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鄧明華

北京大學數學科學學院教授

鄧明華,漢族,男,北京大學數學科學學院教授。

人物經歷


時間所在機構擔任職務
99年秋-01年春99級二班班主任班主任
98年-01年數學模型競賽組織
04年秋-07年春04級碩士二班班主任班主任

主講課程


開課時間課程名稱授課對象
98,99,00年春數學模型習題該院三年級本科生
98年秋,00春數學分析習題計算機系99,98
00年春線性代數社會學98
00年秋高等數學C生命學院醫預00
99年秋高等數學B城環、地質99
03年秋生物信息中的數學模型與方法全校通選(本、研)
04年春數學模型本系01級
08年秋非參數統計本研合上(30人)
08年秋非參數統計該院本研合上
08年秋非參數統計該院本研合上
04年秋生物信息中的數學模型與方法研究生
05年春數學模型該院02級本科生
05年秋數學模型該院03級本科生
06年春數學模型該院04級本科生
06年秋非參數統計該院本研合上
07年春數學模型該院05級本科生
07年秋非參數統計該院本研合上
08年春數學模型該院06級本科生

主要貢獻


主要論著

作品名稱下載鏈接
1. 楊群峰,鄧明華,表示張量積與量子對稱,數學進展,24:532-539, 1995.
2. Minghua Deng, Minping Qian, Segmentation of Connected Image Based on Phase-locking. Communications in Nonlinear Science & Numerical Simulation. Vol.1, No.3, pp.32-36, 1996.
3. Qian, M.P. and Deng, M. The Exploratory Statistics and Neural Networks. Proc. 3rd Asia Statistics Conference, 1998.
4. 鄧明華,錢敏平,基於隱馬氏模型(HMM)的手寫體漢字識別方法及其實現。第三屆中國計算機智能介面與智能應用學術會議論文集,204-208, 1997.
5. 朱學慶,錢敏平,鄧明華,數據融合在手寫體漢字識別中的應用。第四屆中國計算機智能介面與智能應用學術會議論文集,23-27, 1998.
6. Feng Qi, Minghua Deng, Minping Qian, Xueqing Zhu. A Novel Algorithm for Handwritten Chinese Character Recognition. Proceedings of Third International Conference:Advances in Multimodal Interfaces (ICMI 2000), Beijing, China, October 2000, 379-385.
7. Deng, M., Mehta, S., Sun, F. and Chen, T. Inferring domain-domain interactions from protein-protein interactions. Genome Research 12: 1540-1548, 2002. See also The ACM-SIGACT 6th Annual International Conference on Computational Molecular Biology (RECOMB02), 95-103, 2002.
8. Zhang, K., Deng, M., Chen, T., Waterman, M.S. and Sun, F. A dynamic programming approach for haplotype partitioning. The Proceeding of National Academy of Sciences (PNAS), 99(11): 7335-9, May 28 2002.
9. Deng, M., Sun, F. and Chen, T. Assessment of the reliability of protein-protein interactions and protein function prediction. Pacific Symposium on Biocomputing(PSB2003). 140-151, 2003.
10. Deng, M., Zhang, K., Mehta, S., Chen, T. and Sun F. Prediction of protein function using protein-protein interaction data. Journal of Computational Biology 10: 947-960, 2003. See also Proceeding of IEEE Computer Society Bioinformatics Conference (ISCB2002), 197-206, 2002.
11. Lanckriet,G.R.G, Deng, M., Cristianini, N. Jordan, M.I. and Noble, W.S. Kernel-based data fusion and its application to protein function prediction in yeast. Pac. Symp. Biocomputing(PSB2004), 300-311, 2004.
12. Deng, M., Tu, Z., Chen, T. and Sun, F. Mapping Gene Ontology to proteins based on protein-protein interaction data, Bioinformatics, 20: 895-902, 2004.
13. Deng, M., Chen, T. and Sun F. An integrative analysis of protein function prediction. Journal of Computational Biology 11: 463-475, 2004. See also The ACM-SIGACT 7th Annual International Conference on Computational Molecular Biology (RECOMB03), 95-103, 2003.
14. Feng Xiucheng, Qian Minping, Deng Minghua, Ma Xiaotu, Yan Xiting. Application of hidden semi-Markov model to 3-prime splice sites identification. Progress in Biochemistry and Biophysics, 31(5), 455-458, 2004.
