餘四斌

博士生導師

餘四斌,男,1967年9月出生,教授,農學博士,博士生導師。

工作經歷


1990年以來一直主要從事水稻遺傳育種和分子生物學研究以及教學工作,講授數量遺傳學、種子生理工藝學和遺傳學進展等課程。
1998-2000年在國際水稻研究所IRRI)進行合作研究。
目前研究方向主要包括水稻新種質創建、基因多樣性分析與優異基因發掘、分子育種、種子質量控制等。講授數量遺傳學、種子生理工藝學和遺傳學進展等課程。

個人作品


學術論文

1. Zhang CP, Wang DW, Wang J, Sun Q, Tian L, Tang X, Yuan Z, He H*, Yu S*. Genetic dissection and validation of chromosomal regions for transmission ratio distortion in intersubspecific crosses of rice. Front Plant Sci (2020) 11:563548. Doi: 10.3389/fpls.2020.563548
2. Yu S#, Ali J#, Zhang CP, Li ZK*, Zhang Q*. Genomic breeding of green super rice varieties and their deployment in Asia and Africa. Theor Appl Genet (2020) 133:1427–1442
3. Zhang CP, Yuan ZY, Wang YT, Sun WQ, Tang X, Sun YJ , Yu S*. Genetic dissection of seed dormancy in rice (Oryza sativa L.) by using two mapping populations derived from common parents. Rice (2020) 13: 52
4. Yuan S, Wang YT, Zhang CP, He H*, Yu S*. Genetic dissection of seed dormancy using chromosome segment substitution lines in rice (Oryza sativa L.). Int J Mol Sci (2020) 21: 1344
5. Gao DW, Sun WQ, Wang DW, Dong HL, Zhang R, Yu S*. A xylan glucuronosyltransferase gene exhibits pleiotropic efects on cellular composition and leaf development in rice. Sci Reports (2020) 10: 3726
6. Wang P#, Xiong Y#, Gong R, Yang Y, Fan Kai, Yu S*. A key variant in the cis-regulatory element of flowering gene Ghd8 associated with cold tolerance in rice. Sci Reports (2019) 9:9603
7. Wang P, Gong R, Yang Y, Yu S*. Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7. BMC Plant Biology (2019) 19:462
8. Yuan Z, Fan K, Xia L, Ding X, Tian L, Sun W, He H, Yu S*. Genetic dissection of seed storability and validation of candidate gene associated with antioxidant capability in rice (Oryza sativa L.). Int J Mol Sci (2019) 20: 4442
9. Tang X, Gong R, Sun W, Zhang C, Yu S*. Genetic dissection and validation of candidate genes for flag leaf size in rice (Oryza sativa L.). Theor Appl Genet (2018) 131: 801-815
10. Gong R, Cao HS, Zhang J, Xie K, Wang DW, Yu S*. Divergent functions of the GAGA-binding transcription factor family in rice. The Plant J (2018) 94: 32-47
11. Chen J#, Wang JL#, Chen W, Sun WQ, Peng M, Yuan ZY, Shen SQ, Xie K, Jin C, Sun YY, Liu XQ, Fernie AR, Yu S*, Luo J*. Metabolome analysis of multi-connected biparental chromosome segment substitution line populations. Plant Physiology (2018) 178:612-625
12. Sun W, Gao D, Xiong Y, Tang X, Xiao X, Wang C, Yu S*. Hairy Leaf 6, an AP2/ERF transcription factor, interacts with OsWOX3B and regulates trichome formation in rice. Mol Plant (2017) 10: 1417–1433
13. Zhang J, Chen LL, Xing F, Kudrna DA, Yao W, Copetti D, Mu T, Li W, Song JM, Xie W, Lee S, Talag J, Shao L, An Y, Zhang CL, Ouyang Y, Sun S, Jiao WB, Lv F, Du B, Luo M, Maldonado CE, Goicoechea JL, Xiong L, Wu C, Xing Y, Zhou DX, Yu S, Zhao Y, Wang G, Yu Y, Luo Y, Zhou ZW, Hurtado BE, Danowitz A, Wing RA, Zhang Q*. Extensive sequence divergence between the reference genomes of two elite indica rice varieties Zhenshan 97 and Minghui 63. Proc Natl Acad Sci USA. (2016) 113(35): E5163–71
