周慧君

周慧君博士，本科畢業於武漢大學後繼赴美留學，在康奈爾大學獲得了分子生物和遺傳學博士，並在斯坦福大學完成了臨床分子基因學的博士后研究。最終獲得了美國醫學遺傳學會（American Board of Medical Genetics）資歷認證的臨床分子遺傳學家和美國醫學遺傳學協會(American College of Medical Genetics）會員的認證，是國際僅有的323位美國醫學遺傳學會（ABMG）臨床分子遺傳學行醫執照認證專家，這對於在美留學並成為公認的基因學界的科學家可以說是一難得的成就，在華人科學家領域內也是鮮見的。

通過基因實現個性化醫療是生物遺傳學的一個新領域，周慧君博士從事這個領域的工業、科研工作已經超過14年。周慧君博士於1998-2002年領導了Incyte Genomics公司的生物遺傳學計劃，作為該公司藥物遺傳學的帶頭人，她幫助製藥公司開展了包括臨床藥物試驗設計在內的藥物研發和服務工作。此後周慧君博士在矽谷公司DNA Direct擔任資深總監。DNA Direct主要提供DNA檢測和網上醫學遺傳學服務，推廣以個人基因圖譜為指導的醫療服務，以幫助預防疾病，提高生活品質，並實現個性化治療。

2008年年底，周慧君博士率核心團隊回國創業，在北京正式創建了iDNA網(益基生物科技)，成為國內首家網際網路基因信息服務平台，同時受邀加入了亞傑商會，並正式成為全球華人生物基因學界的頂級協會-百花協會北京分會會長。在歸國之前，iDNA網的核心生物基因技術與商業模式在08年初即獲得了全美生物醫藥商務計劃評比第一名，09年在歸國后即榮獲了創新中國項目展示北京區第二名。並與中國疾病控制中心合作開展了包括北京、武漢、成都、青島、杭州、哈爾濱及昆明七個城市的基因與健康的研究項目。2009年參與了科技部國家科技平台重大專項課題研究。

“讓每一個中國人更懂自己”是iDNA網的使命，也是創始人周慧君博士的夢想。調查顯示：iDNA網的會員近五成是通過口碑相傳得知iDNA網並使用基因信息產品；每天來自全國各地不同行業，不同背景，不同健康狀況的用戶通過iDNA網科學健康地預知了自己未來的生命疾病風險，從而提前進行了醫學、飲食、健康作息等干預，高速有效的提升了生命質量，精準、科學、健康的把握住了自己生命的未來。

中文論文

[1]保元湯合真武湯聯合常規西藥治療慢性心衰的臨床觀察[J].張秋,尹小星,周慧君.光明中醫.2016(16)

[2]中西醫結合治療充血性心衰56例臨床觀察[J].林楠,尹小星,周慧君.實用中醫內科雜誌.2011(04)

[3]溫陽益氣湯治療慢性充血性心力衰竭臨床研究[J].周慧君,尹小星,牛永軍.遼寧中醫雜誌.2010(05)

[4]增率湯治療病態竇房結綜合征臨床研究[J].周慧君,尹小星,林楠.遼寧中醫雜誌.2010(03)

[5]新絡合劑治療不穩定性心絞痛的臨床研究[J].周慧君,尹小星,曲燕.光明中醫.2010(01)

[6]增率湯治療病態竇房結綜合征的臨床觀察[J].黃健,周慧君,陳岩.遼寧中醫雜誌.2007(05)

[7]中西醫結合治療充血性心力衰竭的臨床觀察[J].周慧君,黃健.遼寧中醫雜誌.2004(10)

英文論文

[1]A Knowledge-Based Decision Framework for Merchandise Systemic Risk Management Under Cross-Broader E-Commerce Pattern[J]. He Junliang,Yan Wei,Huang Youfang,Tan Caimao,Zhou Huijun. Advances in Transdisciplinary Engineering.

