鄭成超

山東農業大學生命科學學院院長

鄭成超 男,1962年1月生,山東臨朐人。博士,教授,博士生導師,長江學者創新團隊負責人。現任山東農業大學生命科學學院院長。

人物履歷


1982年畢業於山東農業大學
先後獲山東農業大學農學碩士和中國農業大學理學博士學位;
1989年2月至6月赴丹麥哥本哈根研修種子技術;
1992年1月至1996年1月赴美國加利福尼亞大學戴維斯分校植物生物學系留學,主要從事植物分子生物學方面的研究;
2001年作為教育部選派的高級訪問學者赴美國北卡羅萊納大學合作研究,主要進行了轉基因表達調控的研究。

任免信息


2018年6月24日,中國共產黨山東省第十一屆委員會第五次全體會議通過,決定遞補十一屆省委候補委員鄭成超同志為十一屆省委委員。

學術兼職


山東生物化學與分子生物學學會副理事長
植物學報》編委

所獲榮譽


2004年入選國家“新世紀百千萬人才工程”國家級人才;
2007年入選 教育部“長江學者創新團隊”帶頭人;
泰山學者特聘教授
2008年入選 有突出貢獻的中青年專家;
1996年,獲山東省“青春立功”一等功
山東省新長征突擊手稱號。

科研項目


主持承擔了國家“ 863”、國家“ 973”、國家轉基因植物研究專項、國家自然科學基金、教育部博士點科研基金等多項課題。
鄭成超
鄭成超
1、國家轉基因植物研究專項《植物葉片高效特異表達啟動子及 表達載體的研製》;
2、國家“863”計劃項目《棉花耐鹽基因的分離、功能鑒定與應用》;
3、國家“973”計劃項目《作物應答高鹽、低溫脅迫的分子調控機理》;
4、國家自然科學基金《PNZIP基因的生物學功能鑒定與分析》;
5、國家自然科學基金《擬南芥轉錄因子AT103突變體分離及其功能研究》;
6、國家自然科學基金《一個新型棉花CCCH鋅指轉錄因子的功能鑒定與分析》;
7、教育部“長江學者創新團隊發展計劃”《作物高產優質的生理與分子基礎》2007-2009;
8、國家轉基因專項《作物抗除草劑抗逆基因克隆》1998-2003;
9、國家自然科學基金《擬南芥miRNA169家族及靶基因的功能鑒定與分析》2010-2013

申請專利


在重要功能基因、特異啟動子克隆與功能鑒定等方面均獲得了許多擁有我國自主知識產權的研究成果,申請專利8項

註冊基因


克隆並在GenBank註冊基因36個。

教學工作


主講
本科生《Gene cloning and DNA analysis》、《基因工程實驗》;
碩士生《生物化學與分子生物學專業英語》;
博士生《生物化學與分子生物學專題討論》;
招收生物學博士后。

研究方向


1.植物重要功能基因的克隆、鑒定與利用:以重要農作物小麥玉米棉花、煙草以及模式植物擬南芥為研究材料,克隆與作物發育、抗逆性等密切相關的功能基因,探討這些基因的表達模式及其調控機制,研究其在作物遺傳改良上的利用價值,獲得擁有我國自己專利或知識產權的基因,為生物技術育種提供基因資源。
2.基因表達調控元件的鑒定與應用:人為控制外源基因在轉基因作物的特定器官、特定時期表達,必須依靠組織專一型啟動子、發育誘導型啟動子和其它基因表到調控元件。本方向主要研究各類啟動子的表達調控機制和應用,染色質重塑與基因表達,核基質結合序列MAR(matrix attachment region)對轉基因表達的調控機制與應用。