14. Zhang HW, Fan YY, Zhu YJ, Chen JY, Yu S, Zhuang J*. Dissection of the qTGW1.1 region into two tightly-linked minor QTLs having stable effects for grain weight in rice. BMC Genetics (2016)17: 98
15. Wang X, Li L, Yang Z, Zheng X, Yu S, Xu C, Hu Z. Predicting rice hybrid performance using univariate and multivariate GBLUP models based on North Carolina mating design II. Heredity (2016) 1–9
16. Sun W, Zhou Q, Yao Y, Qiu X, Xie K, Yu S*. Identification of genomic regions and the isoamylase gene for reduced grain chalkiness in rice. PLoS ONE (2015) 10: e0122013. doi:10.1371/journal.pone.0122013
17. Xie W, Wang G, Yuan M, Yao W, Lyu K, Zhao H, Yang M, Li P, Zhang X, Yuan J, Wang Q, Liu F, Dong H, Zhang L, Li X, Meng X, Zhang W, Xiong L, He Y, Wang S, Yu S, Xu C, Luo J, Li X, Xiao J, Lian X, Zhang Q*. Breeding signatures of rice improvement revealed by a genomic variation map from a large germplasm collection. Proc Natl Acad Sci USA (2015) 112(39): E5411–5419
18. Wang Q, Xie W, Xing H, Yan J, Meng X, Li X, Fu X, Xu J, Lian X, Yu S, Xing Y, Wang G*. Genetic architecture of natural variation in rice chlorophyll content revealed by a genome-wide association study. Mol Plant (2015) 8:946–57
19. Wu J, Feng F, Lian X, Teng X, Wei H, Yu H, Xie W, Yan M, Fan P, Li Y, Ma X, Liu H, Yu S, Wang G, Zhou F, Luo L, Mei H*. Genome-wide Association Study (GWAS) of mesocotyl elongation based on re-sequencing approach in rice. BMC Plant Biol (2015) 15:218
20. Chen W, Gao Y, Xie W, Gong L, Lu K, Wang W, Li Y, Liu X, Zhang H, Dong H, Zhang W, Zhang L, Yu S, Wang G, Lian X, Luo J*. Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism. Nat Genet (2014) 46 (7): 714 –721
21. Gong L, Chen W, Gao Y, Liu X, Zhang H, Xu C, Yu S, Zhang Q, Luo J*. Genetic analysis of the metabolome exemplified using a rice population. Proc Natl Acad Sci (2013) 110(50):20320-20325
22. Lu L, Shao D, Qiu X, Sun L, Yan W, Zhou X, Yang L, He Y, Yu S, Xing Y. Natural variation and artificial selection in four genes determine grain shape in rice. New Phytol. (2013) 200:1269–1280
23. Yan W, Liu H, Zhou X, Li Q, Zhang J, Lu L, Liu T, Liu H, Zhang C, Zhang Z, Shen G, Yao W, Chen H, Yu S, Xie W, Xing Y*. Natural variation in Ghd7.1 plays an important role in grain yield and adaptation in rice. Cell Res (2013) 23(7):969–71
24. Zhang F, Jiang YZ, Yu S, Ali J, Paterson AH, Khush GS, Xu JL, Gao YM, Fu BY, Lafitte R, Li ZK*. Three genetic systems controlling growth, development and productivity of rice (Oryza sativa L.): a reevaluation of the ‘Green Revolution’. Theor Appl Genet (2013) 126:1011–1024
25. Wang P, Zhou GL, Cui KH, Li ZK, Yu S*. Clustered QTL for source leaf size and yield traits in rice (Oryza sativa L.) Mol Breeding (2012) 29: 99–113
26. Qiu XJ, Gong R, Tan YB, Yu S*. Mapping and characterization of the major quantitative trait locus qSS7 associated with increased length and decreased width of rice seeds. Theor Appl Genet (2012) 125: 1717–1726
