白春學

醫生、學者

白春學,主任醫師,教授。上海市領軍人才。現任復旦大學新農村研究院智慧醫療研究所所長,上海市呼吸內科臨床質控中心主任,上海市“重中之重”臨床重點學科呼吸內科負責人,上海市青浦雲加端物聯網醫學中心實驗室主任,國家衛計委臨床重點專科呼吸內科負責人,上海市呼吸病研究所所長,復旦大學呼吸病研究所所長,中國肺癌防治聯盟主席,中國醫師協會呼吸分會副會長。

擅長疾病


擅長戒煙、肺腫瘤、肺血管病、慢性氣道疾病等呼吸病診治。
肺癌;e-Health,物聯網醫學;慢性阻塞性肺疾病;急性肺損傷;急性呼吸窘迫綜合征

個人履歷


從事呼吸內科和呼吸危重醫學,主要研究方向為肺損傷和肺癌的分子發病機制和治療。獲得28項科研課題資助,包括牽頭國家自然科學基金重點項目和參加美國NIH等重點課題。已發表論文340餘篇,其中SCI索引雜誌論文50餘篇,影響因子累計210餘分。主編《呼吸系統疾病診斷和鑒別診斷學》、《急性呼吸窘迫綜合征》、《呼吸病診治剛要和質控要求》和《呼吸系統疾病的核醫學檢查》,參編多部專著和教科書。
在國際上最早提出應用無線感測技術監測呼吸功能並成功研究出樣機,2009年ATS會刊(ATS NEWS | VOL.35 NO.7/8,)名人錄為此刊登了專題報道,目前正在研究無線感測技術在心肺功能監測的全面應用。此外,還率先應用生物物理技術發展動態實時血氣分析儀,獲得“一種雙鏈RNA及其用途”(專利號:ZL03115489. 1)和“在體實時光敏感血液鈉離子感測器及其製備方法”等發明專利(專利號: ZL20051 0110731.2)。
先後獲2009年國家科技進步二等獎:“呼吸衰竭的發病機理與治療研究”(第2完成人);2006年中華醫學一等獎:“呼吸支持技術臨床應用研究”(第3完成人);2005和2009年分別獲得上海市優秀髮明選拔賽一等獎和金獎(第1完成人);以及“國家醫藥衛生科技進步三等獎”兩次和其它多項獎勵。

教育經歷


1997年2月-1998年11月在美國加州大學舊金山分校做博士后研究
1986年-1989年就讀於原上海醫科大學研究生院,獲博士學位
1985年5月-1985年10月在WHO/日本進修結核防治
1979年-1982年就讀於北京中國協和醫科大學研究生院,獲碩士學位
1972年-1975年就讀於哈爾濱醫科大學醫療系 

工作經歷


學術任職


中國肺癌防治聯盟主席
中國醫師協會呼吸分會副會長
上海市控煙協會會長
中國非公立醫療機構協會物聯網醫療分會會長

主要學術兼職


亞太呼吸學會Treasuer, 主要領導人;
EU-China IoT Advisory Group中國唯一醫學專家,參編EU-China Joint White Paper on the Internet of Things;
ATS胸部腫瘤學委員和科委會委員

雜誌審稿人


(1)NEJM (IF= 72.406);
(2)Chest(IF=7.483);
(3)AJRCCM(IF= 16.494);
(4)AJRCMB(IF=3.984);
(5)AJM (IF=5.003);
(6)Critical Care Medicine(IF=6.312);
(7)RESPIROLOGY(IF=4.756)。

著作編委


(1)KeAi (Elsevier/CSPM JV)《Clinical e-Health》雜誌主編;
(2)美國《AJP-LUNG》雜誌副主編(IF=3.468);
(3)英國《International Journal of Chronic Obstructive Pulmonary Disease》雜誌副主編(IF=3.046);
(4)Journal of Proteomics –BIOINFO副主編(IF=3.929);
(5)美國《American Journal of Respiratory and Critical Care Medicine (AJRCCM)》雜誌編委(IF= 16.494);
(6)美國《CHEST》雜誌編委(IF=9.657);
(7)美國《American Journal of Respiratory Cell and Molecular Biology》雜誌編委(IF=4.109);
(8)美國《Cancer》雜誌編委(IF=6.072)。