[2]Application of the Modality of Multiple Disciplinary Team for a Perioperative Patient with Suspected Novel Coronavirus Pneumonia and Cervical Spine Fracture in Nursing[J]. Chen Yuanli,Zhang Yingying,Zhou Huijun,Li Wenzhen,Hao Ruiting,Peng Liang. International Journal of Clinical Medicine. 2020(12)

[3]Infection Prevention Strategy in General Hospital under Regular Epidemic Prevention and Control[J]. Chen Yuanli,Xue Ying,Zhang Yingying,Zhou Huijun,Peng Liang. Open Journal of Preventive Medicine. 2021(04)

[4]Eomes Impedes Durable Response to Tumor Immunotherapy by Inhibiting Stemness, Tissue Residency, and Promoting the Dysfunctional State of Intratumoral CD8+ T Cells

[J]. Sun Runzi,Wu Yixian,Zhou Huijun,Wu Yanshi,Yang Zhongzhou,Gu Yanzheng,Jiang Jingting,Lu Binfeng,Zhu Yibei. Frontiers in Cell and Developmental Biology.

[5]PD-1 Blockade Combined with IL-33 Enhances the Antitumor Immune Response in a Type-1 Lymphocyte-mediated Manner[J]. He Honghong,Shi Liyan,Meng Dan,Zhou Huijun,Ma Jingshu,Wu Yixian,Wu Yanshi,Gu Yanzheng,Xie Wei,Zhang Jing,Zhu Yibei. Cancer Treatment and Research Communications. 2021(prepublish)

[6]Imaging and therapeutic efficacy of "Cu -labeled melanin nanoparticles in A431 tumor -bearing nude mouse models[J]. Zhou Huijun,Li Lin,Cheng Zhen. JOURNAL OF NUCLEAR MEDICINE.

[7]Cost-effectiveness analysis of glecaprevir/pibrentasvir regimen for treating Chinese patients with chronic hepatitis C genotype 1 and genotype 2 infection.[J]. Zhou HuiJun,Wu Gang,Li JiMing,Naidoo Nasheen,Xie YanXiang,Feng BoLan,Wang Pei,Luo JiWei. Annals of palliative medicine.

[8]Decision and Coordination of Cross-Border E-Commerce Supply Chain: Based on Four Modes of Cooperation[J]. Yan Wei,Zhou Huijun,Li Hui. SCIENTIFIC PROGRAMMING.

[9]Development and validation of a prognostic nomogram for predicting early recurrence after curative resection of stage II/III gastric cancer.[J]. Ma Min,Xiao Haifan,Li Liang,Yin Xianli,Zhou Huijun,Quan Hu,Ouyang Yongzhong,Huang Gang,Li Xiaorong,Xiao Hua. World journal of surgical oncology. 2019(1)

[10]Development and validation of a prognostic nomogram for predicting post-operative pulmonary infection in gastric cancer patients following radical gastrectomy.[J]. Xiao Haifan,Zhou Huijun,Liu Ke,Liao Xianzhen,Yan Shipeng,Yin Bin,Ouyang Yongzhong,Xiao Hua. Scientific reports. 2019(1)

[11]Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image-Guided Surgery via NIR-II Fluorescence and PET Bimodal Imaging.[J]. Zhang Qing,Zhou Huijun,Chen Hao,Zhang Xiao,He Shuqing,Ma Lina,Qu Chunrong,Fang Wei,Han Yanjiang,Wang Da,Huang Yuanjian,Sun Yueming,Fan Quli,Chen Yue,Cheng Zhen. Small （Weinheim an der Bergstrasse, Germany）. 2019(45)

[12]The effect of preoperative smoking cessation and smoking dose on postoperative complications following radical gastrectomy for gastric cancer: a retrospective study of 2469 patients.[J]. Quan Hu,Ouyang Linda,Zhou Huijun,Ouyang Yongzhong,Xiao Hua. World journal of surgical oncology. 2019(1)

[13]Teaching Evaluation of Modern Chinese History Courses for Different Majors[J]. Huijun Zhou. History Research. 2019(2)

[14]Imaging and therapeutic efficacy of 64Cu-labeled melanin nanoparticles in A431 tumor-bearing nude mouse models[J]. Huijun Zhou,Lin Li,Zhen Cheng. The Journal of Nuclear Medicine.

[15]The significant effect of photo-catalyzed redox reactions on the immobilization of chromium by hematite[J]. Liu Jing,Zhu Runliang,Chen Qingze,Zhou Huijun,Liang Xiaoliang,Ma Lingya,Parker Steve C.. Chemical Geology.

[16]TiO 2 /Schwertmannite nanocomposites as superior co-catalysts in heterogeneous photo-Fenton process[J]. Yanping Zhu,Chun Zeng,Runliang Zhu,Yin Xu,Xingyan Wang,Huijun Zhou,Jianxi Zhu,Hongping He. Journal of Environmental Sciences.

