張書聖

1999年10月晉陞為教授。

2002年9月被南京工業大學遴選為博士生導師；11月被魯南製藥股份有限公司聘為博士后工作站指導教師。

2003年9月被青島科技大學遴選為博士生導師。現指導在讀博士研究生9人，碩士研究生10人。

2012年7月調至臨沂大學工作。

2015年至今任臨沂大學校長。

曾任青島科技大學化學與分子工程學院院長。現任臨沂大學學術部部長兼科技處處長。

2003年以來，作為項目負責人承擔課題9項，其中：國家自然科學基金2項，教育部新世紀優秀人才支持計劃1項，

青島市科技將才專項計劃1項，電分析化學國家重點實驗室基金1項，山東省自然科學基金-重點項目2項，山東省優秀中青年科學家獎勵基金2項，山東省教育廳科技計劃1項，青島市科技發展規劃1項。

2005年6月通過山東省科技廳組織的鑒定項目1項。

2006年5月通過山東省教育廳組織的鑒定項目1項。

申報發明專利32項，已進入實審21項。出版專(譯)著4部。

2002年以來在國際國內重要學術刊物上發表第一作者SCI收錄論文40篇，代表論文如下：

1. Sai Bi, Yameng Yan, Shuangyuan Hao, Shusheng Zhang*

Colorimetric Logic Gates Based on Supramolecular Constructs of DNAzymes Responding to Ion Input Signals

Angew. Chem. Int. Ed., 2010, 49(26): 4438~4442（IF=11.829）

2. Wei Wang, Lin Li, Shufeng Liu, Cuiping Ma, Shusheng Zhang*

Determination of physiological thiols by electrochemical detection with piazselenole and its application in rat breast cancer cells 4T-1

J. Am. Chem. Soc., 2008, 130: 10846~10847（IF=8.58）

3. Xuemei Li, Xiaoyan Yang, Shusheng Zhang*

Electrochemical enzyme immunoassay using model labels

Trends in Anal. Chem., 2008, 27(6): 543~553（IF=6.546）

4. Kongcheng Hu, Dongxiao Lan, Xuemei Li, Shusheng Zhang*

Chronocoulometric Detection of DNA Hybridization Using reporter DNA Probe Modified with Au Nanoparticles Based on porous gold leaf electrode

Anal. Chem., 2008, 80: 9124~9130（IF=5.214）

5. Caifeng Ding, Xiangling Li, Ying Ge, Shusheng Zhang*

Ultrasensitive Fluorescence Detection of Telomerase Activity in Cancer Cells Based on Isothermal Circular Strand-displacement Polymerization Reaction

Anal. Chem., 2010, 82 (7): 2850~2855（IF=5.214）

6. Sai Bi, Li Li, Shusheng Zhang*

Triggered Polycatenated DNA Scaffolds for DNA Sensors and Aptasensors by a Combination of Rolling Circle Amplification and DNAzyme Amplification

Anal. Chem., 2010, 82(22): 9447~9454（IF=5.214）

7. Guifen Jie, Lei Wang, Jinxin Yuan, Shusheng Zhang*

Versatile Electrochemiluminescence Assays for Cancer Cells Based on Dendrimer/CdSe-ZnS-Quantum Dot Nanoclusters

Anal. Chem., 2011, doi: 10.1021/ac200383z（IF=5.214）

8. Shu-sheng Zhang*, Hua Zhong, Cai-feng Ding*

Ultrasensitive Flow Injection Chemiluminescence Detection of DNA Hybridization Using signal DNA probe modified with NanoAu and NanoCuS Tags

Anal. Chem., 2008, 80(19): 7206~7212（IF=5.214）

9. Shu-Sheng Zhang*, Jian-ping Xia, Xue-Mei Li*

Electrochemical Biosensor for Detection of Adenosine Based on Structure-Switching Aptamer and Amplification with Reporter Probe DNA Modified Au Nanoparticles

Anal. Chem., 2008, 80 (22): 8382~8388（IF=5.214）

10. Shu-sheng Zhang*, Ya-meng Yan, Sai Bi*

Design of Molecular Beacon as Signaling Probes for ATP Detection in Cancer Cells Based on Chemiluminescence Resonance Energy Transfer

Anal. Chem., 2009, 81(21): 8695~8701（IF=5.214）

11. Sai Bi, Yameng Yan, Xiaoyan Yang, Shu-sheng Zhang*

Gold Nanolabels for New Enhanced Chemiluminescence Immunoassay of Alpha-fetoprotein Based on Magnetic Beads

Chem.-Euro. J., 2009, 15: 4704~4709（IF=5.382）

12. Caifeng Ding, Ying Ge, Shu-sheng Zhang*

Electrochemical and Electrochemiluminescence Determination of Cancer Cells Based on Aptamers and Magnetic Beads