主要論文


在《 Molecular Cell》(影響因子14.178)、《 Neuclear Acids Research》、《 Plant Physiology》、《 New Phytologist》、《 中國科學》、《 科學通報》等國內外著名學術刊物上發表論文170多篇。
1、Zheng CC, Porat R, Lu P, O’Neill SD. PNZIP is a novel mesophyll-specific cDNA that is regulated by phytochrome and a circadian rhythm and encodes a protein with a leucine zipper motif. Plant Physiology, 1998, 116:27~35
2、Zheng CC, Bui AQ, O’Neill SD. Abundance of an mRNA encoding a HMG DNA-binding protein is regulated by light and an endogenous rhythm. Plant Molecular Biology. 1993, 23:813~823
3、張可偉,鄭成超(通訊作者)。強MAR的分離及體外功能鑒定。科學通報,2002,47(20):1572- 1577
4、楊宇濤,鄭成超(通訊作者)。一個光合組織特異表達強啟動子的分離及功能分析。中國科學,2003,33(4):298-306.
5、李宏,鄭成超(通訊作者)。6個植物MARs序列的ARS功能鑒定與分析。科學通報,2003,48(24):2544- 2548
6、Ning Liu, Cheng-Chao Zheng(通訊作者), NTZIP antisense plants show reduced chlorophyll levels, Plant Physiology and Biochemistry. 2004,42(4):321-327
7、Changai Wu, Zheng Chengchao(通訊作者). The cotton GhNHX1 gene encoding a novel putative tonoplast Na+/H+ antiporter plays an important role in salt stress. Plant and Cell Physiology, 2004,45(5): 489-496
8、Hai-Yan Li, Cheng-Chao Zheng(通訊作者). Colonization by the Arbuscular Mycorrhizal Fungus Glomus versiforme Induces a Defense Response Against the Root-knot Nematode Meloidogyne incognita in the Grapevine (Vitis amurensis Rupr.), Which Includes Transcriptional Activation of the Class III Chitinase Gene VCH3. Plant and Cell Physiology, 2006, 47(1): 154–163
9、Xiao Wang, Chengchao Zheng(通訊作者). Isolation and purification of honokiol and magnolol from cortex magnoliae officinalis by high-speed counter-current chromatography. Journal of chromatography A. 2004, 1036(2):171-175.
10、Xiao Wang, Chengchao Zheng(通訊作者) An efficient new method for extraction, separation and purification of psoralen and isopsoralen from Fructus Psoraleae by supercritical fluid extraction and high-speed counter-current chromatography。Journal of chromatography A. 2004,.1055:135-140
11、Xiao Wang, Chengchao Zheng(通訊作者). Application of preparative high-speed counter-current chromatography for separation and purification of arctiin from Fructus Arctii, Journal of chromatography A. 2004, 1063: 247-251
12、Hua Xue, Cheng-Chao Zheng(通訊作者), TM2, a novel strong matrix attachment region isolated from tobacco, increases transgene expression in transgenic rice calli and plants. Theoretical and Applied Genetics. 2005, 110:620-627
13、Hongxin Zhang and Cheng-Chao Zheng(通訊作者).Expression and characterization of Helicobacter pylori heat-shock protein A (HspA) protein in transgenic tobacco (Nicotiana tabacum) plants. Biotechnology and Appllied Biochemistry. 2006,43, 33–38
14、 Da-Peng Shan, Jin-Guang Huang, Yu-Tao Yang, Ying-Hui Guo and Cheng-Chao Zheng*. Cotton GhDREB1 increases plant tolerance to low temperature and is negatively regulated by gibberellic acid. New Phytologist2007. 176: 70–81
15、Meng-Meng Zhanga, Lu-Sha Ji, Hua Xue, Yu-Tao Yang, Chang-Ai Wu and Cheng-Chao Zheng*. High transformation frequency of tobacco and rice via Agrobacterium-mediated gene transfer by flanking a tobacco matrix attachment region Physiologia Plantarum2007.129: 644–651.
16、Dong Wang, Yinghui Guo, Changai Wu, Guodong Yang, Yingying Li and Chengchao Zheng*. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics2008, 9:44
17、Hanhua Liu, Xin Tian, Yanjie Li, Changai Wu and Chengchao Zheng*.Microarray-based analysis of stress-regulated microRNAs in Arabidopsis thaliana. RNA2008, 14: 836-843
