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張根發

北京師範大學生命科學學院教授

張根發,北京師範大學生命科學學院博士生導師,教授,是具有國際影響力的著名遺傳學家、優秀的教育和科研工作者。任多屆中國遺傳學會理事,任第11、12屆中國植物學會理事,擔任許多國內外重要學術雜誌的編委和審稿人。活躍在相關的遺傳學教學科研,植物分子遺傳學,植物抗逆分子生物學研究領域。

個人簡介


張根發教授是具有國際影響力的著名遺傳學家、優秀的教育和科研工作者,北京師範大學生命科學學院博士生導師。自1990年畢業獲得博士學位以來,作為博士后和高級訪問學者先後訪問過英國、以色列和美國開展合作研究。在多年的科研實踐中,承擔和完成30多項國家科研項目,包括國家自然科學基金面上項目、重點重大項目,國家973、863、948項目,以及北京市自然科學項目等。
已在國際著名雜誌,如Plant Cell, New Phytologist, Plant Physiology, FEBS Letters,國內核心期刊以上學術雜誌發表論文150多篇,出版專著和教材等著作16部,特別是《好好芭資源生物學》一書受到國家科學出版基金資助出版,具有很高的原創性;在國內外有重要的影響力。多年的科學研究成果豐富,也有多項成果獲得國家各種獎項,包括獲得省級科技進步二等獎2項,教育部科技進步獎1項。張教授不僅科研工作優異,成果豐碩;在教育教學研究中也取得了許多重要成就,特別值得一提的是2007年主持的遺傳學雙語教學課程被評為首次國家雙語教學示範課程;教學項目研究成果獲得2008年北京師範大學教育成果一等獎。從事高等教育工作幾十年來,作為博士生導師已培養博碩士研究生60多名。

研究內容


植物抗逆分子遺傳、植物基因資源、蛋白質組學基因表達調控、基因功能的挖掘與評價等研究工作。特別是抗旱、耐鹽相關基因及其啟動因子的克隆、鑒定和功能及其可能的應用;
模式植物擬南芥的抗逆機理的功能基因組學、蛋白質組學和抗逆基因表達調控的分子遺傳機理;研究植物生長,逆境響應中的表觀遺傳、以及蛋白翻譯后修飾的調控作用和分子機理。

代表性成果


專著

● ● 張根發著,特種基因資源植物,旱地新興油料作物—《好好芭資源生物學》,科學出版社,2008年,北京(中國科學院科學出版基金資助)。
● ● 張根發,譚信楊澤梁前進譯,遺傳變異分析實驗指南(美)韋納 等主編,2010.05,科學出版社,北京。