[17]Effects of charge density on the hydration of siloxane surface of montmorillonite: A molecular dynamics simulation study[J]. Wei Shen,Lin Li,Huijun Zhou,Qing Zhou,Meng Chen,Jianxi Zhu. Applied Clay Science.

[18]Visible-light Ag/AgBr/ferrihydrite catalyst with enhanced heterogeneous photo-Fenton reactivity via electron transfer from Ag/AgBr to ferrihydrite[J]. Yanping Zhu,Runliang Zhu,Lixia Yan,Haoyang Fu,Yunfei Xi,Huijun Zhou,Gangqiang Zhu,Jianxi Zhu,Hongping He. Applied Catalysis B: Environmental.

[19]Hot deformation behaviour and Hansel-Spittel constitutive model of Cr5 alloy for heavy backup roll[J]. Xuewen Chen,Nana Wang,Xiang Ma,Huijun Zhou. Int. J. of Computational Materials Science and Surface Engineering. 2018(3/4)

[20]Unusual Uptake of 131I in a Cutaneous Benign Fibrous Histiocytoma in a Patient With Thyroid Cancer[J]. Huijun Zhou,Jiaqi Yan,Rui Huang,Lin Li. Clinical Nuclear Medicine. 2018(1)

[21]NF-κB-induced WIP1 expression promotes colorectal cancer cell proliferation through mTOR signaling[J]. Fei Bai,Huijun Zhou,Zhongping Fu,Jiangbo Xie,Yingbin Hu,Shaolin Nie. Biomedicine & Pharmacotherapy.

[22]Molecular Simulation Study on the Interaction of Nanoparticles With Clay Minerals: C60 on Surfaces of Pyrophyllite and Kaolinite[J]. Zhou Huijun,Chen Meng,Zhu Lifang,Li Lin,Zhu Runliang,He Hongping. Clays and Clay Minerals. 2017(6)

[23]In vitro and in vivo evaluation of cationic liposomes containing zoledronic acid as anticancer agent[J]. Xinjun Cai,Zeng Wang,Congyao Wang,Huijun Zhou,Jianjun Ni,Yingying Xu,Liyan Zhu,Tianhong Fu,Fanzhu Li,Sangsang Chen,Jianshe Zhou. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016(2)

[24]Effects of adding bulking agent, inorganic nutrient and microbial inocula on biopile treatment for oil-field drilling waste[J]. Jie Ma,Yongqi Yang,Xiaoli Dai,Yetong Chen,Hanmei Deng,Huijun Zhou,Shaohui Guo,Guangxu Yan. Chemosphere.

[25]Biodistribution and evaluation of 131 I-labeled neuropilin-binding peptide for targeted tumor imaging.[J]. Dong Ping,Cai Huawei,Chen Lihong,Li Yalun,Yuan Cen,Wu Xiaoai,Shen Guohua,Zhou Huijun,Zhang Wenjie,Li Lin. Contrast media & molecular imaging. 2016(6)

[26]^sup 18^F-FDG PET/CT for the Diagnosis of Residual or Recurrent Nasopharyngeal Carcinoma After Radiotherapy: A Metaanalysis[J]. Huijun Zhou,Guohua Shen,Wenjie Zhang,Huawei Cai,Yue Zhou,Lin Li. The Journal of Nuclear Medicine. 2016(3)

[27]Diagnostic performance of diffusion-weighted magnetic resonance imaging for detection of pelvic metastatic lymph nodes in patients with cervical cancer: A systematic review and meta-analysis.[J]. Shen Guohua,Zhou Huijun,Jia Zhiyun,Deng Houfu. The British journal of radiology.

[28]Machinability of Hastelloy C-276 using Hot-pressed sintered Ti（C7N3）-based cermet cutting tools[J]. Kaitao Xu,Bin Zou,Chuanzhen Huang,Yang Yao,Huijun Zhou,Zhanqiang Liu. Chinese Journal of Mechanical Engineering. 2015(3)

[29]Tool damage and machined-surface quality using hot-pressed sintering Ti（C7N3）/WC/TaC cermet cutting inserts for high-speed turning stainless steels[J]. Bin Zou,Huijun Zhou,Chuanzhen Huang,Kaitao Xu,Jun Wang. The International Journal of Advanced Manufacturing Technology. 2015(1-4)

[30]Formation of birefringence patterns under everyday conditions[J]. Youtian Zhang,Lan Chen,Sihui Wang,Huijun Zhou. European Journal of Physics. 2014(5)

[31]Study of a hot-pressed sintering preparation of Ti（C 7 N 3 ）-based composite cermets materials and their performance as cutting tools[J]. Bin Zou,Huijun Zhou,Kaitao Xu,Chuanzhen Huang,Jun Wang,Shasha Li. Journal of Alloys and Compounds.

