning, Xiaowei Zeng, Jian Xu*, Yuanguang Li*, et al. Genomic Foundation of Starch-to-Lipid Switch in Oleaginous Chlorella spp.Plant Physiology, 2015, 169(4):2444-2461. IF=6.46, Q1 Top

[7]Jianhua Fan, Hui Xu, Yuanchan Luo, Minxi Wan, Jianke Huang, Weiliang Wang, Yuanguang Li*. Impacts of COconcentration on growth, lipid accumulation and carbon concentrating mechanism related genes expression in oleaginous Chlorella.Applied Microbiology and Biotechnology, 2015, 99(5):2451-2462. IF=3.42, Q1

[8]Minxi Wan, Zhen Zhang, Jun Wang, Jianke Huang, Jianhua Fan, Anquan Yu, Weiliang Wang, Yuanguang Li*. Sequential heterotrophy-dilution-photoinduction cultivation of Haematococcuspluvialis for efficient production of astaxanthin.Bioresource Technology, 2015, 198: 557-563.IF=5.65, Q1

[9]Jianhua Fan, Yanbin Cui, Minxi Wan, Weiliang Wang, Yuanguang Li*. Lipid accumulation and biosynthesis genes response of the oleaginous Chlorella pyrenoidosa under three nutrition stressors.Biotechnology for Biofuels, 2014, 7:17. IF=5.20, Q1 Top

[10]Jianhua Fan, Yanbin Cui, Yang Zhou, Minxi Wan, Weiliang Wang, JingliXie, Yuanguang Li*. The effect of nutrition pattern alteration on Chlorella pyrenoidosa growth, lipid biosynthesis-related gene transcription.Bioresource Technology, 2014, 164:214-220. IF=5.65, Q1

[11]Jianke Huang, Yuanguang Li*, Minxi Wan, Yi Yan, Fei Feng, Xiaoxing Qu, Jun Wang, Guomin Shen, Wei Li*, Jianhua Fan, Weiliang Wang. Novel flat-plate photobioreactors for microalgae cultivation with special mixers to promote mixing along the light gradient.Bioresource Technology, 2014, 159:8-16. IF=5.65, Q1

[12]Minxi Wan, DongmeiHou, Yuanguang Li*, Jianhua Fan, Jianke Huang, Songtao Liang, Weiliang Wang, Ronghua Pan, Jun Wang, Shulan Li. The effective photoinduction of Haematococcuspluvialis for accumulating astaxanthin with attached cultivation.Bioresource Technology, 2014, 163:26-32. IF=5.65, Q1

[13]Minxi Wan, Jingkui Zhang, DongmeiHou, Jianhua Fan, Yuanguang Li*, Jianke Huang, Jun Wang. The effect of temperature on cell growth and astaxanthin accumulation of Haematococcuspluvialis during a light–dark cyclic cultivation.Bioresource Technology, 2014, 167, 276-283. IF=5.65, Q1

[14]Jianhua Fan, Yanbin Cui, Jianke Huang, Weiliang Wang, Weibo Yin, Zanmin Hu*, Yuanguang Li*. Suppression subtractive hybridization reveals transcript profiling of chlorella under heterotrophy to photoautotrophy transition.PLoS One, 2012, 7:1-15. IF=2.81, Q2

[15]Jianhua Fan, Jianke Huang, Yuanguang Li*, Feifei Han, Jun Wang, Xinwu Li, Weiliang Wang, Shulan Li. Sequential heterotrophy-dilution-photoinduction cultivation for efficient microalgal biomass and lipid production.Bioresource Technology, 2012, 112:206-211. IF=5.65, Q1

[16]Feifei Han, Jianke Huang, Yuanguang Li*, Weiliang Wang, Jun Wang, Jianhua Fan, Guomin Shen. Enhancement of microalgal biomass and lipid productivities by a model of photoautotrophic culture with heterotrophic cells as seed.Bioresource Technology, 2012, 118:431-437. IF=5.65, Q1