Chem.-Euro. J., 2010, 16: 10707~10714（IF=5.382）

13. Hui Zhang, Congcong Fang, Shusheng Zhang*

Electrochemical Determination of Adenosine Triphosphate in Cancer Cells Amplified with Autonomous Bio-bar-code DNA Machine

Chem.-Euro. J., 2010, 16: 12434~12439（IF=5.382）

14. Guifen Jie, Lei Wang, Shusheng Zhang*

Magnetic Electrochemiluminescent Hybrid Nanostructures of Fe3O4/CdSe@CdS-Quantum Dots/ Polyelectrolytes for Highly Efficient Immunosensing of Cancer Biomarker Protein

Chem.-Euro. J., 2011, 17: 641~648（IF=5.382）

15. Hui Zhang, Congcong Fang, Shusheng Zhang*

Ultrasensitive Electrochemical Analysis of Two-component Analytes by An Autonomous DNA Machine Worked in Two-cycle Modes

Chem.-Euro. J., 2011, 17(27) : 7531~7537（IF=5.476）

16. Xue-mei Li, Jinming Liu, Shu-sheng Zhang*

Electrochemical Biosensor for Simultaneous Analysis of Two Analytes Based on a Dual-Aptamer DNA Sequence

Chem. Commun., 2010, 46: 595~597（IF=5.504）

17. Rui Ren, Cuicui Leng, Shusheng Zhang*

A Cell sensor based on aptamer recognition and electrode-based circular strand-replacement DNA polymerization

Chem. Commun., 2010, 46: 5758 - 5760（IF=5.504）

18. Hua Zhong, Xi Lei, Xu Hun, Shu-sheng Zhang*

Design of One-to-one Recognition DNA Probe Based on Triple Au Nanoparticles Bio Bar Codes and its Application in the Electrochemical DNA Biosensor

Chem. Commun., 2009, 45: 6958~6960（IF=5.504）

19. Yingshu Guo, Xueping Jia, Shusheng Zhang*

DNA cycle amplification device on magnetic microbeads for determination of thrombin based on graphene oxide enhancing signal-on electrochemiluminescence

Chem. Commun., 2011, 47(2): 725~727（IF=5.504）

20. Yingshu Guo, Yuanshun Sun, Shusheng Zhang*

Electrochemiluminescence induced photoelectrochemistry for sensing of the DNA based on DNA-linked CdS NPs superstructure with intercalator molecules

Chem. Commun., 2011, 47 (5): 1595~1597（IF=5.504）

21. Sai Bi, Hong Zhou, Shu-sheng Zhang*

Ultrasensitive Flow Injection Chemiluminescence Detection of DNA Hybridization Based on Bio-Bar-Code Functionalized Magnetic Nanoparticle Label

Chem. Commun., 2009, 37: 5567~5569（IF=5.504）

22. Sai Bi, Shuangyuan Hao, Li Li, Shusheng Zhang*

Bio-Bar-Code Dendrimer-like DNA as Signal Amplifier for Cancerous Cells Assay Using Ruthenium Nanoparticle-Based Ultrasensitive Chemiluminescence Detection

Chem. Commun., 2010, 46: 6093~6095（IF=5.504）

23. Caifeng Ding, Hui Li, Xiangling Li, Shusheng Zhang*

A new strategy of photoelectrochemical analysis with light source free based on isoluminol labelled chemiluminescence probe

Chem. Commun., 2010, 46(42): 7990~7992（IF=5.504）

24. Guifen Jie, Ping Liu, Shusheng Zhang*

Highly Enhanced Electrochemiluminescence of Novel Gold/Silica/CdSe-CdS Nanostructures for Ultrasensitive Immunoassay of Protein Tumor Marker

Chem. Commun., 2010, 46: 1323~1325（IF=5.504）

25. Sai Bi, Jilei Zhang, Shusheng Zhang*

Ultrasensitive and Selective DNA Detection Based on Nicking Endonuclease Assisted Signal Amplification and Its Application in Cancer Cell Detection

Chem. Commun., 2010, 46: 5509~5511（IF=5.504）

26. Chunxiang Li, Juan Lin, Yingshu Guo, Shusheng Zhang*

An Electrochemiluminescent Reagent of Cyclometalated Iridium Complex-Based DNA Biosensor and its Application in Cancer Cell Detection

Chem. Commun., 2011, 47 (15): 4442~4444（IF=5.787）

27. Xiaoru Zhang, Shuguo Li, Xia Jin, Shusheng Zhang*

New Photoelectrochemical Aptasensor for the Thrombin Detection Based on Functionalized Graphene and CdSe Nanoparticles Multilayers

Chem. Commun., 2011, 47 (17): 4929~4931（IF=5.787）

長期以來一直從事教學、科研工作。

2012年8月擔任山東省首席專家。

2017年1月張書聖科技領軍人才創新工作室揭牌。

2015年入選泰山學者攀登計劃。

擔任生態化工教育部重點實驗室主任，生態化工國家重點實驗室培育基地主任，山東省生化分析重點實驗室主任，《分析化學》編委。