15. Xiting Yan, Minghua Deng, Wing K. Fung, Minping Qian. Detecting differentially expressed genes by relative entropy. Journal of Theoretical Biology 234: 395-402, 2005
16. 馬盡文,鄧明華。生物醫學信息處理-DNA微陣列數據在醫學中的應用。物理 34(5): 371-380, 2005
17. Huan Yu, Minping Qian and Minghua Deng. Understanding protein-protein interactions: from domain level to motif Level. Proceeding of Sino-Germany conference: Network, from biology to theory 247-263, 2005.
18. Xiucheng Feng, Lin Wan, Minghua Deng, Fengzhu Sun and Minping Qian. An efficient algorithm for deciphering regulatory motifs. Proceeding of Sino-Germany conference: Network, from biology to theory 265-285, 2005.
19. Huan Yu and Minghua Deng. ClustalY: Speed up the guide tree building for ClustalW. Proceeding of Eighth international conference on high-performance computing in Asia-Pacific region. 608-610. Nov.30-Dec.3, 2005. Beijing.
20. Lee H, Tu Z, Deng M, Sun F and Chen T. Diffusion kernel based logistic regression models for protein function prediction. OMICS: Integrative Biology.10(1):40-55, 2006.
21. Lee H, Deng M, Sun F and Chen T. Inferring domain-domain interactions from multiple biological data sources. BMC Bioinformatics.25;7(1):269, 2006.
22. Yuping Zhang, Minping Qian, Qi Ouyang, Minghua Deng, Fangting Liand Chao Tang. Stochastic model of yeast cell-cycle network. Physica D 219:35-39, 2006.
23. Huan Yu, Minping Qian and Minghua Deng. Using a stochastic Adaboost algorithm to discover interactome motif pairs from sequence. Computational Intelligence and Bioinformatics.International Conference on Intelligent Computing, ICIC 2006, Kunming, China, August 16-19, 2006. Proceedings, Part III.622-630, 2006.
24. Yuping Zhang, Huan Yu, Minghua Deng and Minping Qian. Nonequilibrium Model for Yeast Cell Cycle. Computational Intelligence and Bioinformatics. International Conference on Intelligent Computing, ICIC 2006, Kunming, China, August 16-19, 2006. Proceedings, Part III, 786-791, 2006.
25. 楊良懷, 呂丕明, 陳立軍,鄧明華。k-gram方法識別MicroRNA前體。生物化學生物物理進展 34(2): 154-161, 2007.
26. 談效俊, 張永新, 錢敏平, 張幼怡,鄧明華. 晶元數據標準化方法比較. 生物化學與生物物理進展 34(6):625-633,2007.
27. Lourdes Pena-Castillo, Murat Tasan, Chad L Myers, Hyunju Lee, Trupti Joshi, Chao Zhang, Yuanfang Guan, Michele Leone, Andrea Pagnani, Wan Kyu Kim, Chase Krumpelman, Weidong Tian, Guillaume Obozinski, Yanjun Qi, Sara Mostafavi, Guan Ning Lin, Gabriel F Berriz, Francis D Gibbons, Gert Lanckriet, Jian Qiu, Charles Grant, Zafer Barutcuoglu, David P Hill, DavidWarde-Farley, Chris Grouios, Debajyoti Ray, Judith A Blake, Minghua Deng, Michael I Jordan, William S Noble, Quaid Morris, Judith Klein-Seetharaman, Ziv Bar-Joseph, Ting Chen, Fengzhu Sun, Olga G Troyanskaya, Edward M Marcotte, Dong Xu, Timothy R Hughes and Frederick P Roth. A critical assessment of Mus musculus gene function prediction using integrated genomic evidence. Genome Biology 9:S2, 2008.
28. Lin Wan, Wenjiang J. Fu, Minghua Deng and Minping Qian. A Method to Correct Systematic Bias in Affymetrix SNP Arrays. Proceedings of the 2008 International Conference on BioMedical Engineering and Informatics, BMEI 2008, May 28-30, 2008, Sanya, Hainan, China - Volume 1, 442-446.