27. Qu Z, Li L, Luo J, Wang P, Yu S, Mou T, Zheng X, Hu Z. QTL mapping of combining ability and heterosis of agronomic traits in rice backcross recombinant inbred Lines and hybrid crosses. PLoS ONE (2012) 7(1): e28463
328. Wang P, Xing YZ, Li ZK, Yu S*. Improving rice yield and quality by QTL pyramiding. Mol Breeding (2012) 29:903–913
29. Wang P, Zhou G, Yu H, Yu S. Fine mapping a major QTL for flag leaf size and yield-related traits in rice. Theor Appl Genet (2011) 123:1319–1330
30. Li M, Sun P, Zhou H, Chen S, Yu S*. Identification of quantitative trait loci associated with germination using chromosome segment substitution lines of rice (Oryza sativa L.). Theor Appl Genet (2011) 123:411–420
31. Ding ZH, Wang CR, Chen S, Yu S*. Diversity and selective sweep in the OsAMT1;1 genomic region of rice. BMC Evol Biology (2011) 11: 61. http://www.biomedcentral.com /1471-2148/11/61
32. Kovi MR, Zhang Y, Yu S, Yang G, Yan W, Xing Y*. Candidacy of a chitin-inducible gibberellin-responsive gene for a major locus affecting plant height in rice that is closely linked to Green Revolution gene sd1. Theor Appl Genet (2011) 123:705–714.
33. Wang CR, Chen S, Yu S*. Functional markers developed from multiple loci in GS3 for fine marker-assisted selection of grain length in rice. Theor Appl Genet (2011) 122: 905–913
34. Yan WH#, Wang P#, Chen HX, Zhou HJ, Li QP, Wang CR, Ding ZH, Zhang Y, Yu S*, Xing YZ*, Zhang Q. A Major QTL, Ghd8, plays pleiotropic roles in regulating grain productivity, plant height, and heading date in rice. Mol Plant (2011) 4: 319–330
35. Tan CJ, Sun YJ, Xu HS, Yu S*. Identification of quantitative trait locus and epistatic interaction for degenerated spikelets on the top of panicle in rice. Plant Breeding (2011) 130: 177–184
36. Ali ML, Sanchez PL, Yu S, Lorieux M, Eizenga GC*. Chromosome segment substitution lines: A powerful tool for the introgression of valuable genes from oryza wild species into cultivated rice (O. sativa). Rice (2010) 3: 218–234
3.7 Wang J, Yu HH, Xie WB, Xing YZ, Yu S, Xu CG, Li XH, Xiao JH, Zhang Q*. A global analysis of QTLs for expression variations in rice shoots at the early seedling stage. The Plant J (2010) 63: 1063–1074
38. Xie W, Feng Q, Yu H, Huang X, Zhao Q, Xing Y, Yu S, Han B, Zhang Q*. Parent-independent genotyping for constructing an ultrahigh-density linkage map based on population sequencing. Proc Natl Acad Sci USA (2010) 107: 10578–10583
39. Mao HL, Sun SY, Yao JL, Wang CR, Yu S, Xu CG, Li XH, Zhang Q*. Linking differential domain functions of the GS3 protein to natural variation of grain size in rice. Proc Natl Acad Sci. USA (2010) 107: 19579–19584
40. Wen WW, Mei HW, Feng FJ, Yu S, Huang ZC, Wu JH, Chen, Xu XY, Luo L*. Population structure and association mapping on chromosome 7 using a diverse panel of Chinese germplasm of rice (Oryza sativa L.). Theor Appl Genet (2009) 119:459–470
41. Fan CC, Yu S, Wang CR, Xing Y*. A causal C–A mutation in the second exon of GS3 highly associated with rice grain length and validated as a functional marker. Theor Appl Genet (2009) 118:465–472