獲獎榮譽


“為四化建設做出突出貢獻的中國博士學位獲得者“稱號,國家教委和國務院學位委員會
國家科學技術進步獎:“呼吸衰竭的發病機理與治療研究”,中華人民共和國國務院二等獎,第2完成人,2009。證書號:2009-J-233-2-01-R02
國家科學技術進步獎:“呼吸衰竭的發病機理與治療研究”,中華人民共和國國務院,二等獎,第3完成人,2009。證書號:2009-J-233-2-01-D03
中華醫學科技獎:“呼吸支持技術臨床應用研究”,中華醫學會,一等獎,第3完成人,2006。200601015U0303
第五屆中國科協期刊:“Inhibition of epedermal growth factor receptor expression by RNA interference in A549 cells”,中國科學技術協會,優秀學術論文獎,通訊作者,2007。
科技技進步獎:基於微流控晶元技術的肺癌個體化治療葯敏檢測平台構建及應用,教育部,二等獎,第三完成人,2015。2015-266
獲第四屆中國呼吸醫師獎,中國醫師協會,2009。
《現代呼吸病學》獲得第六屆中華優秀出版物(圖書)提名獎,中國出版協會,白春學,宋元林,蔡柏薔, 2016

學術成就


在科研上長期致力於“高科技含量、高創新內涵、高社會效益、高經濟價值”的創新和轉化醫學研究。建立二個創新實驗室:①物聯網醫學實驗室;②生物物理實驗室。先後獲得發明專利18項,實用新型專利26項,獲得國家自然科學基金重大、重點和面上等45項科研課題,發表論著550餘篇,SCI期刊論文170餘篇,總SCI影響因子累計1020餘分。主編《物聯網醫學》、《實用物聯網醫學》、《現代呼吸病學》、《物聯網醫學分級診療手冊》、《急性呼吸窘迫綜合征》、《早期肺癌》和《呼吸病診治綱要和質控要求》等專著10部。U-China Joint White Paper on the Internet of Things。
物聯網醫學:研發基於手機的無線感測肺功能儀(2009年美國胸科學會(ATS)會刊(ATS NEWS | VOL.35 NO.7/8)名人錄為此專題報道)並提出物聯網醫學,建立首個睡眠呼吸暫停物聯網醫學家庭管理平台。在2015年11月6日創立中國非公立醫療機構協會物聯網醫療專業委員會。在《實用物聯網醫學》一書中,大膽進行頂層設計,根據自己的學術沉澱,適宜技術和實戰經驗基礎,提出三級聯動的物聯網醫學架構,開展慢性氣道疾病、睡眠呼吸暫停和肺結節的診治實踐。在EU-China IoT Advisory Group中是中國唯一醫學專家,參編EU-China Joint White Pper on the Internet of Things(中國歐盟物聯網合作白皮書)。
肺癌早期診斷:提出將肺結節作為中國肺癌早期診斷突破口,創立物聯網醫學肺結節三加二式診斷法,計劃通過“百千萬工程”(“百”家醫院參與,培養“千”名專家;每年診治十“萬”例早期肺癌)利國利民。牽頭制定 “中國肺結節診治共識”,並作為主席、第一兼通訊作者用英文制定亞太國家和地區肺結節診治指南“CLINICAL PRACTICE GUIDELINES:Evaluation of pulmonary nodules: clinical practice guidelines in Asia”。

