李江華

姓名：李江華

出生年月：1966年4月6日

• 近5年在發表論文80餘篇（SCI收錄60餘篇）。

• 其中代表性的論文如下:

• Zhang Chunyu, Liu Long*,Teng Liping, Chen Jinghua, Liu Jian, Li Jianghua,Du Guocheng, Chen Jian*.Metabolic engineering of Escherichia coli BL21 for biosynthesis of heparosan, a bioengineered heparin precursor. Metab Eng. 2012, 14(5):521-527.

• Liu Yanfeng, Liu Long, Shin Hyun-dong, Chen Rachel R, Li Jianghua, Du Guocheng, Chen Jian.Pathway engineering of Bacillus subtilis for microbial production of N-acetylglucosamine. Metab Eng. 2013, 19: 107-115.

• Liu Yanfeng, Zhu Yanqiu, Ma Wenlong, Shin Hyun-dong, Li Jianghua, Liu Long, Du Guochen, Chen Jian. Spatial modulation of key pathway enzymes by DNA-guided scaffold system and respiration chain engineering for improved N-acetylglucosamine production by Bacillus subtilis. Metab Eng. 2014,24: 61-69.

• Liu Yanfeng, Zhu Yanqiu, Li Jianghua, Shin Hyun-dong，Chen Rachel R. Du Guochen, Liu Long, Chen Jian. Modular pathway engineering of Bacillus subtilis for improved N-acetylglucosamine production. Metab Eng. 2014, 23: 42-52.

• Han Ruizhi, Li Jianghua, Shin Hyun-dong，Rachel R. Chen，Du Guochen, Liu Long, Chen Jian. Recent advances in discovery, heterologous expression, and molecular engineering of cyclodextrin glycosyltransferase for versatile applications. Biotechnology Advances, 2014, 32: 415-428.

• Zhuge Xin, Li Jianghua, Shin Hyun-dong, Chen Rachel R., Du Guocheng, Liu Long, Chen Jian. Development of a Propionibacterium-Escherichia coli shuttle vector as a useful tool for metabolic engineering of Propionibacterium jensenii, an efficient producer of propionic acid. Applied and Environmental Microbiology, 2013, 79: 4595-4602.

• Yang Haiquan, Liu Long, Shin Hyun-dong, Chen Rachel R, Li Jianghua, Du Guocheng, Chen Jian. Integrating terminal truncation and oligopeptide fusion as a novel protein engineering strategy to improve specific activity and catalytic efficiency: Alkaline α-amylase as a case study. Applied and Environmental Microbiology, 2013,79: 6429-6438.

• Han Ruizhi, Shin Hyun-dong, Chen Rachel R., Li Jianghua, Du Guocheng, Liu Long, Chen Jian. Carbohydrate binding module fusion of cyclodextrin glycosyltransferase enables the efficient synthesis of 2-O-D-glucopyranosyl-L-ascorbic acid with soluble starch as the glycosyl donor. Applied and Environmental Microbiology, 2013, 79: 3234-3240.

• Yang Haiquan, Lu Xinyao, Liu Long, Shin Hyun-dong, Chen Rachel R, Li Jianghua, Du Guocheng, Chen Jian. Fusion of an Oligopeptide to the N Terminus of an Alkaline-Amylase from Alkalimonas amylolytica Simultaneously Improves the Enzyme’s Catalytic Efficiency, Thermal Stability, and Resistance to Oxidation. Applied and Environmental Microbiology. 2013, 79: 3049-3058.

• Liu Long,Zhu Yunfeng, Li Jianghua,Wang Miao, Lee Pengsoon, Du Guocheng, Chen Jian. Microbial production of propionic acid from propionibacteria: Current state, challenges and perspectives. Crit Rev Biotechnol. 2012, 32(4): 374-381.

近5年來主持或完成863計劃、江蘇省科技支撐計劃項目2項。

其中代表性的科研項目如下:

（1）“L-異亮氨酸高效清潔生產的關鍵技術”，“863”項目（2007AA02Z229），2007-2010

（2）“紡織精鍊用高效酶製劑製備和應用”，江蘇省科技支撐技術（BE200900022），2009-2010

• 6項成果被鑒定達到國內領先或國際先進水平。1項科研成果獲國家技術發明二等獎，1項科研成果獲教育部科技進步二等獎，2項科研成果獲中國輕工業聯合會科技發明一等獎。

• 其中代表性的成果獎勵如下:

• （1）“棉織物染整前處理關鍵酶製劑的發酵生產和應用技術”，國家技術發明二等獎，第三完成人，2012年

• （2）“L-異亮氨酸高效清潔發酵生產”，教育部科技進步二等獎，第一完成人，2013年

• （3）“發酵法生產用於紡織品染整加工的鹼性果膠酶和過氧化氫酶”，中國輕工業聯合會科技發明一等獎，第三完成人，2010年

• （4）“新型有機酸的發酵法製備技術” ，中國輕工業聯合會科技發明一等獎，第四完成人，2013年