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曹鑫

上海有機化學研究所副研究員

簡歷


1999.9-2003.6,本科,中國藥科大學,藥學理科基地班;
2003.9-2008.6,博士研究生,中國藥科大學,藥學院,藥物化學專業
2008.6-2009.1,項目經理,江蘇先聲藥物研究有限公司;
2009.2-2011.1,博士后,中科院上海有機化學研究所,生命有機國家重點實驗室;
2011.1-中科院上海有機化學研究所,生命有機國家重點實驗室;
其中:2013.9-2014.9,哈佛大學,化學與化學生物學系(Harvard University, Department of Chemistry & Chemical Biology),Prof. Yoshito Kishi Group,訪問學者/博士后.

研究方向


糖化學研究,具有重要生理活性的寡糖、糖綴合物及其它天然產物的合成及開發;新型抗腫瘤藥物的合成、活性及機制研究.

代表論著


1) Biao Yu, Xin Cao. 2-(1-Hexyn-1-yl)benzoic Acid (2014), Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons Ltd.
2) Y. Y. Ma, Xin Cao*, B. Yu*. Design and Synthesis of Nerium indicum Sourced Oligosaccharide Library And Its Neuron Protective Effects. Carbo. Res., 2013, 377, 63-74.
3) X. L. Lu, Xin Cao*, B. H. Jiao, et al. Novel Patented Src Kinase Inhibitor. Current Med. Chem. 2012, 1821-1829.
4) Xin Cao, Q. D. You*, Z. Y. Li, et al. Microwave-assisted simple synthesis of quinolone derivatives. Synthetic Commun. 2009, 39, 4375–4383.
5) Xin Cao, Q. D. You*, Z. Y. Li, et al. The Design, Synthesis and Anticancer effects of 4-Heteroarylamino-3- cyanoquinolines as Dual Inhibitors of c-Src and iNOS. Acta Pharma. Sinica. 2009, 44, 288-295.
6) Xin Cao, Q. D. You*, Z. Y. Li, et al. Design and Synthesis of 7-Alkoxy-4- heteroarylamino-3-quinoline carbonitriles as Dual Inhibitors of c-Src Kinase and Nitric Oxide Synthase. Bioorg. Med. Chem. 2008, 16, 5890–5898.