科研項目


(1)上海市臨床重點專科建設項目工作-爭創國家區域醫療中心的“強主體”類專科-呼吸病學科專業的學科帶頭人,於2018年5月17日勝利完成此次申報工作,經費1000萬,2018-2021。
(2)復旦大學附屬中山醫院臨床研究專項基金:聯合影像和腫瘤標誌物診斷早期肺癌的研究。經費100萬,2017-2019,項目批准號:2016ZSLC05。
(3)國家自然科學基金重大項目子課題項目: 生長因子幹細胞在肺損傷肺氣血屏障修復中的作用和機制;項目批准號:81490533,304萬元。
(4)上海市H7N9禽流感防治聯合攻關項目:物聯網醫學禽流感所致ARDS診治基地建設及實施,經費80萬,2013-2015。
(5)上海市重大疾病的臨床診治研究:慢性阻塞性肺疾病早期診斷和規範化干預的臨床研究,項目批准號:12411950100,經費400萬,2013-2015。
(6)上海市“重中之重”臨床重點學科呼吸內科項目:經費200萬,2013-2015。
(7)國家自然基金項目:“AQP3在氣道上皮屏障功能損傷修復中的作用及機制研究”,項目批准號:81170013,62萬元,01/2012-12/2014。
(8)China Medical Board (CMB)項目:“To promote tobacco control in the medical campus and affiliated hospitals of Fudan University through the platform of Shanghai Quality Control Center for Respiratory Diseases”, 項目批准號:China Medical Board Grant Number 09-960,$85,000, 01/2010 - 12/2011。
(9)國家自然基金委重點項目:“水通道蛋白1、5在肺泡-毛細血管屏障完整性中的作用及其對肺缺血再灌注損傷的影響”, 項目批准號: 30930090,175萬元,01/2010-12/2012。
(10)上海市科委項目:“血管內實時光纖血氣分析儀的研究”,項目批准號: 08441900200,80萬元,01/2009-01/2012。
(11)國家自然基金項目:“AQP5對高原肺水腫中細胞間連接的調節作用研究”,項目批准號:30871131,30萬元,01/2009-12/2011。
(12)上海市科委項目:“慢性阻塞性肺病診治技術研究”,項目批准號:074119507,40萬元,01/2008-12/2010。
(13)上海市醫學領軍人才:“急性呼吸窘迫綜合征診療新技術研究”,項目批准號:LJ06022,100萬元,01/2006-01/2009。
(14)國家自然科學基金:“水通道蛋白5對呼吸道粘液分泌的影響和調控機制研究”, 項目批准號:30370611,經費20萬元,2004-2007。
(15)上海市科技發展基金:“SARS血液凈化和氣體交換器”, 項目批准號:03DZ19619,經費20萬元,2003-2004。 