18、 Xin Huang · Wei Zhu · Silan Dai · Shupeng Gai ·Guosheng Zheng · Chengchao Zheng*. The involvement of mitochondrial phosphate transporter in accelerating bud dormancy release during chilling treatment of tree peony (Paeonia suVruticosa). Planta2008, 228(4):545-52
19、Xiyan Yu, Xiufeng Wang, Wenqian Zhang, Tingting Qian, Guimin Tang, Yankui Guo, Chengchao Zheng*. Antisense Suppression of an Acid Invertase Gene (MAI1) in Muskmelon Alters Plant Growth and Fruit Development. Journal of Experimental Botany.2008, 59(11):2969-77.
20、Jiedao Zhang, Longtao Lu, Lusha Ji, Guodong Yang, Chengchao Zheng*. Functional characterization of a tobacco matrix attachment region-mediated enhancement of transgene expression. Transgenic Research.2009, 18:377-385
21、 Hongxin Zhang and Cheng-Chao Zheng* Oral immunogenicity and protective efficacy in mice of a carrot-derived vaccine candidate expressing UreB subunit againstHelicobacter pylori.Protein Expression and Purification. 2009, 69:127-131
22、Tongtong Xue, Xinzheng Li, Wei Zhu, Changai Wu, Guodong Yang, and Chengchao Zheng*. Cotton metallothionein GhMT3a, a reactive oxygen species scavenger, increased tolerance against abiotic stress in transgenic tobacco and yeast. Journal of Experimental Botany.2009, 60: 339-349
23、 Ying-Hui Guo, Yue-Ping Yu, Dong Wang, Chang-Ai Wu, Guo-Dong Yang, Jin-Guang Huang and Cheng-Chao Zheng*. GhZFP1, a novel CCCH-type zinc finger protein from cotton, enhances salt stress tolerance and fungal disease resistance in transgenic tobacco by interacting with GZIRD21A and GZIPR5. New Phytologist2009, 183: 62–75
24、Yu-Tao Yang, Yan-Li Yu, Guo-Dong Yang, Jie-Dao Zhang and Cheng-Chao Zheng*, Tissue-specific expression of the PNZIP promoter is mediated by combinatorial interaction of different cis-elements and a novel ranscriptional factor. Nucleic Acids Research2009, 37(8):2630–2644
25、Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu and Cheng-Chao Zheng*.GhDREB1enhances abiotic stress tolerance, delays GA-mediated development and represses cytokinin signaling in transgenic Arabidopsis. Plant, Cell & Environment, 2009, 32, 1132–1145
26、YanLi Yu, YanZe Li, LingLi Li, JinXing Lin, ChengChao Zheng*Overexpression ofPwTUA1, a pollen-specific tubulin gene, increases pollen tube elongation by altering the distribution of α-tubulin and promoting vesicle transport. Journal of Experimental Botany,2009, 60(9):2737-49
27、 Yanjie Li, Yaru Fu, Lusha Ji, Changai Wu, Chengchao Zheng*.Characterization and expression analysis of the Arabidopsis mir169 family. Plant Science2010,178: 271-280
28、Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu, Cheng-Chao Zheng*.Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis. Gene.2010, 451:38-44
29、Dongmei Xi, Wushuang Liu, Guodong Yang, Changai Wu, Cheng-chao Zheng*. Seed-specific overexpression of antioxidant genes in Arabidopsis enhances oxidative stress tolerance during germination and early seedling growth. Plant Biotechnology Journal,2010, 8:796-806.
30、 Hao Huan, Sheng-Dong Qi, Fang Qi, Chang-Ai Wu, Guo-Dong Yang and Cheng-Chao Zheng*. NtKTI1, a Kunitz trypsin inhibitor with antifungal activity from Nicotiana tabacum, plays an important role in tobacco’s defense response. FEBS Journal2010, 277:4076-4088 .
31、Yanjie Li, Yaru Fu, Jinguang Huang, Changai Wu and Chengchao Zheng*Insight into the transcriptional regulation during the early development of the maize brace root. FEBS Journal2010