42. Zhao LN#, Zhou HJ#, Lu LX, Liu L, Li XH, Lin YJ*, Yu S*. Identification of quantitative trait loci controlling rice mature seed culturability using chromosomal segment substitution lines. Plant Cell Rep (2009) 28:247–256
43. Wang Y, Sun YJ, Chen DY and Yu S*. Analysis of quantitative trait loci in response to nitrogen and phosphorus deficiency in rice using chromosomal segment substitution lines. Acta Agron Sin (2009) 35(4): 580–587
44. Zeng B, Li Min, Yang ZY, Tan CJ, Dong HL and Yu S*. Mapping of a novel semisterile pollen QTL in rice. Acta Agron Sin (2009) 35(9): 1584–1589
45. Zhu LH, Zhong DB, Xu JL, Yu S, Li Z*. Differential expression of lodging resistance related QTLs in rice (Oryza sativa L.). Plant Sci (2008) 175: 898–905
46. Xue W, Xing Y, Weng X, Zhao Yu, Tang W, Wang Lei, Zhou H, Yu S, Xu C, Li X, Zhang Q*. Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice. Nature Genet (2008) 40(6):761–767
47. Cui K, Huang J, Xing Y, Yu S, Xu C, Peng S*. Mapping QTLs for seedling characteristics under different water supply conditions in rice (Oryza sativa). Physiologia Plantarum (2008) 132: 53–68
48. Li ZK, Arif M, Zhong DB, Fu BY, Xu JL, Domingo-Rey J, Ali J, Vijayakumar CHM, Yu S, Khush GS*. Complex genetic networks underlying the defensive system of rice (Oryza sativa L.) to Xanthomonas oryzae pv. Oryzae. Proc Natl Acad Sci. USA (2006) 103: 7994–7999
49. Ali AJ, Xu JL, Ismail AM, Fu BY, Vijaykumar CHM, Gao YM, Domingo J, Maghirang R, Yu S, Gregorio G, Yanaghihara S, Cohen M, Carmen B, Mackill D, Li Z*. Hidden diversity for abiotic and biotic stress tolerances in the primary gene pool of rice revealed by a large backcross breeding program. Field Crops Res (2006) 97: 66–76
50. Lafitte HR, Li ZK, Vijayakumar CHM, Gao YM, Shi Y, Xu JL, Fu BY, Yu S, Ali AJ, Domingo J, Maghirang R, Torres R, Mackill D. Improvement of rice drought tolerance through backcross breeding: Evaluation of donors and selection in drought nurseries. Field Crops Res (2006) 97:77–86
51. Zhang ZH, Yu S, Yu T, Huang Z, Zhu Y*. Mapping quantitative trait loci (QTLs) for seedling-vigor using recombinant inbred lines of rice. Field Crop Res (2005) 90:161-170
52. Xu JL, Yu S, Luo LJ, Zhong DB, Mei HW, Li Z*. Molecular dissection of the primary sink size and its related traits in rice. Plant Breeding (2004) 123:43–50
53. Li ZK, Yu S, Lafitte HR, Huang N, Courtois B, Hittalmani S, Vijayakumar CHM, Liu GF, Wang GC, Shashidhar HE, Zhuang JY, Zheng KL, Singh VP, Sidhu JS, Srivantaneeyakul S, Khush GS. QTL x environment interactions in rice. I. Heading date and plant height. Theor Appl Genet (2003) 108: 141–153
54. Yu S#, Xu WJ#, Vijayakumar CH, Ali J, Fu BY, Xu JL, Jiang YZ, Marghirang R, Domingo J, Aquino C, Virmani SS, Li Z*. Molecular diversity and multilocus organization of the parental lines used in the International Rice Molecular Breeding Program. Theor Appl Genet (2003) 108:131–-140
55. Cui KH, Peng SB, Xing YZ, Yu S, Xu CG, Zhang Q*. Molecular dissection of the genetic relationships of source, sink and transport tissue with yield traits in rice. Theor Appl Genet (2003) 106:649–-658