第一SCI內容


(1)Qunying Hong, Guoming Wu, Guisheng Qian, Chengping Hu,Jianying Zhou,Liangan Chen,Weimin Li,Jing Li,Xin Gong,Chunxue Bai. Prevention and managementof Lung Cancer in China. Cancer.2015,121:3080-3088(IF=5.649)
(2)Jing Li, Jian Zhou, Dan Zhang, Yuanlin Song, Jun She, and Chunxue Bai. Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischemia/reperfusion-induced lung injury. Journal of Cellular and Molecular Medicine. 2015.19(10):2341-2351. (IF=4.014)
(3)Niels H Chavannes1, Robert S Du Puy1 and Chunxue Bai. Suggestions for health information technology trials for respiratory disorders in low- and middle-income country settings: what can we learn from trials in high-income country settings? npj Primary Care Respiratory Medicine (2015) 25, 15045; doi:10.1038/npjpcrm.2015.45 (IF=1.447)
(4)Tang X, Bi J, Yang D, Chen S, Li Z, Chen C, Wang G, Ju M, Wang J, Wang Y, Gong R, Bai C, Zhou H, Jin X, Song Y. Emphysema is an independent risk factor for 5-year mortality in patients with bronchiectasis. Clin Respir J. 2015 (IF=2.147)
(5)Chunxue Bai, Chang-Min CHOI, Chung Ming CHU, Devanand ANANTHAM,James HO, Ali Zamir KHAN, Jang-Ming LEE, Shi Yue LI, Sawang SAENGHIRUNVATTANA, Anthony YIM. Evaluation of pulmonary nodules: clinical practice consensus guidelines for Asia. CHEST 2016; 150(4):877-893 (IF=6.136)
(6)Jie Liu, Zheng Li, Zilong Liu, Fen Zhu, Wenjing Li, Hong Jiang, Xiaodan Wu,Yuanlin Song, Shanqun Li, Chunxue Bai. Exhaled nitric oxide from the central airway and alveoli in OSAHS patients: the potential correlations and clinical Implications. Sleep Breath. 2016,20:145–154 (IF=2.482)
(7)Haiyan Ge, Huili Zhu, Nuo Xu, Dan Zhang, Jiaxian Ou, Guifang Wang, Xiaocong Fang, Jian Zhou, Yuanlin Song, Chunxue Bai. Increased lung ischemia-reperfusion injury in aquaporin 1 null mice is mediated via decreased HIF-2α stability. Am J Resp Cell Mol. 2016, 54(6):882-891. (IF:4.082)
(8)Lin Tong, Jian Zhou, Linyi Rong, Eric J. Seeley, Jue Pan1, Xiaodan Zhu, Jie Liu, Qin Wang, Xinjun Tang, Jieming Qu, Chunxue Bai & Yuanlin Song. Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury. Scientific RepoRts, 2016, 6:21642. DOI: 10.1038/srep21642 (IF= 5.228)
(9)Dan Zhang, Chichi Li, Jian Zhou, Yuanlin Song, Xiaocong Fang, Jiaxian Ou, Jing Li, and Chunxue Bai. Autophagy protects against ischemia/reperfusion- induced lung injury through alleviating blood–air barrier damage. J Heart Lung Transplant 2015;34:746–755 (IF= 7.509).
(10)Hai-Xing Zhu, Jie-Bai Zhou Xiao-Dan Zhu, Jian Zhou, Jing Li, Yuan-Lin Song, Chunxue Bai. Impaired self-healing capacity in airway epithelia lacking aquaporin-3. Respiratory Physiology & Neurobiology. 2016, 233:66-72. (IF=1.773)
(11)Nanshan Zhong, Hwa S. Moon, Kwan H. Lee, Aziah A. Mahayiddin,Watchara Boonsawat, Marie G.D. Isidro, Chunxue Bai, Achim Mueller,Norbert Metzdorf, Antonio Anzueto. TIOtropium Safety and Performance In Respimat (TIOSPIR): Analysis of Asian cohort of COPD patients. Respirology, July 2016, 21(8):1397-1403. (IF=3.078)
(12)Feng N, Wang Q, Zhou J, Li J, Wen X, Chen S, Zhu Z, Bai C, Song Y, Li H. Keratinocyte growth factor-2 inhibits bacterial infection with Pseudomonas aeruginosa pneumonia in a mouse model. J Infect Chemother. 2016, 22(1):44-52. (IF=1.452)
(13)Zhang Ziqiang, Zhou Nanjiang, Huang Jianguo, Ho Tsui-Ting, Zhu Zhuxian, Qiu Zhongmin, Zhou Xinchun, Bai Chunxue, Wu Fangting, Xu Min, Mo Yin-Yuan. Regulation of androgen receptor splice variant AR3 by PCGEM1. Oncotarget. 2016, 7(13):15481-15491. (IF=5.008)