[32]Effects of sintering processes on the mechanical properties and microstructure of Ti（C,N）-based cermet cutting tool materials[J]. Huijun Zhou,Chuanzhen Huang,Bin Zou,Hanlian Liu,Hongtao Zhu,Peng Yao,Jun Wang. International Journal of Refractory Metals and Hard Materials.

[33]GW25-e0396 Progression of carotid atherosclerosis and associated risk factors in elderly Chinese population[J]. Song Canluo,Zhao Chunhua,Nasheen Naidoo,Zhou Huijun,Tong Haiyan. Journal of the American College of Cardiology. 2014(16)

[34]Effects of metal phases and carbides on the microstructure and mechanical properties of Ti（C,N）-based cermets cutting tool materials[J]. Huijun Zhou,Chuanzhen Huang,Bin Zou,Hanlian Liu,Hongtao Zhu,Peng Yao,Jun Wang. Materials Science & Engineering A.

[35]Angiopoietin-like protein 2 negatively regulated by microRNA-25 contributes to the malignant progression of colorectal cancer.[J]. Zhou Jumei,Wang Jing,Wu Shengqi,Zhu Suyu,Wang Sai,Zhou Huijun,Tian Xiaoqing,Tang Ning,Nie Shaolin. International journal of molecular medicine. 2014(5)

[36]Unraveling the mystery of the “Maoshan Bugle”[J]. Xu Chen,Ming Qin,Sihui Wang,Huijun Zhou. American Journal of Physics. 2014(2)

[37]Incidence and Clinical Features of Calreticulin mutation in Patients with Jak2V617F-Negative Essential Thrombocytosis and Primary Myelofibrosis from Singapore[J]. Ng Chin Hin,Ng Christopher W.S,Fan Bingwen Eugene,Ong Kiat Hoe,Seah Elaine,Zhou Huijun,Koay Siew Chuan Evelyn,Chng Wee Joo. Blood. 2014(21)

[38]Coupling between clay swelling/collapse and cationic partition[J]. Huijun Zhou,Meng Chen,Runliang Zhu,Xiancai Lu,Jianxi Zhu,Hongping He. Geochimica et Cosmochimica Acta.

[39]Association between interleukin-36γ and tumor progression in non-small cell lung cancer.[J]. Liu Lin,He Honghong,Xu Dan,Feng Yuehua,Zhou Huijun,Shi Liyan,Gu Yanzheng,Wang Jian,Zhu Yibei. Oncology letters. 2020(3)

[40]Closest-Packing Water Monolayer Stably Intercalated in Phyllosilicate Minerals under High Pressure.[J]. Chen Meng,Zhou Huijun,Zhu Runliang,Lu Xiancai,He Hongping. Langmuir : the ACS journal of surfaces and colloids. 2020(2)

[41]Expression and clinical significance of CD74 and MMP-9 in colon adenocarcinomas.[J]. Ruan Peng,Gu Yangchun,Zhou Huijun,Zhang Wen,Wang Dingxue,Liang Jinglin,Li Cong. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 2020(2)

[42]Pressure-temperature diagram of wetting and dewetting in a hydrophobic grain boundary and the liquidlike to icelike transition of monolayer water[J]. Meng Chen,Huijun Zhou,Runliang Zhu,Hongping He. Physical Review B. 2020(16)

[43]64 Cu-labeled melanin nanoparticles for PET/CT and radionuclide therapy of tumor[J]. Huijun Zhou,Qing Zhang,Yan Cheng,Lili Xiang,Guohua Shen,Xiaoai Wu,Huawei Cai,Daifeng Li,Hua Zhu,Ruiping Zhang,Lin Li,Zhen Cheng. Nanomedicine: Nanotechnology, Biology, and Medicine. 2020(prepublish)

