張志凌
武漢大學化學與分子科學學院教授
張志凌,1974年12月出生,武漢大學化學與分子科學學院博士,現任武漢大學化學與分子科學學院博士生導師、教授。
1997年7月于吉林大學化學系獲學士學位,
2002年11月於武漢大學化學與分子科學學院獲博士學位。
2001年7月提前留校工作,
2003年10月赴法國巴黎高等師範學校(ENS)進行一年的博士后工作,
2005年晉陞副教授,
2008年破格晉陞教授。
當前主要從事微流控晶元,生物電分析和納米生物醫學感測等方面的研究。湖北省儀器儀錶協會常務理事。國家基金委“新型生物醫學探針技術基礎及應用”創新研究群體及教育部“化學生物學應用基礎研究”創新團隊骨幹成員。
微流控晶元,生物電分析,納米生物醫學感測
1. 國家自然科學基金面上項目(20875072)“集成化細胞分析微流控晶元研製”
2. 國家自然科學基金青年基金(20305011)“DNA與蛋白質相互作用的表面分析化學研究”
3. 國家科技部863專題課題(2006AA03Z320)“高靈敏快速診斷用熒光-磁性-生物靶向三功能納米球的研發”
4. 教育部留學回國人員科研啟動基金(教外司留[2005]383號)“微流控晶元通道表面生物功能化及生化分析中的應用”
1. 國家自然科學基金創新研究群體項目(20621502)“新型生物醫學探針技術基礎及應用”
2. 國家科技部973項目“微流控學在化學和生物醫學中的應用基礎研究”子課題(2007CB714507) “傳染性疾病診斷微流控新方法及其應用研究”
3. 國家科技部國家重大科學研究計劃項目(s973)“病毒與細胞相互作用的熒光納米實時檢測新技術及動態過程可視化”課題(2006CB933101)“基於熒光納米材料標記的病原體檢測新技術”
4. 國家自然科學基金重大項目“微流控生物化學分析系統的基礎研究”子課題(20299034)“微流控系統中的細胞操縱及其生化組分分析方法研究”
5. 國家科技攻關計劃“生物納米與醫藥”國家納米科技重大專項課題(2003BA310A22)“新型納米生物醫用材料-多功能量子點的研發”(副組長)
6. 教育部創新團隊發展計劃(教技函[2006]8號IRT0543)“化學生物學應用基礎”
分析化學(化院本科生,藥學院本科生)
1. Zhi-Ling Zhang, Dai-Wen Pang*, Rong-Ying Zhang, Jia-Wei Yan, Bing-Wei Mao, Yi-Peng Qi. Investigation of DNA Orientation on Gold by EC-STM. Bioconjugate Chem. 13(1) (2002)104-109. (影響因子3.766)
2. Zhi-Ling Zhang, C. Crozatier, M. Le Berre, Yong Chen, In-Situ Bio-functionalization and Cell Adhesion in Microfluidic Devices. Micro and Nano Engineering International Conference (2004) 40-41.
3. Zhi-Ling Zhang, Dai-Wen Pang*, Hong Yuan, Ru-Xiu Cai, Héctor D. Abruña. Electrochemical DNA Sensing Based on Gold Nanoparticle Amplification. Analytical and Bioanalytical Chemistry 381 (2005) 833–838. (影響因子2.098)
4. Yuan-Hai Zhu, Zhi-Ling Zhang*, Dai-Wen Pang, Electrochemical oxidation of theophylline at multi-wall carbon nanotube modified glassy carbon electrode. J. Electroanal. Chem. 581 (2005) 303-309. (影響因子2.228,通訊作者)
5. Zhi-Ling Zhang, C. Crozatier, M. Le Berre, Yong Chen, In-Situ Bio-functionalization and Cell Adhesion in Microfluidic Devices. Microelectronic Engineering 78-79 (2005) 556-562.
6. Rong-Ying Zhang, Dai-Wen Pang*, Zhi-Ling Zhang, Jia-Wei Yan, Jian-Lin Yao, Zhong-QunTian, Bing-Wei Mao, Shi-Gang Sun. Investigation of Ordered ds-DNA Monolayers on Gold Electrodes. J. Phys. Chem. B, 106(43)(2002)11233-11239. (影響因子3.843)
7. Ye-Fu Wang, Dai-Wen Pang*, Zhi-Ling Zhang, Hu-Zhi Zheng, Jun-Ping Cao, Jun-Tao Shen. Visual Gene Diagnosis of HBV and HCV Based on Nanoparticle Probe Amplification and Silver Staining Enhancement. Journal of Medical Virology, 70(2)(2003)205-211.