(14)Wenxue Chen, Shaohua Lu, Jiaxian Ou, Guifang Wang, Yukun Zu, Fener Chen, Chunxue Bai. Metabonomic characteristics and biomarker research of human lung cancer tissues by HR1H NMR spectroscopy. Cancer Biomarkers. 2016, 16(4): 653-664. (IF=1.736)
(15)Chen C, Wang M, Zhu Z, Ou J, Xi X, Tang X, Lao X, Seeley E, Li T, Fan X, Du C, Wang Q, Yang L, Hu Y, Bai C, Zhang Z, Lu S, Song Y, Zhou W. Multiple gene mutations indentified in patients infected with influenza A (H7N9) virus. Sci Rep. 2016, 6:25614. (IF=5.228)
(16)Cook-Mills J, Gebretsadik T, Abdala-Valencia H, Green J, Larkin EK, Dupont WD, Shu XO, Gross M, Bai Chunxue, Gao YT, Hartman TJ, Rosas-Salazar C, Hartert T. Interaction of vitamin E isoforms on asthma and allergic airway disease. Thorax. 2016, 71(10):954-956. (IF=8.121)
(17)Yi Jia, Xu Fang, Xuehua Zhu, Chunxue Bai, Lei Zhu, Meiling Jin, Xiangdong Wang, Min Hu, Renhong Tang, Zhihong Chen. IL-13(+) Type 2 Innate Lymphoid Cells Correlate with Asthma Control Status and Treatment Response. American Journal of Respiratory Cell and Molecular Biology. 2016, 55(5):675-683. (IF=4.082)
(18)Gang Wang, Luyang Cao, Xiaowen Liu, Nathan A Sieracki, Anke Di, Xi Wen, Yong Chen, Shalina Taylor, Xiaojia Huang, Chinnaswamy Tiruppathi, You-Yang Zhao, Yuanlin Song, Xiaopei Gao, Tian Jin, Chunxue Bai, Asrar B Malik, Jingsong Xu. Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation. Developmental Cell. 2016, 38(5): 453-462. (IF=9.338)
(19)Dongni Hou, Tianlei Ying, Lili Wang, Cuicui Chen, Shuihua Lu, Qin Wang, Eric Seeley, Jianqing Xu, Xiuhong Xi, Tao Li, Jie Liu, Xinjun Tang, Zhiyong Zhang, Jian Zhou, Chunxue Bai, Chunlin Wang, Miranda Byrne-Steele, Jieming Qu, Jian Han, Yuanlin Song. Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients. Scientific Reports. 2016, 6:33843. (IF=5.228)
(20)Wenxue Chen, Shaohua Lu, Guifang Wang, Fener Chen, Chunxue Bai. Staging research of human lung cancer tissues by high-resolution magic angle spinning proton nuclear magnetic resonance spectroscopy (HRMAS(1)H NMR) and multivariate data analysis. Asia-Pacific Journal of Clinical Oncology. 2016. (IF=1.722)
(21)Shiming Wang, Xiao Song, Xiaoying Li, Xueying Zhao, Hongyan Chen, Jiucun Wang, Junjie Wu, Zhiqiang Gao, Ji Qian, Baohui Han, Chunxue Bai, Qiang Li & Daru Lu. RICTOR polymorphisms affect efficiency of platinum-based chemotherapy in Chinese non-small-cell lung cancer patients. Pharmacogenomics. 2016, 17(15):1637-1647. (IF=2.71)
(22)Dong Yang, Meiling Jin, Chunxue Bai, Jian Zhou, Yao Shen. Peroxiredoxin 6 suppresses Muc5ac overproduction in LPS-induced airway inflammation through H2O2-EGFR-MAPK signaling pathway. Respiratory Physiology & Neurobiology. 2017, 236:84-90. (IF=1.773)
(23)Yuanlin Song, Linlin Wang, Jian Wang, Chunxue Bai. Aquaporins in Respiratory System. Advances in Experimental Medicine and Biology. 2017, 969:115-122. (IF=1.953)
(24)Shujing Chen, Yutong Gu, Liping Qiao, Cuicui Wang, Yuanlin Song, Chunxue Bai, Yuchun Sun, Haiying Ji, Min Zhou, Hongli Wang, Renjie Chen, Haidong Kan. Fine particular constituents and lung dysfunction: A time-series panel study. Environmental Science & Technology. 2017, 51(3):1687-1694. (IF=5.393)
(25)Shujing Chen Changhui Wang Bing li guochao shi huiping li Jing Zhang Yutong gu Jian Zhou Yuanlin song Chunxue Bai.risk factors for FeV1 decline in mild COPD and high-risk populations. International Journal of COPD 2017:12 435–442 (IF= 3.046)
(26)Lian Wu, Jing Zhang, Jie Ming Qu, Chunxue Bai, Mervyn J Merrilees. Deposition of insoluble elastin by pulmonary fibroblasts from patients with COPD is increased by treatment with versican siRNA,International Journal of Chronic Obstructive Pulmonary Disease, 2017, 12:267—273, DOI https://doi.org/ 10.2147/COPD.S116217(IF= 3.046)