[44]Association among the prognostic nutritional index, completion of adjuvant chemotherapy, and cancer-specific survival after curative resection of stage II/III gastric cancer.[J]. Xiao Hua,Zhou Huijun,Zhang Peng,Xiao Haifan,Liu Ke,Chen Xiaoyan,Quan Hu,Yin Bin,Li Rongrong,Huang Gang,Yin Xianli,Ouyang Yongzhong. European journal of clinical nutrition. 2020(4)

[45]Health status and associated factors of HIV-infected patients in Kunming, China.[J]. Li Jing,Wu Chao,Suo Chen,Zhou Huijun,Lu Tian,Lu Lin,Assanangkornchai Sawitri,Chongsuvivatwong Virasakdi,McNeil Edward B,Qiao Chunhong,Wang Jiaping,Wang Pei,Li Yan. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 2020(prepublish)

[46]The Role and Mechanism of S1PR5 in Colon Cancer.[J]. Zhou Huijun,Yin Xianli,Bai Fei,Liu Wu,Jiang Shaofeng,Zhao Jinfeng. Cancer management and research. 2020(default)

[47]Biodegradable 131 Iodine-Labeled Microspheres: Potential Transarterial Radioembolization Biomaterial for Primary Hepatocellular Carcinoma Treatment.[J]. Pang Fuwen,Li Yuhao,Zhang Wenjie,Xia Chunchao,He Qing,Li Zhenlin,Xiao Liu,Song Simin,Dong Ping,Zhou Huijun,Shao Tuo,Cai Huawei,Li Lin. Advanced healthcare materials. 2020(13)

[48]Health utility of type 2 diabetes patients using basal insulin in China: results from the BEYOND II study[J]. Chaoyun Li,HuiJun Zhou,Pei Wang. Acta Diabetologica. 2020(prepublish)

[49]Possible influence of delta-aminolevulinic acid dehydratase polymorphism and susceptibility to renal toxicity of lead: a study of a Vietnamese population.[J]. Chia Sin Eng,Zhou Huijun,Tham Mei Theng,Yap Eric,Dong Nguyen-Viet,Tu Nguyenthi Hong,Chia Kee Seng. Environmental health perspectives. 2005(10)

[50]La possession inaliénable en chinois mandarin et en français[J]. Marie-Thérèse Vinet,Huijun Zhou. Cahiers de Linguistique Asie Orientale. 2003(2)

[51]Possibilities of newer ALAD polymorphism influencing human susceptibility to effects of inorganic lead on the neurobehavioral functions[J]. Sin-Eng Chia,Zhou Huijun,Tham Mei Theng,Eric Yap. Neurotoxicology. 2006(2)

[52]Penetrating Keratoplasty in Asian Eyes[J]. Donald T.H. Tan,Prathiba Janardhanan,Huijun Zhou,Yiong-Huak Chan,Hla Myint Htoon,Leonard P.K. Ang,Laurence S. Lim. Ophthalmology. 2007(6)

[53]Possibilities of newer ALAD polymorphism influencing human susceptibility to effects of inorganic lead on the neurobehavioral functions.[J]. Chia Sin-Eng,Huijun Zhou,Theng Tham Mei,Yap Eric. Neurotoxicology. 2007(2)

[54]Penetrating keratoplasty in Asian eyes: the Singapore Corneal Transplant Study.[J]. Tan Donald T H,Janardhanan Prathiba,Zhou Huijun,Chan Yiong-Huak,Htoon Hla Myint,Ang Leonard P K,Lim Laurence S. Ophthalmology. 2008(6)

[55]Experimental study on correlation between sound velocity and solute molecular weight in polyethylene glycol solution[J]. XiangYu Yin,Hao Song,HuiJun Zhou. Science in China Series G: Physics, Mechanics and Astronomy. 2009(1)

1998年，獲得 美國McCormick科學家獎

2001年，獲得Incyte發明創新獎

2007年4月12日，《自然》雜誌刊登周慧君博士的報道

2008年，獲得Morgan Lewis企業家獎

2008年，iDNA網商業模式獲得全美生物醫藥商務計劃評比第一名

2009年，iDNA網獲得創新中國項目展示北京第二名

美國醫學遺傳學會（American Board of Medical Genetics）資歷認證的臨床分子遺傳學家

美國醫學遺傳學協會(American College of Medical Genetics）資深委員

“人類變異基因工程”（Human Variome）成員

《舊金山紀事報》譽為“二十一世紀國際都市青年領袖人物的典範”