29. Wenjiang J. Fu, Ming Li, Lin Wan, Minghua Deng, Minping Qian. On Design of Oligonucleotide SNP Arrays and Methods for Genotype Calling. Proceedings of the 2008 International Conference on BioMedical Engineering and Informatics, BMEI 2008, May 28-30, 2008, Sanya, Hainan, China - Volume 1, 453-458.
39.Fugui Wang, Lin Hou, Jiangfeng Xu, Minping Qian, Minghua Deng. A robust empirical Bayesian method for detecting differentially expressed genes. Proceedings of the 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009, Oct 17-19, 2009, Tianjin, China - Volume 4, 1824-1828.
38.Wei Wei, Lin Wan, Minping Qian, Minghua Deng. The Implementation and Application of the Microarray Preprocessing Generalized PDNN Model. Proceedings of the 2nd International Conference on BioMedical Engineering and Informatics, BMEI 2009, Oct 17-19, 2009, Tianjin, China - Volume 3, 1536-1540, 2009.
30. Lin Wan, Dayong Li, Donglei Zhang, Xue Liu, Wenjiang J. Fu, Lihuang Zhu, Minghua Deng, Fengzhu Sun and Minping Qian. Conservation and Implications of Eukaryote Transcriptional Regulatory Regions across Multiple Species. BMC Genomics 9:623, 2008.
31. Hao Zheng, Xingyi Hang, Ji Zhu, Minping Qian, Wubin Qu, Chenggang Zhang, Minghua Deng. REMAS: a new regression model to identify alternative splicing events from exon array data. BMC Bioinformatics 10 (Suppl 1):S18, 2009. APBC2009 Best Paper Award.
32. Quan Wang, Lin Wan, Dayong Li, Lihuang Zhu, Minping Qian, Minghua Deng. Searching for bidirectional promoters in Arabidopsis thaliana. BMC Bioinformatics 10 (Suppl 1): S29, 2009.
33. Shaojin Duan, Lin Wan, Wenjiang J. Fu, Hong Pan, Qi Ding, Chang Chen, Peiwei Han, Xiaoyan Zhu, Liying Du, Hongxiao Liu, Yuxia Chen, Ximing Liu, Xiting Yan, Minghua Deng and Minping Qian. Nonlinear cooperation of p53-ING1-induced bax expression and protein S-nitrosylation in GSNO-induced thymocyte apoptosis: A quantitative approach with cross-platform validation. Apoptosis 14(2):236-245, 2009.
34. 韓放, 吳晶辰, 徐江峰, 鄧明華. 利用PLS-VIP方法篩選差異表達基因. 北京大學學報 45(1):1-5, 2009.
35. 侯琳, 錢敏平, 朱雲平, 鄧明華. 轉錄因子結合位點生物信息學研究進展. 遺傳 31(4): 365-373, 2009.
37.Hao Zheng, Fugui Wang, Jiangfeng Xu, Nengfeng Zhou, Minping Qian, Ji Zhu and Minghua Deng. Pathway Detection Based on Hierarchical LASSO Regression Model. Proceedings of the 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009, Oct 17-19, 2009, Tianjin, China - Volume 4, 1893-1899, 2009.
36. Hang, X., Li, P., Li, Z., Qu, W., Yu, Y., Li, H., Shen, Z., Zheng, H., Gao, Y.,Wu, Y.,Deng, M., Sun, Z., Zhang, C.Transcription and splicing regulation in human umbilical vein endothelial cells under hypoxic stress conditions by exon array. BMC Genomics 10:126,2009.

科研項目

起止時間項目名稱資助來源
2003.1-2005.12基因組註釋系統的標準建立和軟體開發863生物(陳良標)
2003.1-2005.12複雜系統的統計力學研究及在計算分子生物學中的應用基金委面上(錢敏平)
2003.1-2005.12真核生物基因及其編碼蛋白的信息基礎基金委重大(錢敏平)
2004.1-2008.12基因功能預測的生物信息學理論與應用(子課題三)973(來魯華-錢敏平)
2006.1-2008.12轉錄因子結合位點(TSBS)研究基金委面上(鄧明華)
2007.1-2008.12構建基於生物學功能的跨物種轉錄組比較和進化研究的平台863生物(陳良標)
2009.1-2011.12基於探針雜交機制的生物晶元數據預處理統計方法研究基金委面上(鄧明華)
2008.1-2010.12蛋白質複雜網路構建與分析及其在肝癌疾病中的應用863生物(鄧明華)
2009.1-2013.12基於蛋白質結構與相互作用的計算生物學研究(子課題:蛋白質相互作用網路形成的結構基礎與動力學分析)973(蔣華良-劉瑩)

獲獎記錄


獲獎時間所獲獎勵
1999年優秀主幹基礎課及教學優秀獎(高等數學B,鄭志明