(27)Xixin Yan, Yuanlin Song,, Ce Shen wenbing Xu, Liangan Chen, Jian Zhang, Huiguo Liu, Mao Huang Guoxiang Lai, Guishen Qian, Jing wang, Xianwei Ye, Jinping Zheng, Chunxue Bai. Mucoactive and antioxidant medicines for COPD: consensus of a group of Chinese pulmonary physicians. International Journal of COPD 2017:12 803–812. (IF= 3.046)
(28)Dan Zhang, Chichi Li, Yuanlin Song, Jian Zhou, Yuping Li, Jing Li, Chunxue Bai. Integrin αvβ5 inhibition protects against ischemia/reperfusion-induced lung injury in an autophagy-dependent manner. Am J Physiol Lung Cell Mol Physiol. 2017, 313: 384-394. (IF=4.01)
(29)Yumin Zhou, Nan-shan Zhong, Xiaochen Li, Shuyun Chen, Jinping Zheng., Dongxing Zhao, Weimin Yao , Rongchang Zhi, Liping Wei, Bingwen He, Xiangyan Zhang, Changli Yang, Ying Li, Fenglei Li, Juan Du, Jianping Gui, Bin Hu, Chunxue Bai, Ping Huang, Gang Chen, Yongjian Xu, Changzheng Wang, Biao Liang, Yinhuan Li, Guoping Hu, Hui Tan, Xianwei Ye, Xitao Ma, Yan Chen, Xiwei Hu, Jia Tian, Xiaodan Zhu, Zhe Shi, Xiufang Du, Minjing Li, Shengming Liu, Ronghuan Yu, Jianping Zhao, Qianli Ma, Canmao Xie, Xiongbin Li, Tao Chen, Yingxiang Lin, Lizhen Zeng, Changxiu Ye, Weishu Ye, Xiangwen Luo, Lingshan Zeng, Shuqing Yu, Wei-jie Guan, and Pixin Ran. Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease. N Engl J Med 2017; 377:923-935. (IF= 72.406)
(30)Chunxue Bai, Masakazu Ichinose, Sang Haak Lee, Kwan Ho Lee, Olaf Jöns, Ulrich Bothner, Yihua Zhao, Roland Buhl. Lung function and long-term safety of tiotropium + olodaterol in East Asian patients with COPD. International Journal of COPD 2017: 12:3329–3339. (IF= 3.046)
(31)Vanbang Le, Dawei Yang, Yu Zhu, Bingbing Zheng, Chunxue Bai, Quocthinh Nguyen, and Hongcheng Shi. Automated Classification of Pulmonary Nodules for Lung Adenocarcinomas Risk Evaluation: An Effective CT Analysis by Clustering Density Distribution Algorithm. J. Med. Imaging Health Inf. 2017, 7(8):1753-1758 (IF= 0.621).
(32)Chen Wang, Jianying Xu, Lan Yang, Yongjian Xu, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen,Kewu Huang, Wanzhen Yao, Tieying Sun, Guangliang Shan, Ting Yang, Yingxiang Lin, Sinan Wu, Jianguo Zhu, Ruiying Wang,Zhihong Shi, Jianping Zhao, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Liren Ding, Ting Yang§, Yahong Chen, Yanfei Guo, Fei Xiao,Yong Lu, Xiaoxia Peng, Biao Zhang, Dan Xiao, Chung-Shiuan Chen, Zuomin Wang, Hong Zhang, Xiaoning Bu, Xiaolei Zhang, Li An, Shu Zhang,Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Bin Cao, Huaping Dai, Lirong Liang, Jiang He†, for the China Pulmonary Health Study Group.Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study):a national cross-sectional study. The Lancet. 2018, 391(10131): 1706-1717. (IF=47.83)
(33)Chen Bao, Xiaocen Wang, Yuan Ji, Chen Xu, Dong Yang, Chunxue Bai. Clinical and pathological characteristics of pulmonary mucosa-associated lymphoid tissue lymphoma: a case report. Int J Clin Exp Med. 2017, 10(4): 7231-7235. (IF=1.17)
(34)Jian Wang, Jianan Huang, Linlin Wang, CuiCui Chen, Dong Yang, Meiling Jin, Chunxue Bai, Yuanlin Song. Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-kB signaling pathway. J Thorac Dis 2017, 9(11): 4398-4412. (IF=2.365)
(35)Fanglei Liu, Chunxue Bai, Zhongliang Guo. The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism. Oncotarget, 2017, 8(41): 70084-70096. (IF=4.73)
(36)Haixing Zhu, Lin Shi, Yong Zhang, Yichun Zhu, Chunxue Bai, Xiangdong Wang, Jiebai Zhou. Myocyte enhancer factor 2D provides a cross‑talk between chronic inflammation and lung cancer. Journal of translational medicine. 2017, 15:65-74. (IF=3.93)