56. Hua JP, Xing YZ, Wu W, Xu CG, Sun X, Yu S, Zhang Q*. Single-locus heterotic effects and dominance by dominance interactions can adequately explain the genetic basis of heterosis in an elite rice hybrid. Proc Natl Acad Sci USA (2003) 100: 2574–2579
57. Cui KH, Peng SB, Xing YZ, Xu CG, Yu S, Zhang Q*. Molecular dissection of seedling-vigor and associated physiological traits in rice. Theor Appl Genet (2002) 105:745–753
58. Hua JP, Xing YZ, Xu CG, Sun XL, Yu S, Zhang Q*. Genetic dissection of an elite rice hybrid revealed that heterozygotes are not always advantageous for performance. Genetics (2002) 162:1885–1895
59. Yu S, JX. Li, CG. Xu, YF. Tan, XH. Li, Zhang Q*. Identification of quantitative trait loci and epistatic interaction for plant height and heading date in rice. Theor Appl Genet (2002) 104: 619–625
60. Li JX, Yu S, Xu CG, Tan YF, Gao YJ, Li XH, Zhang Q*. Analyzing quantitative trait loci for yield using a vegetatively replicated F2 population from a cross between the parents of an elite rice hybrid. Theor Appl Genet (2000) 101: 248–254
61. Tan YF, Xing YZ, Li JX, Yu S, Xu CG, Zhang Q*. Genetic bases of appearance quality of rice grains in Shanyou 63, an elite rice hybrid. Theor Appl Genet (2000) 101:823–829
62. Tan YF, Li JX, Yu S, Xu CG, Zhang Q*. The three important traits for cooking and eating quality of rice grains are controlled by a single locus in an elite rice hybrid, Shanyou 63, Theor Appl Genet (1999) 99: 642–648
63. Yu S, Li JX, Xu CG, Tan YF, Gao YJ, Li XH, Zhang Q*. Epistasis plays an important role as the genetic basis of heterosis in rice. Science in China (series C) (1998) 41(3): 293–302
64. Yao FY, Xu CG, Yu S, Zhang Q*. Mapping and genetic analysis of two fertility restorer loci in the wild-abortive cytoplasmic male sterility system of rice (Oryza sativa L.) Euphytica (1997) 98:183–187
65. Yu S, Li JX, Xu CG, Tan YF, Gao YJ, Li XH, Zhang Q* and Saghai Maroof MA Importance of epistasis as the genetic basis of heterosis in an elite rice hybrid. Proc Natl Acad Sci. USA (1997) 94: 9226–9231
66.餘四斌*,熊銀,肖景華,羅利軍張啟發(2016).雜交稻與綠色超級稻.科學通報61:1-7
67.餘四斌*,孫文強,王記林,黎志康(2016).水稻種質資源及其在功能基因組中的應用.生命科學28:1121-1128
68.餘四斌*,湯欣欣,羅利軍(2016).功能基因組與綠色超級稻培育的研究進展.生命科學28:1287-1294
69.餘四斌(2010)水稻重要性狀的等位基因研究進展.分子植物育種8(6):1059–1067
70.陳雅,包亮,王利凱,趙磊,餘四斌,須健*(2012)水稻冠根數目多樣性生長素的關係.華中農業大學學報31:410-413
71.李雪梅,何宗順,餘四斌,陳國興吳昌銀*(2012)水稻穗形態建成基因PMM1的遺傳分析與初步定位.華中農業大學學報31:10-15
72.孫永建,周濟,徐華山,餘四斌*(2010)利用代換系分析水稻株高QTL及其互作效應.分子植物育種8:1068–1073
73.呂海霞,周廣生,丁澤紅,孫永建,餘四斌*(2010)水稻染色體片段代換系對氮反應的QTL分析.分子植物育種8:1074–1081
74.張晨昕,邱先進,董華林,餘四斌*(2010)野生稻染色體片段代換系構建及其效應分析.分子植物育種8:1113–1119
75.董華林,張晨昕,曾波,孫文強,餘四斌*(2009)利用野生稻高代回交群體分析水稻農藝性狀QTL.華中農業大學學報28:645-650
76.陳慶全,餘四斌,李春海,牟同敏*(2008)水稻抽穗開花期耐熱性QTL的定位分析.中國農業科學41:315-321
77.徐華山,孫永建,周紅菊,餘四斌*(2007)構建水稻優良恢復系背景的重疊片段代換系及其效應分析.作物學報33:979–986
78.陳慶全,穆俊祥,周紅菊,餘四斌*(2007)利用基礎導入系分析粳稻基因的遺傳效應.中國農業科學40:2387–2394
79.餘四斌*,穆俊祥,趙勝傑,周紅菊,譚友斌,徐才國,羅利軍,張啟發(2005)以珍汕97B和9311為背景的導入系構建及其篩選鑒定.分子植物育種3:629–636
80.周紅菊,穆俊祥,趙勝傑,餘四斌*(2005)水稻高世代回交導入系耐鹽性的遺傳研究.分子植物育種3:716–720
81.趙勝傑,王重榮,餘四斌*(2004)轉基因種子檢測的二維取樣分析方法.農業生物技術學報12:608-609