研究性論文

1. Zijin Liu, Lamei Zheng, Li Pu, Xiaofeng Ma, Xing Wang, Yu Wu, Hainan Ming, Qing Wang, Genfa Zhang*. ENO2 affects the seed size and weight by adjusting cytokinin content and forming ENO2-bZIP75 complex in Arabidopsis thaliana. Frontiers in Plant Science, 2020, 11, 574316. 
2. Zijin Liu#, Yonghua Zhang#, Xiaofeng Ma, Pan Ye, Fei Gao, Xiaofeng Li, Yijun Zhou, Zihan Shi, Huimei Cheng, Chaoxing Zheng, Hongjie Li*, Genfa Zhang*. Biological functions of Arabidopsis thaliana MBP-like protein encoded by ENO2 in the response to drought and salt stresses. Physiologia Plantarum, 2019, 167(2): 13013. 
3. Liu Zi-Jin, Yong-Hua Zhang, Xiao-Feng Ma, Pan Ye1, Fei Gao, Xiao-Feng Li, Yi-Jun Zhou, Zi-Han Shi1, Hui-Mei Cheng, Chao-Xing Zheng, Hong-Jie Li, Gen-Fa Zhang*. Biological functions of Arabidopsis MBP-1-like protein (AtMBP-1) encoded by ENO2 in the response to drought and salt stresses. Physiologia Plantarum, 2019, doi/10.1111/ppl.13013.
4. Cao, Shilin, Ying Wang, Zhiqiang Li, Wei Shi, Fei Gao*, Yijun Zhou, Jinchao Feng, Genfa Zhang*. Genome-wide Identification and Expression Analyses of the Chitinases under Cold and Osmotic stress in Ammopiptanthus nanus. Genes. 2019,10,472, doi: 10.3390 /genes10060472. 
5. Xing Wang, Jilong Zhang, Weimin Sun, Xiuxiu Feng, Hongjie Li, Genfa Zhang*. Overexpressing a jojoba aquaporin gene, ScPIP1, in Arabidopsis thaliana enhances plant tolerance to drought and salt. [J] The International Journal of Molecular Sciences. Int. J. Mol. Sci. 2019, 20, 153; doi:10.3390/ijms20010153.
6. Gao Fei., Pengju Ma, Yingxin Wu, Yijun Zhou, Gnefa Zhang*.Quantitative proteomic analysis of the response to cold stress in Jojoba, a tropical woody crop [J] the International Journal of Molecular Sciences. 2019, 20, 243; doi: 10.3390/ ijms20020243.
7. Chen C, Zhang YH, Ye P, Ma XF, Zheng CX, Zhang GF*. ENO2 knock-out mutants in Arabidopsis modify the regulation of the gene expression response to NaCl stress [J]. Molecular Biology Reports. 2018. https://doi.org/10.1007/s11033-018-4292-7.
8. Yonghua Zhang, Chao Chen, Shi Zihan, Cheng Huimei, Bing Jie, Ma Xiaofeng, Zheng Chaoxing, Li Hongjie, Zhang Genfa*. Identification of salinity-related genes in ENO2 variant (eno2-) of Arabidopsis thaliana. Journal of Integrative Agriculture. Journal of Integrative Agriculture. 2018, 17 (1):94-110. DOI: 10.1016 /s 2095–3119 (17) 61720-9.
9. Zeqin Li, Jilong Zhang, Jingxiao Li, Hongjie Li, Genfa Zhang*. The Function and Regulation Mechanism of TsApx6 from Thellungiella Salsuginea in Response to Salinity and Drought Stresses. [J]. PLoS One, 2016, 11(4): e0154042.
10. Zeqin Li, Jingxiao Li, Hongjie Li, Zihan Shi, Genfa Zhang*. Overexpression of TsApx1 from Thellungiella salsuginea improves abiotic stress tolerance in transgenic Arabidopsis thaliana. BIOLOGIA PLANTARUM 59 (3):497-506, 2015. DOI: 10.1007/s 10535-015-0533-y.
11. Yu Haichan, Jin Zhao, Jing Xu, Xiaoqu Li, Fengshou Zhang, Yugang Wang, Christopher Carr, Jun Zhang and Genfa Zhang*, Detection of Changes in DNA Methylation Induced by Low-Energy Ion Implantation in Arabidopsis thaliana. 2011, RADIATION RESEARCH 175, 599–609. DOI: 10.1667/RR2209.1.
12. Liu X, Sun W, Li Z, Bai R, Li J, Shi Z, Geng H, Zheng Y, Zhang J, Zhang G., Overexpression of ScMnSOD, a SOD gene derived from Jojoba, in Arabidopsis confers its role in drought stress tolerance. Journal of Integrative Agriculture,2013, 12(10): 1722-1730.
13. Gao Fei, Yijun Zhou, Weipin Zhu, Xiaofeng Li, Liumin Fan, Genfa Zhang*, Proteomic analysis of cold stress-responsive proteins in Thellungiella rosette leaves. Planta. 2009 (230):1033-1046. DOI 10.1007 /s00425-009-1003-6.
14. Changhui Sun, Jun Fang, Taolan Zhao, Bo Xua, Fantao Zhang, Linchuan Liu, Jiuyou Tang, Genfa Zhang, Xiaojian Deng, Fan Chen, Qian Qian, Xiaofeng Cao, The Histone Methyltransferase SDG724 Mediates H3K36me2/3 Deposition at MADS50 and RFT1 and Promotes Flowering in Rice. Plant Cell. 2012. (8):3235-47. Aug 14. doi:10.1105/tpc.112.101436.

綜述

15. Liu Zijin, Aileen Zhang, Lamei Zheng, Johnathan Abou-Fadel, Jun Zhang and Genfa Zhang*. The Biological Significance and Regulatory Mechanism of c-Myc Binding Protein 1 (MBP-1). [J] The International Journal of Molecular Sciences. 2018, 19, 3868; doi:10.3390/ijms19123868.
16. Zhang Jun, Rod Chiodini, Ahmed Badr, Genfa Zhang. The impact of next-generation sequencing on genomics. JGG,Journal of Genetics and genomics. 38(2011):95-109 doi:10.1016/ j.jgg.2011.02.003 (2011) 1e15, Best review paper in 2013.