(37)Xun Wang, Xiaojing An, Xiaocen Wang, Chen Bao, Jing Li, Dong Yang, Chunxue Bai. Curcumin ameliorated ventilator-induced lung injury in rats. Biomedicine & Pharmacotherapy. 2018, 98: 754-761. (IF=2.42)
(38)Chunxue Bai. Letter from China. Respirology 2018,23:718– 719 . (IF=3.256)
(39)NUO XU, XUEHUA CHEN, SHENGDI WU, MAOSONG YE, MEILING ZHANG, LIN TONG, XIAODAN ZHU, JIE LIU, FEIFEI HU and Chunxue Bai. Chronic pulmonary complications associated with toxic epidermal necrolysis: A case report and literature review. EXPERIMENTAL AND THERAPEUTIC MEDICINE 2018,16: 2027-2031(IF=1.41)
(40)GE ZHANG, TAO FANG2, MEIJIA CHANG1, JING LI, QUNYING HONG, Chunxue Bai, and JIAN ZHOU. Calpain 2 knockdown promotes cell apoptosis and restores gefitinib sensitivity through epidermal growth factor receptor/protein kinase B/survivin signaling. ONCOLOGY REPORTS 2018: 1937-1946. (IF= 2.976)
(41)Shaohua Lu, Hui Kong, Yingyong Hou, Di Ge, Wei Huang, Jiaxian Ou, Dawei Yang, Li Zhang, Guoming Wu, Yong Song, Xiaoju Zhang, Changwen Zhai, Qun Wang, Hongguang Zhu, Ying Wu, Chunxue Bai. Two plasma microRNA panels for diagnosis and subtype discrimination of lung cancer. Luan cancer. 2018, 123, 44-51. (IF=4.468)
(42)Jian Zhou, Meijia Chang, Jing Li, Tao Fang, Jie Hu, Chunxue Bai. Knockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest. Respiratory research. 2018, 19:96. (IF=3.841)
(43)Meijia Chang, Jie Hu, Tao Fang, Jing Li, Yuanlin Song, Jian Zhou, Chunxue Bai. PLIN2 confers gefitinib resistance by inhibiting cell apoptosis via activation of EGFR/AKT/survivin in PC9R cells. ONCOTARGET. 2018. (IF=4.65)
(44)Jian Zhou, KL Kwak, Z Wu, D Yang, J Li, M Chang, Y Song, H Zeng, LJ Lee, J Hu, C Bai. PLAUR Confers Resistance to Gefitinib Through EGFR/P-AKT/Survivin Signaling Pathway. Cell Physiol Biochem. 2018,47(5):1909-1924. (IF= 4.83)
(45)Dawei Yang, Xiaoju Zhang, Charles A. Powell, Jun Ni, Bin Wang, Jianya Zhang, Yafei Zhang, Lijie Wang, Zhihong Xu, Li Zhang, Guoming Wu, Yong Song, Wenhua Tian, Jia-an Hu, Yong Zhang, Jie Hu, Qunying Hong, Yuanlin Song, Jian Zhou, and Chunxue Bai. Probability of Cancer in High-Risk Patients Predicted by the Protein-Based Lung Cancer Biomarker Panel in China: LCBP Study. Cancer 2018;124:262-70(IF= 6.072).
(46)Jun Yin, Chunxue Bai. Pharmacotherapy for Adult Patients with Acute Respiratory Distress Syndrome. Chinese Medical Journal, 2018, 131(10):1138-1041(IF=1.064).
(47)Linlin Wang, Meng Shi, Lin Tong, Jian Wang, Shimeng Ji, Jing Bi, Cuicui Chen, Jinjun Jiang, Chunxue Bai, Jian Zhou, and Yuanlin Song. Lung-Resident Mesenchymal Stem Cells Promote Repair of LPS-Induced Acute Lung Injury via Regulating the Balance of Regulatory T cells and Th17 cells. Inflammation. 2019. 42(1):199-210. (IF=2.92)
(48)Jian Zhou; Guimei Qu; Ge Zhang; Zuoren Wu; Jing Liu; Dawei Yang; Jing Li; Meijia Chang; Hengshan Zeng; Jie Hu; Tao Fang; Yuanlin Song; Chunxue Bai. Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway.Journal of Experimental & Clinical Cancer Research. 2019, (IF= 6.217).
(49)Wang B.Q., Shi M., Zhang J.P., Wu X., Chang M.J., Chen Z.H., Shen H.H., Song Y.L., Zhou J, Bai C.X. (2018a) Knockdown of Tfpi-Anchored Endothelial Cells Exacerbates Lipopolysaccharide-Induced Acute Lung Injury via NF-κB Signaling Pathway. Shock. 2019 ;51(2):235-246. (IF=2.75)
(50)Yuanlin Song, Chunxue Bai. XueBiJing Injection versus Placebo for Critically Ill Patients with Severe Community-Acquired Pneumonia: A Randomized Controlled Trial,Critical Care Medicine, 2019,Volume 47 - Issue 9 - p e735-e743v(IF=6.63)