8. Zhe-Xue Lu, Lei Zhou, Zhi-Ling Zhang, Wan-Liang Shi, Zhi-Xiong Xie, Hai-Yan Xie, Dai-Wen Pang*, Ping Shen. Cell damage induced by photocatalysis of TiO2 thin films. Langmuir, 19(21)(2003)8765-8768. (影響因子3.295)
9. Hui-Hong Liu, Zhi-Quan Tian, Zhe-Xue Lu, Zhi-Ling Zhang, Min Zhang, Dai-Wen Pang*. Direct Electrochemistry and Electrocatalysis of Heme-proteins Entrapped in Agarose Hydrogel Films. Biosensors & Bioelectronics, 20(2)(2004)294-304. (影響因子3.251)
10. Jing-Xue Shi, Xian-En Zhang, Wei-Hong Xie, Ya-Feng Zhou, Zhi-Ping Zhang, Jiao-Yu Deng, Anthony E. G. Cass, Zhi-Ling Zhang, Dai-Wen Pang, Cheng-Gang Zhang. Improvement of Homogeneity of Analytical Biodevices by Gene Manipulation. Anal. Chem. 76 (3) (2004) 632-638. (影響因子5.450)
11. Guo-Ping Wang, Er-Qun Song, Hai-Yan Xie, Zhi-Ling Zhang, Zhi-Quan Tian, Chao Zuo, Dai-Wen Pang*, Dao-Cheng Wu and Yun-Bo Shi. Biofunctionalization of fluorescent-magnetic-bifunctional nanospheres and their applications. Chem. Commun. (34) (2005) 4276-4278. (影響因子3.997)
12. Min Xie, Hui-Hui Liu, Ping Chen, Zhi-Ling Zhang, Xiao-Hui Wang, Zhi-Xiong Xie, Yu-Min Du, Bo-Qun Pan, Dai-Wen Pang*. CdSe/ZnS-labeled carboxymethyl chitosan as a bioprobe for live cell imaging. Chem. Commun.(2005) 5518-5520. (影響因子3.997)
13. Sheng-Fu Wang,Ting Chen, Zhi-Ling Zhang, Xin-Cheng Shen, Zhe-Xue Lu, Dai-Wen Pang*, Kwok-Yin Wong. Direct Electrochemistry and Electrocatalysis of Heme Proteins Entrapped in Agarose Hydrogel Films in Room-Temperature Ionic Liquids. Langmuir 21(2005) 9260-9266. (影響因子3.295)
14. Hai-Yan Xie, Jian-Gong Liang, Yi Liu, Zhi-Ling Zhang, Dai-Wen Pang*, Zhi-Ke He, Zhe-Xue Lu, Wei-Hua Huang. Preparation and Characterization of Overcoated II-VI Quantum Dots. Journal of Nanoscience and Nanotechnology, 5(6) (2005) 880-886.
15. Hai-Yan Xie, Chao Zuo, Yi Liu, Zhi-Ling Zhang, Dai-Wen Pang*, Xiao-Lan Li, Jian-Ping Gong, Calum Dickinson, Wuzong Zhou, Cell-targeting Multifunctional Nanospheres with both Fluorescence and Magnetism. Small, 1 (2005) 506-509.
16. Hu-Zhi Zheng, Hui-Hui Liu, Shao-Xing Chen, Zhe-Xue Lu, Zhi-Ling Zhang, Dai-Wen Pang*, Zhi-Xiong Xie*, Ping Shen. Yeast transformation process studied by fluorescence labeling technique. Bioconjugate Chem. 16(2) (2005) 250-254.(影響因子3.766)
17. Zhe-Xue Lu, Zhi-Ling Zhang, Ming-Xi Zhang, Hai-Yan Xie, Zhi-Quan Tian, Ping Chen, Hua Huang, Dai-Wen Pang*. Core/shell Quantum Dots-photosensitized Nano-TiO2 Films: Fabrication and Application to the Damage of Cells and DNA. J. Phys. Chem. B, 109 (2005) 22663-22666.
已申請專利:
1. 龐代文, 王業富,張志凌,曹軍平,蔡汝秀, 鄭鵠志. 發明專利: 納米微粒標記基因探針及其製備方法和應用. 專利號: ZL 01 1 33527.0, 證書號: 第154129 號, 專利申請日: 2001.9.30., 授權公告日: 2004.5.5.
3. 龐代文, 劉毅, 張志凌. 發明專利: 一種油溶性量子點水溶性化的方法. 申請號: 00410013332.x, 申請日期: 2004.6.22.
4. 龐代文, 魯哲學, 張志凌. 發明專利: 量子點納米二氧化鈦複合膜的製備方法。申請號: 200510018188.3, 申請日期: 2005.1.24.
6. 龐代文, 謝敏, 張志凌, 杜予民. 發明專利: 一種糖生物功能化的水溶性量子點的製備方法-研磨法. 申請號: 200510018233.5, 申請日期: 2005.2.1.
8. Dai-Wen Pang,Hai-Yan Xie,Guo-Ping,Wang,Zhi-Ling Zhang,Er-Qun Song,Yun-Bo Shi. Tri-functional nanospheres. US Patent, Application No. 11/335,380, Application date: May 24, 2005.