教材與著作

1.《作物種子學》(第二版)副主編,2019,中國農業出版社
2.《作物功能基因組學》,參編,2019,科學出版社
3.《種子加工與貯藏》(第二版),參編,2019,中國農業出版社
4.《遺傳學》(第三版),參編,2017,高等教育出版社
5.《資源節約型、環境友好型農業生產體系的理論與實踐》,參編,2015,科學出版社
6.《種子檢驗學》,參編,2015,科學出版社
7.《綠色超級稻的構想與實踐》,參編,2010,科學出版社
8.《中國水稻遺傳育種與品種系譜》,參編,2010,中國農業出版社
9.《植物生物技術》,副主編,2004,科學出版社
10.《RiceBreedingandGenetics:ResearchPrioritiesandChallenges》(J.SNanda,ed),Oxford&IBHPublishCo.(1999)PP.241–270

主要項目

基因克隆新技術研究,轉基因專項,2008-2010。
參與全球水稻分子育種計劃,948項目,2006-2010。
培育綠色超級稻,比爾與梅林達?蓋茨基金會項目,2008-2010。
水稻高產優質基因發掘與利用,863項目,2006-2009。

獲得榮譽

獲獎時間獲得獎項
1993年獲國家教委科技進步三等獎
1998年湖北省首屆優秀博士學位論文
1999年獲廣東省政府科技進步獎
2000年獲湖北省政府科技進步獎(三等)
2004年中國農學會青年科技獎
2006年入選教育部跨世紀優秀人才支持計劃
2007年上海市科學技術獎(一等獎)
2021年8月6日入選現代農業產業技術體系崗位科學家候選人名單

發明專利

1.餘四斌,孫文強,高大偉,王重榮。一種水稻基因OsAP2-6及製備方法和應用。專利號,ZL201310731026.9(授權公告日2018.4.10)
2.餘四斌,邱先進,王記林,孫文強。一種水稻粒型基因qSS7及製備方法和應用。專利號,ZL20131070753447.1(授權公告日2018.4.20)
3.餘四斌,熊銀,肖雄峰,袁志陽,張超普。水稻基因OsEIN2L及其應用。專利號ZL201610292521.8(授權公告日2019.9.10)
4.餘四斌,袁志陽,孫文強,熊銀,龔蓉,張佳寧。基於KASP技術用於水稻產量基因分型的引物組合及其應用。專利號ZL201710297282.X(授權公告日2019.7.19)
5.餘四斌,袁志陽,孫文強,凡凱,夏雨。基於KASP技術用於水稻特殊營養物質基因分型的引物及應用。ZL201710751904.1(授權公告日20200424)
6.餘四斌,孫文強,夏雨,張麗婷,袁志陽。用於鑒別稻米脂肪酸品質的DNA分子標記及其應用。ZL201710751127.0(授權公告日20200609)
7.王記林,餘四斌,袁志陽,邱先進。一組用於改良稻米品質的分子標記及水稻改良方法和應用。ZL201710355389.5(授權公告日20200508)
8.餘四斌,袁志陽,蔡星星,凡凱,田莉,邱先進。一種水稻溫敏核不育基因tms3突變體及其分子標記與應用。ZL201910501858.9(授權公告日20200901)
9.餘四斌,高大偉,孫文強,王電文。一種水稻基因OsPGSIP1及其應用。ZL2018.10945403.1(授權公告日20200901)
10.餘四斌,袁志陽,凡凱,田莉,熊銀。一種水稻種子耐貯藏基因OsGH3-2及其分子標記的應用。ZL201910554967.7(授權公告日20201002)