著作譯作


(1)Michael A. Matthay, Collen Horan, Chunxue Bai, and Yibing Wang. Alceolar epithelialfluid transport under normal pathological conditions. P71-85, in acute respiratory distress syndrome, Edited by Matalon and Sznajder, Plenum Press, New York, 1998
(2)Christoph Thuemmler and Chunxue Bai Editor-in-chief: e-Health 4.0:How Virtualization and Big Data are Revolutionizing Healthcare,Springer,2016
(3)Yuanlin Song, Linlin Wang, Jian Wang, and Chunxue Bai, Aquaporins in Respiratory System. P115-123, in Aqaporins, Edited by Baoxue Yang, Springer,2017.
(4)白春學 李為民 陳良安. 主編 《早期肺癌》. 人民衛生出版社,北京 2018(80萬字)
(5)白春學,宋元林,胡成平.主編:上海交通大學出版社“精準醫學出版工程·精準醫學基礎系列”圖書呼吸系統疾病的精準預防、診斷與治療,上海 (90萬字)待出版
(6)白春學 趙建龍. 主編 《物聯網醫學》. 科學出版社,北京 2016(73萬字)

科普宣傳


(1)白春學. 主編《高原旅遊和飛機旅行保健百問》. 第二軍醫大學出版社,上海,2006.
(2)白春學. 主編《牽手健康去旅行》. 上海文化出版社,上海,2013.
(3)物聯網臨床試驗的春天到了-喜聞美國國會公布法案意將真實世界研究取代傳統臨床試驗。
(4)特發性肺纖維化藥物治療選擇與長期管理策略。